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Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions

Angewandte Chemie (International ed.), 2011-01, Vol.50 (1), p.314-318

International ed. in English, 2011

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Novel β‐Glucocerebrosidase Activators That Bind to a New Pocket at a Dimer Interface and Induce Dimerization

Angewandte Chemie International Edition, 2021-03, Vol.60 (10), p.5436-5442

International ed. in English, 2021

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BACE1 inhibitors: A head group scan on a series of amides

Bioorganic & medicinal chemistry letters, 2013-07, Vol.23 (14), p.4239-4243

2013

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Aleglitazar, a new, potent, and balanced dual PPARα/γ agonist for the treatment of type II diabetes

Bioorganic & medicinal chemistry letters, 2009-05, Vol.19 (9), p.2468-2473

2009

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Fragment-Based Screening Using Surface Plasmon Resonance Technology

Journal of biomolecular screening, 2009-04, Vol.14 (4), p.337-349

2009

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Tyramine fragment binding to BACE-1

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (4), p.1304-1307

2008

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Cation-π Interactions at the Active Site of Factor Xa: Dramatic Enhancement upon Stepwise N-Alkylation of Ammonium Ions

Angewandte Chemie (International ed.), 2009-01, Vol.48 (4), p.811-814

2009

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Novel β‐Glucocerebrosidase Activators That Bind to a New Pocket at a Dimer Interface and Induce Dimerization

Angewandte Chemie, 2021-03, Vol.133 (10), p.5496-5502

2021

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Structure-based design of indole propionic acids as novel PPARα/γ co-agonists

Bioorganic & medicinal chemistry letters, 2006-08, Vol.16 (15), p.4016-4020

2006

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Discovery of a factor Xa inhibitor (3 R,4 R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide} as a clinical candidate

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (17), p.5313-5319

2010

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Allosteric FBPase inhibitors gain 10(5) times in potency when simultaneously binding two neighboring AMP sites

Bioorganic & medicinal chemistry letters, 2008-08, Vol.18 (16), p.4708-4712

2008

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Sulfonylureido thiazoles as fructose-1,6-bisphosphatase inhibitors for the treatment of Type-2 diabetes

Bioorganic & medicinal chemistry letters, 2010-01, Vol.20 (2), p.594-599

2010

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Orally active aminopyridines as inhibitors of tetrameric fructose-1,6-bisphosphatase

Bioorganic & medicinal chemistry letters, 2011-06, Vol.21 (11), p.3237-3242

2011

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Synthesis and evaluation of anilinohexafluoroisopropanols as activators/modulators of LXRα and β

Bioorganic & medicinal chemistry letters, 2006-10, Vol.16 (19), p.5231-5237

2006

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Systematische Untersuchung von Halogenbrücken in Protein-Ligand- Wechselwirkungen

Angewandte Chemie, 2011-01, Vol.123 (1), p.329-334

2011

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A comparison of DNA and RNA quadruplex structures and stabilities

Bioorganic & medicinal chemistry, 2009-10, Vol.17 (19), p.6811-6815

2009

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Synthesis and Characterization of Binary, Highly Endothermic, and Extremely Sensitive 2,2′-Azobis(5-azidotetrazole)

Journal of the American Chemical Society, 2022-04, Vol.144 (14), p.6143-6147

2022

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Krapcho Decarboxylation of Ethyl-Carbazate: Synthetic Approach toward 1,1′-Diamino-5,5′-bistetrazole and Its Utilization as a High-Performing Metal-Free Initiator

Organic letters, 2022-03, Vol.24 (8), p.1747-1751

2022

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Tuning the Properties of 5‐Azido and 5‐Nitramino‐tetrazoles by Diverse Functionalization – General Concepts for Future Energetic Materials

Chemistry : a European journal, 2022-06, Vol.28 (36), p.e202200772-n/a

2022

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Polyazido-methyl Derivatives of Prominent Oxadiazole and Isoxazole Scaffolds: Synthesis, Explosive Properties, and Evaluation

Journal of organic chemistry, 2021-05, Vol.86 (9), p.6371-6380

2021

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Chemistry of 2,5-diaminotetrazole

Dalton transactions : an international journal of inorganic chemistry, 2022-08, Vol.51 (31), p.1186-11813

2022

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Combining Performance with Thermal Stability: Synthesis and Characterization of 5‐(3,5‐Dinitro‐1H‐pyrazol‐4‐yl)‐1H‐tetrazole and its Energetic Derivatives

Zeitschrift für anorganische und allgemeine Chemie (1950), 2020-08, Vol.646 (16), p.1380-1388

2020

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Hybridization of Dinitramide and Dicyanamide: Evaluation of Nitrocyanamide in Energetic Salts and Coordination Compounds

Crystal growth & design, 2022-01, Vol.22 (1), p.200-212

2022

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1‐Nitrimino‐5‐azidotetrazole: Extending Energetic Tetrazole Chemistry

ChemPlusChem (Weinheim, Germany), 2022-09, Vol.87 (9), p.e202200186-n/a

2022

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A rocky road toward a suitable TNT replacement – A closer look at three promising azoles

Propellants, explosives, pyrotechnics, 2023-08, Vol.48 (8)

2023

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Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions

Novel β‐Glucocerebrosidase Activators That Bind to a New Pocket at a Dimer Interface and Induce Dimerization

BACE1 inhibitors: A head group scan on a series of amides

Aleglitazar, a new, potent, and balanced dual PPARα/γ agonist for the treatment of type II diabetes

Fragment-Based Screening Using Surface Plasmon Resonance Technology

Tyramine fragment binding to BACE-1

Cation-π Interactions at the Active Site of Factor Xa: Dramatic Enhancement upon Stepwise N-Alkylation of Ammonium Ions

Novel β‐Glucocerebrosidase Activators That Bind to a New Pocket at a Dimer Interface and Induce Dimerization

Structure-based design of indole propionic acids as novel PPARα/γ co-agonists

Discovery of a factor Xa inhibitor (3 R,4 R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide} as a clinical candidate

Allosteric FBPase inhibitors gain 10(5) times in potency when simultaneously binding two neighboring AMP sites

Sulfonylureido thiazoles as fructose-1,6-bisphosphatase inhibitors for the treatment of Type-2 diabetes

Orally active aminopyridines as inhibitors of tetrameric fructose-1,6-bisphosphatase

Synthesis and evaluation of anilinohexafluoroisopropanols as activators/modulators of LXRα and β

Systematische Untersuchung von Halogenbrücken in Protein-Ligand- Wechselwirkungen

A comparison of DNA and RNA quadruplex structures and stabilities

Synthesis and Characterization of Binary, Highly Endothermic, and Extremely Sensitive 2,2′-Azobis(5-azidotetrazole)

Krapcho Decarboxylation of Ethyl-Carbazate: Synthetic Approach toward 1,1′-Diamino-5,5′-bistetrazole and Its Utilization as a High-Performing Metal-Free Initiator

Tuning the Properties of 5‐Azido and 5‐Nitramino‐tetrazoles by Diverse Functionalization – General Concepts for Future Energetic Materials

Polyazido-methyl Derivatives of Prominent Oxadiazole and Isoxazole Scaffolds: Synthesis, Explosive Properties, and Evaluation

Chemistry of 2,5-diaminotetrazole

Combining Performance with Thermal Stability: Synthesis and Characterization of 5‐(3,5‐Dinitro‐1H‐pyrazol‐4‐yl)‐1H‐tetrazole and its Energetic Derivatives

Hybridization of Dinitramide and Dicyanamide: Evaluation of Nitrocyanamide in Energetic Salts and Coordination Compounds

1‐Nitrimino‐5‐azidotetrazole: Extending Energetic Tetrazole Chemistry

A rocky road toward a suitable TNT replacement – A closer look at three promising azoles

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