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Apelin/APJ system: an emerging therapeutic target for respiratory diseases

Cellular and molecular life sciences : CMLS, 2020-08, Vol.77 (15), p.2919-2930

2020

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Structural Basis for Apelin Control of the Human Apelin Receptor

Structure (London), 2017-06, Vol.25 (6), p.858-866.e4

2017

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Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan

Cell reports (Cambridge), 2017-11, Vol.21 (6), p.1471-1480

2017

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The regulatory role of the apelin/APJ axis in scarring: Identification of upstream and downstream mechanisms

Biochimica et biophysica acta. Molecular basis of disease, 2024-04, Vol.1870 (4), p.167125-167125, Article 167125

2024

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Elabela and Apelin actions in healthy and pathological pregnancies

Cytokine & growth factor reviews, 2019-04, Vol.46, p.45-53

2019

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Apelin protects against liver X receptor-mediated steatosis through AMPK and PPARα in human and mouse hepatocytes

Cellular signalling, 2017-11, Vol.39, p.84-94

2017

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Targeting the apelin pathway as a novel therapeutic approach for cardiovascular diseases

Biochimica et biophysica acta. Molecular basis of disease, 2017-08, Vol.1863 (8), p.1942-1950

2017

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Apelin/APJ system: A critical regulator of vascular smooth muscle cell

Journal of cellular physiology, 2018-07, Vol.233 (7), p.5180-5188

2018

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Adipokine Apelin/APJ Pathway Promotes Peritoneal Dissemination of Ovarian Cancer Cells by Regulating Lipid Metabolism

Molecular cancer research, 2021-09, Vol.19 (9), p.1534-1545

2021

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Molecular determinants on extracellular loop domains that dictate interaction between β‐arrestin and human APJ receptor

FEBS letters, 2019-03, Vol.593 (6), p.634-643

2019

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Postnatal developmental expression and localization of apelin and apelin receptor protein in the ovary and uterus of mice

Molecular reproduction and development, 2023-01, Vol.90 (1), p.42-52

2023

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Apelin, APJ, and ELABELA: Role in Placental Function, Pregnancy, and Foetal Development-An Overview

Cells (Basel, Switzerland), 2021-12, Vol.11 (1), p.99

2021

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Elabela‐apelin‐12, 17, 36/APJ system promotes platelet aggregation and thrombosis via activating the PANX1‐P2X7 signaling pathway

Journal of cellular biochemistry, 2023-04, Vol.124 (4), p.586-605

2023

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Expression and localization of apelin and its receptor in the testes of diabetic mice and its possible role in steroidogenesis

Cytokine (Philadelphia, Pa.), 2021-08, Vol.144, p.155554-155554, Article 155554

2021

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Apelin/APJ system: A potential therapeutic target for endothelial dysfunction‐related diseases

Journal of cellular physiology, 2019-08, Vol.234 (8), p.12149-12160

2019

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The glycoprotein GP130 governs the surface presentation of the G protein-coupled receptor APLNR

The Journal of cell biology, 2021-09, Vol.220 (9), p.1

2021

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Comparative Study of Elabela and Apelin on Apelin Receptor Activation Through β-Arrestin Recruitment

Molecular biotechnology, 2023-03, Vol.65 (3), p.394-400

2023

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Maternal Inactivity Programs Skeletal Muscle Dysfunction in Offspring Mice by Attenuating Apelin Signaling and Mitochondrial Biogenesis

Cell reports (Cambridge), 2020-12, Vol.33 (9), p.108461-108461, Article 108461

2020

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Apelin regulates skeletal muscle adaptation to exercise in a high-intensity interval training model

American Journal of Physiology: Cell Physiology, 2024-05, Vol.326 (5), p.C1437

2024

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Function and regulation of apelin/APJ system in digestive physiology and pathology

Journal of cellular physiology, 2019-06, Vol.234 (6), p.7796-7810

2019

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Apelin Receptor Signaling Protects GT1-7 GnRH Neurons Against Oxidative Stress In Vitro

Cellular and molecular neurobiology, 2022-04, Vol.42 (3), p.753-775

2022

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Single-cell transcriptomic atlas of lung microvascular regeneration after targeted endothelial cell ablation

eLife, 2023-04, Vol.12

2023

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Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives

Cell reports (Cambridge), 2017-08, Vol.20 (9), p.2116-2130

2017

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Apelin Affects the Progression of Osteoarthritis by Regulating VEGF-Dependent Angiogenesis and miR-150-5p Expression in Human Synovial Fibroblasts

Cells (Basel, Switzerland), 2020-03, Vol.9 (3), p.594

2020

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Modulation of APLNR Signaling Is Required during the Development and Maintenance of the Hematopoietic System

Stem cell reports, 2021-04, Vol.16 (4), p.727-740

2021

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Apelin/APJ system: an emerging therapeutic target for respiratory diseases

Structural Basis for Apelin Control of the Human Apelin Receptor

Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan

The regulatory role of the apelin/APJ axis in scarring: Identification of upstream and downstream mechanisms

Elabela and Apelin actions in healthy and pathological pregnancies

Apelin protects against liver X receptor-mediated steatosis through AMPK and PPARα in human and mouse hepatocytes

Targeting the apelin pathway as a novel therapeutic approach for cardiovascular diseases

Apelin/APJ system: A critical regulator of vascular smooth muscle cell

Adipokine Apelin/APJ Pathway Promotes Peritoneal Dissemination of Ovarian Cancer Cells by Regulating Lipid Metabolism

Molecular determinants on extracellular loop domains that dictate interaction between β‐arrestin and human APJ receptor

Postnatal developmental expression and localization of apelin and apelin receptor protein in the ovary and uterus of mice

Apelin, APJ, and ELABELA: Role in Placental Function, Pregnancy, and Foetal Development-An Overview

Elabela‐apelin‐12, 17, 36/APJ system promotes platelet aggregation and thrombosis via activating the PANX1‐P2X7 signaling pathway

Expression and localization of apelin and its receptor in the testes of diabetic mice and its possible role in steroidogenesis

Apelin/APJ system: A potential therapeutic target for endothelial dysfunction‐related diseases

The glycoprotein GP130 governs the surface presentation of the G protein-coupled receptor APLNR

Comparative Study of Elabela and Apelin on Apelin Receptor Activation Through β-Arrestin Recruitment

Maternal Inactivity Programs Skeletal Muscle Dysfunction in Offspring Mice by Attenuating Apelin Signaling and Mitochondrial Biogenesis

Apelin regulates skeletal muscle adaptation to exercise in a high-intensity interval training model

Function and regulation of apelin/APJ system in digestive physiology and pathology

Apelin Receptor Signaling Protects GT1-7 GnRH Neurons Against Oxidative Stress In Vitro

Single-cell transcriptomic atlas of lung microvascular regeneration after targeted endothelial cell ablation

Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives

Apelin Affects the Progression of Osteoarthritis by Regulating VEGF-Dependent Angiogenesis and miR-150-5p Expression in Human Synovial Fibroblasts

Modulation of APLNR Signaling Is Required during the Development and Maintenance of the Hematopoietic System

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