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Complement activation, regulation, and molecular basis for complement-related diseases

The EMBO journal, 2015-11, Vol.34 (22), p.2735-2757

2015

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Analysis of Factor D Isoforms in Malpuech-Michels-Mingarelli-Carnevale Patients Highlights the Role of MASP-3 as a Maturase in the Alternative Pathway of Complement

The Journal of immunology (1950), 2017-09, Vol.199 (6), p.2158-2170

2017

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Structure and activation of C1, the complex initiating the classical pathway of the complement cascade

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (5), p.986-991

2017

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COLLECTINS AND FICOLINS: Humoral Lectins of the Innate Immune Defense

Annual review of immunology, 2003-01, Vol.21 (1), p.547-578

2003

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Alpha-synuclein activates the classical complement pathway and mediates complement-dependent cell toxicity

Journal of neuroinflammation, 2021-08, Vol.18 (1), p.177-177, Article 177

2021

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Structural basis for activation of the complement system by component C4 cleavage

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (38), p.15425-15430

2012

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Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System

Frontiers in immunology, 2019-08, Vol.10, p.2007-2007

2019

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Biological variations of MASP-3 and MAp44, two splice products of the MASP1 gene involved in regulation of the complement system

Journal of immunological methods, 2010-09, Vol.361 (1-2), p.37-50

2010

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Extensive Basal Level Activation of Complement Mannose-Binding Lectin-Associated Serine Protease-3: Kinetic Modeling of Lectin Pathway Activation Provides Possible Mechanism

Frontiers in immunology, 2017-12, Vol.8, p.1821-1821

2017

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Serum concentrations of lectin-pathway components in healthy neonates, children and adults: mannan-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2)

Pediatric allergy and immunology, 2011-06, Vol.22 (4), p.424-430

2011

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Cooperation between MASP-1 and MASP-2 in the generation of C3 convertase through the MBL pathway

International immunology, 2007-02, Vol.19 (2), p.141-149

2007

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Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin–Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H–Related Protein-5 (FHR5) Deposition

Kidney international reports, 2018-03, Vol.3 (2), p.426-438

2018

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Plasma Lectin Pathway Complement Proteins in Patients With COVID-19 and Renal Disease

Frontiers in immunology, 2021-04, Vol.12, p.671052-671052

2021

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Mitochondria and the Lectin Pathway of Complement

The Journal of biological chemistry, 2013-03, Vol.288 (12), p.8016-8027

2013

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MAPK phosphatase-1 is required for regulatory natural autoantibody-mediated inhibition of TLR responses

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (48), p.19745-19750

2012

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Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D

Frontiers in immunology, 2020-02, Vol.11, p.201-201

2020

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Local inflammation induces complement crosstalk which amplifies the antimicrobial response

PLoS pathogens, 2009-01, Vol.5 (1), p.e1000282-e1000282

2009

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A Single-Domain Antibody Targeting Complement Component C5 Acts as a Selective Inhibitor of the Terminal Pathway of the Complement System and Thus Functionally Mimicks the C-Terminal Domain of the Staphylococcus aureus SSL7 Protein

Frontiers in immunology, 2018-11, Vol.9, p.2822-2822

2018

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Non-synonymous polymorphisms in the FCN1 gene determine ligand-binding ability and serum levels of M-ficolin

PloS one, 2012-11, Vol.7 (11), p.e50585-e50585

2012

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Investigations on the pattern recognition molecule M-ficolin: quantitative aspects of bacterial binding and leukocyte association

Journal of leukocyte biology, 2011-09, Vol.90 (3), p.425-437

2011

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Phase I safety, tolerability, and pharmacokinetic study of recombinant human mannan-binding lectin

Journal of Clinical Immunology, 2006-09, Vol.26 (5), p.465-475

2006

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Serum Mannan-Binding Lectin-Associated Serine Protease 2 Levels in Colorectal Cancer: Relation to Recurrence and Mortality

Clinical cancer research, 2005-02, Vol.11 (4), p.1441-1446

2005

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Mannan-binding lectin deficiency modulates the humoral immune response dependent on the genetic environment

Immunology, 2009-06, Vol.127 (2), p.279-288

2009

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Complement activation, regulation, and molecular basis for complement-related diseases

Analysis of Factor D Isoforms in Malpuech-Michels-Mingarelli-Carnevale Patients Highlights the Role of MASP-3 as a Maturase in the Alternative Pathway of Complement

Structure and activation of C1, the complex initiating the classical pathway of the complement cascade

COLLECTINS AND FICOLINS: Humoral Lectins of the Innate Immune Defense

Alpha-synuclein activates the classical complement pathway and mediates complement-dependent cell toxicity

Structural basis for activation of the complement system by component C4 cleavage

Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System

Biological variations of MASP-3 and MAp44, two splice products of the MASP1 gene involved in regulation of the complement system

Extensive Basal Level Activation of Complement Mannose-Binding Lectin-Associated Serine Protease-3: Kinetic Modeling of Lectin Pathway Activation Provides Possible Mechanism

Serum concentrations of lectin-pathway components in healthy neonates, children and adults: mannan-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2)

Cooperation between MASP-1 and MASP-2 in the generation of C3 convertase through the MBL pathway

Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin–Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H–Related Protein-5 (FHR5) Deposition

Plasma Lectin Pathway Complement Proteins in Patients With COVID-19 and Renal Disease

Mitochondria and the Lectin Pathway of Complement

Associations of Ficolins With Hematological Malignancies in Patients Receiving High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantations

MAPK phosphatase-1 is required for regulatory natural autoantibody-mediated inhibition of TLR responses

Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D

Local inflammation induces complement crosstalk which amplifies the antimicrobial response

A Single-Domain Antibody Targeting Complement Component C5 Acts as a Selective Inhibitor of the Terminal Pathway of the Complement System and Thus Functionally Mimicks the C-Terminal Domain of the Staphylococcus aureus SSL7 Protein

Non-synonymous polymorphisms in the FCN1 gene determine ligand-binding ability and serum levels of M-ficolin

The Role of Complement Activating Collectins and Associated Serine Proteases in Patients With Hematological Malignancies, Receiving High-Dose Chemotherapy, and Autologous Hematopoietic Stem Cell Transplantations (Auto-HSCT)

Investigations on the pattern recognition molecule M-ficolin: quantitative aspects of bacterial binding and leukocyte association

Phase I safety, tolerability, and pharmacokinetic study of recombinant human mannan-binding lectin

Serum Mannan-Binding Lectin-Associated Serine Protease 2 Levels in Colorectal Cancer: Relation to Recurrence and Mortality

Mannan-binding lectin deficiency modulates the humoral immune response dependent on the genetic environment

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