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High-Content siRNA Screen Reveals Global ENaC Regulators and Potential Cystic Fibrosis Therapy Targets

Cell, 2013-09, Vol.154 (6), p.1390-1400

2013

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A molecular switch in the scaffold NHERF1 enables misfolded CFTR to evade the peripheral quality control checkpoint

Science signaling, 2015-05, Vol.8 (377), p.ra48

2015

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Most F508del-CFTR Is Targeted to Degradation at an Early Folding Checkpoint and Independently of Calnexin

Molecular and Cellular Biology, 2005-06, Vol.25 (12), p.5242-5252

2005

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A central role of the endoplasmic reticulum in the cell emerges from its functional contact sites with multiple organelles

Cellular and molecular life sciences : CMLS, 2020-12, Vol.77 (23), p.4729-4745

2020

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KLF4 Acts as a wt-CFTR Suppressor through an AKT-Mediated Pathway

Cells (Basel, Switzerland), 2020-07, Vol.9 (7), p.1607

2020

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Transcription-Dependent Spatial Arrangements of CFTR and Adjacent Genes in Human Cell Nuclei

The Journal of cell biology, 2004-09, Vol.166 (6), p.815-825

2004

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Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells

Genes & development, 2007-11, Vol.21 (22), p.3006-3016

2007

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Absence of EPAC1 Signaling to Stabilize CFTR in Intestinal Organoids

Cells (Basel, Switzerland), 2022-07, Vol.11 (15), p.2295

2022

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Contribution of Casein Kinase 2 and Spleen Tyrosine Kinase to CFTR Trafficking and Protein Kinase A-Induced Activity

Molecular and Cellular Biology, 2011-11, Vol.31 (22), p.4392-4404

2011

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Rescue of Mutant CFTR Trafficking Defect by the Investigational Compound MCG1516A

Cells (Basel, Switzerland), 2022-01, Vol.11 (1), p.136

2022

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Antagonistic Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Cell Surface Expression by Protein Kinases WNK4 and Spleen Tyrosine Kinase

Molecular and Cellular Biology, 2011-10, Vol.31 (19), p.4076-4086

2011

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Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic Reticulum

Cells (Basel, Switzerland), 2019-04, Vol.8 (4), p.353

2019

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Five Percent of Normal Cystic Fibrosis Transmembrane Conductance Regulator mRNA Ameliorates the Severity of Pulmonary Disease in Cystic Fibrosis

American journal of respiratory cell and molecular biology, 2002-11, Vol.27 (5), p.619-627

2002

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The SLC26A9 inhibitor S9‐A13 provides no evidence for a role of SLC26A9 in airway chloride secretion but suggests a contribution to regulation of ASL pH and gastric proton secretion

The FASEB journal, 2022-11, Vol.36 (11), p.e22534-n/a

2022

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Mutant CFTR Drives TWIST1 mediated epithelial-mesenchymal transition

Cell death & disease, 2020-10, Vol.11 (10), p.920-920, Article 920

2020

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A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic

Biochimica et biophysica acta. Molecular cell research, 2018-02, Vol.1865 (2), p.421-431

2018

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Proteomic interaction profiling reveals KIFC1 as a factor involved in early targeting of F508del-CFTR to degradation

Cellular and molecular life sciences : CMLS, 2018-12, Vol.75 (24), p.4495-4509

2018

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LMTK2-mediated Phosphorylation Regulates CFTR Endocytosis in Human Airway Epithelial Cells

The Journal of biological chemistry, 2014-05, Vol.289 (21), p.15080-15093

2014

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The third dimension: new developments in cell culture models for colorectal research

Cellular and molecular life sciences : CMLS, 2016-11, Vol.73 (21), p.3971-3989

2016

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CFTR gene transfer to human cystic fibrosis pancreatic duct cells using a Sendai virus vector

Journal of cellular physiology, 2008-02, Vol.214 (2), p.442-455

2008

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Organoids as a personalized medicine tool for ultra-rare mutations in cystic fibrosis: The case of S955P and 1717-2A>G

Biochimica et biophysica acta. Molecular basis of disease, 2020-11, Vol.1866 (11), p.165905-165905, Article 165905

2020

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AMPK controls epithelial Na+ channels through Nedd4-2 and causes an epithelial phenotype when mutated

Pflügers Archiv, 2009-08, Vol.458 (4), p.713-721

2009

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Regulation of ENaC biogenesis by the stress response protein SERP1

Pflügers Archiv, 2012-06, Vol.463 (6), p.819-827

2012

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BAG-1 Stabilizes Mutant F508del-CFTR in a Ubiquitin-Like-Domain-Dependent Manner

Cellular physiology and biochemistry, 2012-01, Vol.30 (5), p.1120-1133

2012

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Deletion of CFTR Translation Start Site Reveals Functional Isoforms of the Protein in CF Patients

Cellular physiology and biochemistry, 2009-01, Vol.24 (5-6), p.335-346

2009

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High-Content siRNA Screen Reveals Global ENaC Regulators and Potential Cystic Fibrosis Therapy Targets

A molecular switch in the scaffold NHERF1 enables misfolded CFTR to evade the peripheral quality control checkpoint

Most F508del-CFTR Is Targeted to Degradation at an Early Folding Checkpoint and Independently of Calnexin

A central role of the endoplasmic reticulum in the cell emerges from its functional contact sites with multiple organelles

KLF4 Acts as a wt-CFTR Suppressor through an AKT-Mediated Pathway

Transcription-Dependent Spatial Arrangements of CFTR and Adjacent Genes in Human Cell Nuclei

Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells

Absence of EPAC1 Signaling to Stabilize CFTR in Intestinal Organoids

Contribution of Casein Kinase 2 and Spleen Tyrosine Kinase to CFTR Trafficking and Protein Kinase A-Induced Activity

Rescue of Mutant CFTR Trafficking Defect by the Investigational Compound MCG1516A

Antagonistic Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Cell Surface Expression by Protein Kinases WNK4 and Spleen Tyrosine Kinase

Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic Reticulum

Five Percent of Normal Cystic Fibrosis Transmembrane Conductance Regulator mRNA Ameliorates the Severity of Pulmonary Disease in Cystic Fibrosis

The SLC26A9 inhibitor S9‐A13 provides no evidence for a role of SLC26A9 in airway chloride secretion but suggests a contribution to regulation of ASL pH and gastric proton secretion

Mutant CFTR Drives TWIST1 mediated epithelial-mesenchymal transition

A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic

Proteomic interaction profiling reveals KIFC1 as a factor involved in early targeting of F508del-CFTR to degradation

LMTK2-mediated Phosphorylation Regulates CFTR Endocytosis in Human Airway Epithelial Cells

The third dimension: new developments in cell culture models for colorectal research

CFTR gene transfer to human cystic fibrosis pancreatic duct cells using a Sendai virus vector

Organoids as a personalized medicine tool for ultra-rare mutations in cystic fibrosis: The case of S955P and 1717-2A>G

AMPK controls epithelial Na+ channels through Nedd4-2 and causes an epithelial phenotype when mutated

Regulation of ENaC biogenesis by the stress response protein SERP1

BAG-1 Stabilizes Mutant F508del-CFTR in a Ubiquitin-Like-Domain-Dependent Manner

Deletion of CFTR Translation Start Site Reveals Functional Isoforms of the Protein in CF Patients

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