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A mechanistic overview of translation initiation in eukaryotes

Nature structural & molecular biology, 2012-06, Vol.19 (6), p.568

2012

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Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex

Molecular cell, 2015-08, Vol.59 (3), p.399-412

2015

Volltextzugriff (PDF)

The mechanism of eukaryotic translation initiation: new insights and challenges

Cold Spring Harbor perspectives in biology, 2012-10, Vol.4 (10), p.a011544-a011544

2012

Volltextzugriff (PDF)

Maximizing the return on taxpayers' investments in fundamental biomedical research

Molecular biology of the cell, 2015-05, Vol.26 (9), p.1578-1582

2015

Volltextzugriff (PDF)

Structural Changes Enable Start Codon Recognition by the Eukaryotic Translation Initiation Complex

Cell, 2014-10, Vol.159 (3), p.597-607

2014

Volltextzugriff (PDF)

Developing a culture of safety in biomedical research training

Molecular biology of the cell, 2020-10, Vol.31 (22), p.2409-2414

2020

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The Eukaryotic Translation Initiation Factors eIF1 and eIF1A Induce an Open Conformation of the 40S Ribosome

Molecular cell, 2007-04, Vol.26 (1), p.41-50

2007

Volltextzugriff (PDF)

RNA Chaperones Exist and DEAD Box Proteins Get a Life

Cell, 2002-06, Vol.109 (7), p.797-800

Lorsch, Jon R.

2002

Volltextzugriff (PDF)

A Conformational Change in the Eukaryotic Translation Preinitiation Complex and Release of eIF1 Signal Recognition of the Start Codon

Molecular cell, 2005-01, Vol.17 (2), p.265-275

2005

Volltextzugriff (PDF)

Regulatory elements in eIF1A control the fidelity of start codon selection by modulating tRNA(i)(Met) binding to the ribosome

Genes & development, 2010-01, Vol.24 (1), p.97-110

2010

Volltextzugriff (PDF)

The 5′-7-Methylguanosine Cap on Eukaryotic mRNAs Serves Both to Stimulate Canonical Translation Initiation and to Block an Alternative Pathway

Molecular cell, 2010-09, Vol.39 (6), p.950-962

2010

Volltextzugriff (PDF)

Eukaryotic initiator tRNA: Finely tuned and ready for action

FEBS letters, 2010-01, Vol.584 (2), p.396-404

2010

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Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo

Genes & development, 2007-05, Vol.21 (10), p.1217-1230

2007

Volltextzugriff (PDF)

The C-Terminal Domain of Eukaryotic Initiation Factor 5 Promotes Start Codon Recognition by Its Dynamic Interplay with eIF1 and eIF2β

Cell reports (Cambridge), 2012-06, Vol.1 (6), p.689-702

2012

Volltextzugriff (PDF)

Ribozyme catalysis: not different, just worse

Nature structural & molecular biology, 2005-05, Vol.12 (5), p.395-402

2005

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Conserved residues in yeast initiator tRNA calibrate initiation accuracy by regulating preinitiation complex stability at the start codon

Genes & development, 2014-03, Vol.28 (5), p.502-520

2014

Volltextzugriff (PDF)

Organizing Graduate Life Sciences Education around Nodes and Connections

Cell, 2011-08, Vol.146 (4), p.506-509

2011

Volltextzugriff (PDF)

Identification and characterization of functionally critical, conserved motifs in the internal repeats and N-terminal domain of yeast translation initiation factor 4B (yeIF4B)

The Journal of biological chemistry, 2014-01, Vol.289 (3), p.1704-1722

2014

Volltextzugriff (PDF)

N‐ and C‐terminal residues of eIF1A have opposing effects on the fidelity of start codon selection

The EMBO journal, 2007-03, Vol.26 (6), p.1602-1614

2007

Volltextzugriff (PDF)

Coupled Release of Eukaryotic Translation Initiation Factors 5B and 1A from 80S Ribosomes following Subunit Joining

Molecular and Cellular Biology, 2007-03, Vol.27 (6), p.2384-2397

2007

Volltextzugriff (PDF)

The eIF1A C-terminal domain promotes initiation complex assembly, scanning and AUG selection in vivo

The EMBO journal, 2005-10, Vol.24 (20), p.3588-3601

2005

Volltextzugriff (PDF)

Genetic identification of yeast 18S rRNA residues required for efficient recruitment of initiator tRNA(Met) and AUG selection

Genes & development, 2008-08, Vol.22 (16), p.2242

2008

Volltextzugriff (PDF)

rRNA Suppressor of a Eukaryotic Translation Initiation Factor 5B/Initiation Factor 2 Mutant Reveals a Binding Site for Translational GTPases on the Small Ribosomal Subunit

Molecular and Cellular Biology, 2009-02, Vol.29 (3), p.808-821

2009

Volltextzugriff (PDF)

Uncoupling of Initiation Factor eIF5B/IF2 GTPase and Translational Activities by Mutations that Lower Ribosome Affinity

Cell, 2002-12, Vol.111 (7), p.1015-1025

2002

Volltextzugriff (PDF)

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A mechanistic overview of translation initiation in eukaryotes

Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex

The mechanism of eukaryotic translation initiation: new insights and challenges

Maximizing the return on taxpayers' investments in fundamental biomedical research

Structural Changes Enable Start Codon Recognition by the Eukaryotic Translation Initiation Complex

Developing a culture of safety in biomedical research training

The Eukaryotic Translation Initiation Factors eIF1 and eIF1A Induce an Open Conformation of the 40S Ribosome

RNA Chaperones Exist and DEAD Box Proteins Get a Life

A Conformational Change in the Eukaryotic Translation Preinitiation Complex and Release of eIF1 Signal Recognition of the Start Codon

Regulatory elements in eIF1A control the fidelity of start codon selection by modulating tRNA(i)(Met) binding to the ribosome

The 5′-7-Methylguanosine Cap on Eukaryotic mRNAs Serves Both to Stimulate Canonical Translation Initiation and to Block an Alternative Pathway

The All of Us Research Program is an opportunity to enhance the diversity of US biomedical research

Eukaryotic initiator tRNA: Finely tuned and ready for action

Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo

The C-Terminal Domain of Eukaryotic Initiation Factor 5 Promotes Start Codon Recognition by Its Dynamic Interplay with eIF1 and eIF2β

Ribozyme catalysis: not different, just worse

Conserved residues in yeast initiator tRNA calibrate initiation accuracy by regulating preinitiation complex stability at the start codon

Organizing Graduate Life Sciences Education around Nodes and Connections

Identification and characterization of functionally critical, conserved motifs in the internal repeats and N-terminal domain of yeast translation initiation factor 4B (yeIF4B)

N‐ and C‐terminal residues of eIF1A have opposing effects on the fidelity of start codon selection

Coupled Release of Eukaryotic Translation Initiation Factors 5B and 1A from 80S Ribosomes following Subunit Joining

The eIF1A C-terminal domain promotes initiation complex assembly, scanning and AUG selection in vivo

Genetic identification of yeast 18S rRNA residues required for efficient recruitment of initiator tRNA(Met) and AUG selection

rRNA Suppressor of a Eukaryotic Translation Initiation Factor 5B/Initiation Factor 2 Mutant Reveals a Binding Site for Translational GTPases on the Small Ribosomal Subunit

Uncoupling of Initiation Factor eIF5B/IF2 GTPase and Translational Activities by Mutations that Lower Ribosome Affinity

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