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SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense

EMBO reports, 2016-06, Vol.17 (6), p.811-822

2016

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Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb

Immunity (Cambridge, Mass.), 2019-12, Vol.51 (6), p.1012-1027.e7

2019

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Regulation of TORC1 by Rag GTPases in nutrient response

Nature cell biology, 2008-08, Vol.10 (8), p.935-945

2008

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YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29

Nature cell biology, 2012-12, Vol.14 (12), p.1322-1329

2012

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Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

Cell, 2012-08, Vol.150 (4), p.780-791

2012

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Cell type-dependent function of LATS1/2 in cancer cell growth

Oncogene, 2019-04, Vol.38 (14), p.2595-2610

2019

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Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction

Molecular cell, 2018-10, Vol.72 (2), p.328-340.e8

2018

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Regulation of Cellular Metabolism by Protein Lysine Acetylation

Science (American Association for the Advancement of Science), 2010-02, Vol.327 (5968), p.1000-1004

2010

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The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation

Genes & development, 2010-06, Vol.24 (11), p.1106-1118

2010

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Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation

Genes & development, 2013-06, Vol.27 (11), p.1223-1232

2013

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TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition

The Journal of biological chemistry, 2009-05, Vol.284 (20), p.13355-13362

2009

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GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor

eLife, 2019-05, Vol.8

2019

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ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (9), p.4153-4158

2010

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Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

Genes & development, 2003-08, Vol.17 (15), p.1829-1834

2003

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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Nature cell biology, 2002-09, Vol.4 (9), p.648-657

2002

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Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation

Genes & development, 2016-05, Vol.30 (9), p.1086-1100

2016

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Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease

EMBO molecular medicine, 2013-06, Vol.5 (6), p.870-890

2013

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TSC1/TSC2 and Rheb have different effects on TORC1 and TORC2 activity

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (18), p.6811-6816

2006

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DSCAM functions as a netrin receptor in commissural axon pathfinding

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (8), p.2951-2956

2009

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Bnip3 Mediates the Hypoxia-induced Inhibition on Mammalian Target of Rapamycin by Interacting with Rheb

The Journal of biological chemistry, 2007-12, Vol.282 (49), p.35803-35813

2007

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Regulation of mTORC1 by the Rab and Arf GTPases

The Journal of biological chemistry, 2010-06, Vol.285 (26), p.19705-19709

2010

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Biochemical and Functional Characterizations of Small GTPase Rheb and TSC2 GAP Activity

Molecular and Cellular Biology, 2004-09, Vol.24 (18), p.7965-7975

2004

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A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression

American Journal of Physiology: Cell Physiology, 2008-09, Vol.295 (3), p.C836-C843

2008

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A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

Genes & development, 2010-01, Vol.24 (1), p.72-85

2010

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The Stress-inducted Proteins RTP801 and RTP801L Are Negative Regulators of the Mammalian Target of Rapamycin Pathway

The Journal of biological chemistry, 2005-03, Vol.280 (11), p.9769-9772

2005

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SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense

Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb

Regulation of TORC1 by Rag GTPases in nutrient response

YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29

Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

Cell type-dependent function of LATS1/2 in cancer cell growth

Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction

Regulation of Cellular Metabolism by Protein Lysine Acetylation

The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation

Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation

TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition

GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation

Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease

TSC1/TSC2 and Rheb have different effects on TORC1 and TORC2 activity

DSCAM functions as a netrin receptor in commissural axon pathfinding

Bnip3 Mediates the Hypoxia-induced Inhibition on Mammalian Target of Rapamycin by Interacting with Rheb

Regulation of mTORC1 by the Rab and Arf GTPases

Biochemical and Functional Characterizations of Small GTPase Rheb and TSC2 GAP Activity

A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

The Stress-inducted Proteins RTP801 and RTP801L Are Negative Regulators of the Mammalian Target of Rapamycin Pathway

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