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Helical Antimicrobial Peptide Foldamers Containing Non‐proteinogenic Amino Acids

ChemMedChem, 2021-04, Vol.16 (8), p.1226-1233

2021

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The Application of Microsampling Disks in Circular Dichroism Spectroscopy for Peptide and Nucleic Acid Drugs

Chemical and Pharmaceutical Bulletin, 2024/07/11, Vol.72(7), pp.658-663

2024

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N-Nitrosodimethylamine (NDMA) Formation from Ranitidine Impurities: Possible Root Causes of the Presence of NDMA in Ranitidine Hydrochloride

Chemical and Pharmaceutical Bulletin, 2021/09/01, Vol.69(9), pp.872-876

2021

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Design and synthesis of peptide-based chimeric molecules to induce degradation of the estrogen and androgen receptors

Bioorganic & medicinal chemistry, 2020-08, Vol.28 (15), p.115595-115595, Article 115595

2020

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Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (20), p.4865-4869

2016

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Development of Photoswitchable Estrogen Receptor Ligands

Chemical and Pharmaceutical Bulletin, 2020/04/01, Vol.68(4), pp.398-402

2020

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Facile Synthesis of Kwakhurin, a Marker Compound of Pueraria mirifica and Its Quantitative NMR Analysis for Standardization as a Reagent

Chemical and Pharmaceutical Bulletin, 2020/08/01, Vol.68(8), pp.797-801

2020

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Rapid Structure Determination of Ranitidine Hydrochloride API in Two Crystal Forms Using Microcrystal Electron Diffraction

Chemical and Pharmaceutical Bulletin, 2024/05/15, Vol.72(5), pp.471-474

2024

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Selective Degradation of Target Proteins by Chimeric Small-Molecular Drugs, PROTACs and SNIPERs

Pharmaceuticals (Basel, Switzerland), 2020-04, Vol.13 (4), p.74

2020

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Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design

Journal of medicinal chemistry, 2021-11, Vol.64 (21), p.15868-15882

2021

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Miroestrol Quantification in Pueraria mirifica Crude Drugs and Products by Single-Reference UPLC/PDA/MS Using Relative Molar Sensitivities to Kwakhurin

Chemical and Pharmaceutical Bulletin, 2021/06/01, Vol.69(6), pp.573-580

2021

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A Helix-Stabilized Cell-Penetrating Peptide as an Intracellular Delivery Tool

Chembiochem : a European journal of chemical biology, 2016-01, Vol.17 (2), p.137-140

2016

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Efficient synthesis of a multi-substituted diphenylmethane skeleton as a steroid mimetic

Bioorganic & medicinal chemistry letters, 2017-06, Vol.27 (11), p.2590-2593

2017

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Temperature-Dependent Formation of N-Nitrosodimethylamine during the Storage of Ranitidine Reagent Powders and Tablets

Chemical and Pharmaceutical Bulletin, 2020/10/01, Vol.68(10), pp.1008-1012

2020

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Development of a Hematopoietic Prostaglandin D Synthase-Degradation Inducer

ACS medicinal chemistry letters, 2021-02, Vol.12 (2), p.236-241

2021

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Approach to Establishment of Control Strategy for Oral Solid Dosage Forms Using Continuous Manufacturing

Chemical and Pharmaceutical Bulletin, 2021/02/01, Vol.69(2), pp.211-217

2021

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Plasmid DNA delivery by arginine-rich cell-penetrating peptides containing unnatural amino acids

Bioorganic & medicinal chemistry, 2016-06, Vol.24 (12), p.2681-2687

2016

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Development of Selective TGR5 Ligands Based on the 5,6,7,8‐Tetrahydro‐5,5,8,8‐tetramethylnaphthalene Skeleton

ChemMedChem, 2021-02, Vol.16 (3), p.458-462

2021

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Development of Amphipathic Antimicrobial Peptide Foldamers Based on Magainin 2 Sequence

ChemMedChem, 2019-11, Vol.14 (22), p.1911-1916

2019

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Design and synthesis of estrogen receptor degradation inducer based on a protein knockdown strategy

Bioorganic & medicinal chemistry letters, 2012-02, Vol.22 (4), p.1793-1796

2012

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Structure-activity relationship study of PROTACs against hematopoietic prostaglandin D2 synthase

RSC medicinal chemistry, 2022-12, Vol.13 (12), p.1495-1503

2022

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Development of an ON/OFF switchable fluorescent probe targeting His tag fused proteins in living cells

Bioorganic & medicinal chemistry letters, 2017-08, Vol.27 (15), p.3417-3422

2017

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Structural development of stapled short helical peptides as vitamin D receptor (VDR)–coactivator interaction inhibitors

Bioorganic & medicinal chemistry, 2015-03, Vol.23 (5), p.1055-1061

2015

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Rational design of novel amphipathic antimicrobial peptides focused on the distribution of cationic amino acid residues

MedChemComm, 2019-06, Vol.1 (6), p.896-9

2019

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Design and synthesis of cell-permeable fluorescent nitrilotriacetic acid derivatives

Bioorganic & medicinal chemistry, 2018-11, Vol.26 (20), p.5494-5498

2018

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Helical Antimicrobial Peptide Foldamers Containing Non‐proteinogenic Amino Acids

The Application of Microsampling Disks in Circular Dichroism Spectroscopy for Peptide and Nucleic Acid Drugs

N-Nitrosodimethylamine (NDMA) Formation from Ranitidine Impurities: Possible Root Causes of the Presence of NDMA in Ranitidine Hydrochloride

Design and synthesis of peptide-based chimeric molecules to induce degradation of the estrogen and androgen receptors

Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand

Development of Photoswitchable Estrogen Receptor Ligands

Facile Synthesis of Kwakhurin, a Marker Compound of Pueraria mirifica and Its Quantitative NMR Analysis for Standardization as a Reagent

Rapid Structure Determination of Ranitidine Hydrochloride API in Two Crystal Forms Using Microcrystal Electron Diffraction

Selective Degradation of Target Proteins by Chimeric Small-Molecular Drugs, PROTACs and SNIPERs

Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design

Miroestrol Quantification in Pueraria mirifica Crude Drugs and Products by Single-Reference UPLC/PDA/MS Using Relative Molar Sensitivities to Kwakhurin

A Helix-Stabilized Cell-Penetrating Peptide as an Intracellular Delivery Tool

Efficient synthesis of a multi-substituted diphenylmethane skeleton as a steroid mimetic

Temperature-Dependent Formation of N-Nitrosodimethylamine during the Storage of Ranitidine Reagent Powders and Tablets

Development of a Hematopoietic Prostaglandin D Synthase-Degradation Inducer

Approach to Establishment of Control Strategy for Oral Solid Dosage Forms Using Continuous Manufacturing

Plasmid DNA delivery by arginine-rich cell-penetrating peptides containing unnatural amino acids

Development of Selective TGR5 Ligands Based on the 5,6,7,8‐Tetrahydro‐5,5,8,8‐tetramethylnaphthalene Skeleton

Development of Amphipathic Antimicrobial Peptide Foldamers Based on Magainin 2 Sequence

Design and synthesis of estrogen receptor degradation inducer based on a protein knockdown strategy

Structure-activity relationship study of PROTACs against hematopoietic prostaglandin D2 synthase

Development of an ON/OFF switchable fluorescent probe targeting His tag fused proteins in living cells

Structural development of stapled short helical peptides as vitamin D receptor (VDR)–coactivator interaction inhibitors

Rational design of novel amphipathic antimicrobial peptides focused on the distribution of cationic amino acid residues

Design and synthesis of cell-permeable fluorescent nitrilotriacetic acid derivatives

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