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TRAF6 inhibits colorectal cancer metastasis through regulating selective autophagic CTNNB1/β-catenin degradation and is targeted for GSK3B/GSK3β-mediated phosphorylation and degradation

Autophagy, 2019-09, Vol.15 (9), p.1506-1522

2019

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Notoginsenoside R1 alleviates oxidized low-density lipoprotein-induced apoptosis, inflammatory response, and oxidative stress in HUVECS through modulation of XIST/miR-221-3p/TRAF6 axis

Cellular signalling, 2020-12, Vol.76, p.109781-109781, Article 109781

2020

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Inhibition of TRAF6 ubiquitin-ligase activity by PRDX1 leads to inhibition of NFKB activation and autophagy activation

Autophagy, 2018-08, Vol.14 (8), p.1347-1358

2018

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Downregulation of lncRNA NEAT1 Ameliorates LPS-Induced Inflammatory Responses by Promoting Macrophage M2 Polarization via miR-125a-5p/TRAF6/TAK1 Axis

Inflammation, 2020-08, Vol.43 (4), p.1548-1560

2020

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TRAF6 directs FOXP3 localization and facilitates regulatory T‐cell function through K63‐linked ubiquitination

The EMBO journal, 2019-05, Vol.38 (9), p.n/a

2019

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Long non‐coding RNA MEG3 inhibits M2 macrophage polarization by activating TRAF6 via microRNA‐223 down‐regulation in viral myocarditis

Journal of cellular and molecular medicine, 2020-11, Vol.24 (21), p.12341-12354

2020

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Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

Molecular cell, 2018-09, Vol.71 (5), p.745-760.e5

2018

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Cocaine-Mediated Downregulation of miR-124 Activates Microglia by Targeting KLF4 and TLR4 Signaling

Molecular neurobiology, 2018-04, Vol.55 (4), p.3196-3210

2018

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Toxoplasma GRA15 limits parasite growth in IFNγ‐activated fibroblasts through TRAF ubiquitin ligases

The EMBO journal, 2020-05, Vol.39 (10), p.e103758-n/a

2020

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LncRNA NEAT1 accelerates renal mesangial cell injury via modulating the miR-146b/TRAF6/NF-κB axis in lupus nephritis

Cell and tissue research, 2020-12, Vol.382 (3), p.627-638

2020

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The lncRNA ROR/miR-124-3p/TRAF6 axis regulated the ischaemia reperfusion injury-induced inflammatory response in human cardiac myocytes

Journal of bioenergetics and biomembranes, 2019-12, Vol.51 (6), p.381-392

2019

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Long non-coding RNA HCG18 promotes M1 macrophage polarization through regulating the miR-146a/TRAF6 axis, facilitating the progression of diabetic peripheral neuropathy

Molecular and cellular biochemistry, 2021-01, Vol.476 (1), p.471-482

2021

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Neobavaisoflavone inhibits osteoclastogenesis through blocking RANKL signalling‐mediated TRAF6 and c‐Src recruitment and NF‐κB, MAPK and Akt pathways

Journal of cellular and molecular medicine, 2020-08, Vol.24 (16), p.9067-9084

2020

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SASH1 knockdown suppresses TRAF6 ubiquitination to regulate hemangioma progression by mediating EZH2 degradation

Experimental cell research, 2022-09, Vol.418 (1), p.113270-113270, Article 113270

2022

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Hedgehog signaling regulates bone homeostasis through orchestrating osteoclast differentiation and osteoclast–osteoblast coupling

Cellular and molecular life sciences : CMLS, 2023-06, Vol.80 (6), p.171-171, Article 171

2023

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Circ_0001714 knockdown alleviates lipopolysaccharide-induced apoptosis and inflammation in renal tubular epithelial cells via miR-129-5p/TRAF6 axis in septic acute kidney injury

Journal of bioenergetics and biomembranes, 2023-08, Vol.55 (4), p.289-300

2023

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Long noncoding RNA LINC01234 promoted cell proliferation and invasion via miR‐1284/TRAF6 axis in colorectal cancer

Journal of cellular biochemistry, 2020-10, Vol.121 (10), p.4295-4309

2020

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MiR-146a-5p promotes IL-1β-induced chondrocyte apoptosis through the TRAF6-mediated NF-kB pathway

Inflammation research, 2020-06, Vol.69 (6), p.619-630

2020

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Regulation of glycolytic metabolism by autophagy in liver cancer involves selective autophagic degradation of HK2 (hexokinase 2)

Autophagy, 2018-04, Vol.14 (4), p.671-684

2018

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Resveratrol induces depletion of TRAF6 and suppresses prostate cancer cell proliferation and migration

The international journal of biochemistry & cell biology, 2020-01, Vol.118, p.105644-105644, Article 105644

2020

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LncRNA promoted inflammatory response in ischemic heart failure through regulation of miR-455-3p/TRAF6 axis

Inflammation research, 2020-07, Vol.69 (7), p.667-681

2020

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miR-146a-5p-modified hUCMSC-derived exosomes facilitate spinal cord function recovery by targeting neurotoxic astrocytes

Stem cell research & therapy, 2022-09, Vol.13 (1), p.1-487, Article 487

2022

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Down-regulated miR-146a expression with increased neutrophil extracellular traps and apoptosis formation in autoimmune-mediated diffuse alveolar hemorrhage

Journal of biomedical science, 2022-08, Vol.29 (1), p.1-62, Article 62

2022

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Regulation of death receptor signaling by the autophagy protein TP53INP2

The EMBO journal, 2019-05, Vol.38 (10), p.n/a

2019

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The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways

Cell reports (Cambridge), 2022-08, Vol.40 (7), p.111225-111225, Article 111225

2022

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TRAF6 inhibits colorectal cancer metastasis through regulating selective autophagic CTNNB1/β-catenin degradation and is targeted for GSK3B/GSK3β-mediated phosphorylation and degradation

Notoginsenoside R1 alleviates oxidized low-density lipoprotein-induced apoptosis, inflammatory response, and oxidative stress in HUVECS through modulation of XIST/miR-221-3p/TRAF6 axis

Inhibition of TRAF6 ubiquitin-ligase activity by PRDX1 leads to inhibition of NFKB activation and autophagy activation

Downregulation of lncRNA NEAT1 Ameliorates LPS-Induced Inflammatory Responses by Promoting Macrophage M2 Polarization via miR-125a-5p/TRAF6/TAK1 Axis

TRAF6 directs FOXP3 localization and facilitates regulatory T‐cell function through K63‐linked ubiquitination

Long non‐coding RNA MEG3 inhibits M2 macrophage polarization by activating TRAF6 via microRNA‐223 down‐regulation in viral myocarditis

Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

Cocaine-Mediated Downregulation of miR-124 Activates Microglia by Targeting KLF4 and TLR4 Signaling

Toxoplasma GRA15 limits parasite growth in IFNγ‐activated fibroblasts through TRAF ubiquitin ligases

LncRNA NEAT1 accelerates renal mesangial cell injury via modulating the miR-146b/TRAF6/NF-κB axis in lupus nephritis

The lncRNA ROR/miR-124-3p/TRAF6 axis regulated the ischaemia reperfusion injury-induced inflammatory response in human cardiac myocytes

Long non-coding RNA HCG18 promotes M1 macrophage polarization through regulating the miR-146a/TRAF6 axis, facilitating the progression of diabetic peripheral neuropathy

Neobavaisoflavone inhibits osteoclastogenesis through blocking RANKL signalling‐mediated TRAF6 and c‐Src recruitment and NF‐κB, MAPK and Akt pathways

SASH1 knockdown suppresses TRAF6 ubiquitination to regulate hemangioma progression by mediating EZH2 degradation

Hedgehog signaling regulates bone homeostasis through orchestrating osteoclast differentiation and osteoclast–osteoblast coupling

Circ_0001714 knockdown alleviates lipopolysaccharide-induced apoptosis and inflammation in renal tubular epithelial cells via miR-129-5p/TRAF6 axis in septic acute kidney injury

Long noncoding RNA LINC01234 promoted cell proliferation and invasion via miR‐1284/TRAF6 axis in colorectal cancer

MiR-146a-5p promotes IL-1β-induced chondrocyte apoptosis through the TRAF6-mediated NF-kB pathway

Regulation of glycolytic metabolism by autophagy in liver cancer involves selective autophagic degradation of HK2 (hexokinase 2)

Resveratrol induces depletion of TRAF6 and suppresses prostate cancer cell proliferation and migration

LncRNA promoted inflammatory response in ischemic heart failure through regulation of miR-455-3p/TRAF6 axis

miR-146a-5p-modified hUCMSC-derived exosomes facilitate spinal cord function recovery by targeting neurotoxic astrocytes

Down-regulated miR-146a expression with increased neutrophil extracellular traps and apoptosis formation in autoimmune-mediated diffuse alveolar hemorrhage

Regulation of death receptor signaling by the autophagy protein TP53INP2

The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways

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