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Reductive carboxylation supports growth in tumour cells with defective mitochondria

Nature (London), 2012-01, Vol.481 (7381), p.385-388

2012

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The Glycolytic Shift in Fumarate-Hydratase-Deficient Kidney Cancer Lowers AMPK Levels, Increases Anabolic Propensities and Lowers Cellular Iron Levels

Cancer cell, 2011-09, Vol.20 (3), p.315-327

2011

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Targeting ABL1-Mediated Oxidative Stress Adaptation in Fumarate Hydratase-Deficient Cancer

Cancer cell, 2014-12, Vol.26 (6), p.840-850

2014

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Metabolic reprogramming for producing energy and reducing power in fumarate hydratase null cells from hereditary leiomyomatosis renal cell carcinoma

PloS one, 2013-08, Vol.8 (8), p.e72179

2013

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Preclinical efficacy of dual mTORC1/2 inhibitor AZD8055 in renal cell carcinoma harboring a TFE3 gene fusion

BMC cancer, 2019-09, Vol.19 (1), p.917-917, Article 917

2019

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Tumor necrosis factor-alpha regulates the Hypocretin system via mRNA degradation and ubiquitination

Biochimica et biophysica acta, 2011-04, Vol.1812 (4), p.565-571

2011

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Increasing reactive oxygen species as a therapeutic approach to treat hereditary leiomyomatosis and renal cell carcinoma

Cell cycle (Georgetown, Tex.), 2010-10, Vol.9 (20), p.4183-4189

2010

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SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery

JNCI : Journal of the National Cancer Institute, 2016-01, Vol.108 (1), p.djv287

2016

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VPO1 mediates oxidation of LDL and formation of foam cells

Oncotarget, 2016-06, Vol.7 (24), p.35500-35511

2016

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Heterogeneous adaptation of cysteine reactivity to a covalent oncometabolite

The Journal of biological chemistry, 2020-09, Vol.295 (39), p.13410-13418

2020

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Characterization of genetically defined sporadic and hereditary type 1 papillary renal cell carcinoma cell lines

Genes chromosomes & cancer, 2021-06, Vol.60 (6), p.434-446

2021

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Proteasome inhibition disrupts the metabolism of fumarate hydratase- deficient tumors by downregulating p62 and c-Myc

Scientific reports, 2019-12, Vol.9 (1), p.18409-11, Article 18409

2019

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S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase

Scientific reports, 2015-02, Vol.5 (1), p.8453-8453, Article 8453

2015

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Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276)

Genes chromosomes & cancer, 2017-10, Vol.56 (10), p.719-729

2017

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A novel fumarate hydratase-deficient HLRCC kidney cancer cell line, UOK268: a model of the Warburg effect in cancer

Cancer genetics, 2012-07, Vol.205 (7), p.377-390

2012

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Targeting HIF2α translation with Tempol in VHL-deficient clear cell renal cell carcinoma

Oncotarget, 2012-11, Vol.3 (11), p.1472-1482

2012

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Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species

Molecular and cellular biology, 2009-08, Vol.29 (15), p.4080-4090

2009

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The UOK 257 cell line: a novel model for studies of the human Birt–Hogg–Dubé gene pathway

Cancer genetics and cytogenetics, 2008-01, Vol.180 (2), p.100-109

2008

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Medicarpin suppresses lung cancer cell growth in vitro and in vivo by inducing cell apoptosis

Acta pharmaceutica (Zagreb, Croatia), 2024-03, Vol.74 (1), p.149-164

2024

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Ligustilide induces apoptosis and reduces proliferation in human bladder cancer cells by NFκB1 and mitochondria pathway

Chemical biology & drug design, 2023-06, Vol.101 (6), p.1252-1261

2023

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Peimenine unleashes therapeutic promise in urothelial bladder cancer: inhibition of proliferation, induction of cell death and modulation of key pathways

Chemical biology & drug design, 2024-06, Vol.103 (6), p.e14528-n/a

2024

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Glabridin inhibits urothelial bladder carcinoma cell growth in vitro and in vivo by inducing cell apoptosis and cell cycle arrest

Chemical biology & drug design, 2023-03, Vol.101 (3), p.581-592

2023

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Simple and efficient synthesis of novel glycosyl thiourea derivatives as potential antitumor agents

European journal of medicinal chemistry, 2008-12, Vol.43 (12), p.2778-2783

2008

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Reductive carboxylation supports growth in tumour cells with defective mitochondria

The Glycolytic Shift in Fumarate-Hydratase-Deficient Kidney Cancer Lowers AMPK Levels, Increases Anabolic Propensities and Lowers Cellular Iron Levels

Targeting ABL1-Mediated Oxidative Stress Adaptation in Fumarate Hydratase-Deficient Cancer

Metabolic reprogramming for producing energy and reducing power in fumarate hydratase null cells from hereditary leiomyomatosis renal cell carcinoma

Preclinical efficacy of dual mTORC1/2 inhibitor AZD8055 in renal cell carcinoma harboring a TFE3 gene fusion

Tumor necrosis factor-alpha regulates the Hypocretin system via mRNA degradation and ubiquitination

Increasing reactive oxygen species as a therapeutic approach to treat hereditary leiomyomatosis and renal cell carcinoma

SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery

VPO1 mediates oxidation of LDL and formation of foam cells

Heterogeneous adaptation of cysteine reactivity to a covalent oncometabolite

Characterization of genetically defined sporadic and hereditary type 1 papillary renal cell carcinoma cell lines

Proteasome inhibition disrupts the metabolism of fumarate hydratase- deficient tumors by downregulating p62 and c-Myc

S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase

Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276)

A novel fumarate hydratase-deficient HLRCC kidney cancer cell line, UOK268: a model of the Warburg effect in cancer

Targeting HIF2α translation with Tempol in VHL-deficient clear cell renal cell carcinoma

Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species

The UOK 257 cell line: a novel model for studies of the human Birt–Hogg–Dubé gene pathway

Medicarpin suppresses lung cancer cell growth in vitro and in vivo by inducing cell apoptosis

Ligustilide induces apoptosis and reduces proliferation in human bladder cancer cells by NFκB1 and mitochondria pathway

Peimenine unleashes therapeutic promise in urothelial bladder cancer: inhibition of proliferation, induction of cell death and modulation of key pathways

Glabridin inhibits urothelial bladder carcinoma cell growth in vitro and in vivo by inducing cell apoptosis and cell cycle arrest

Simple and efficient synthesis of novel glycosyl thiourea derivatives as potential antitumor agents

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