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CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity

Immunity (Cambridge, Mass.), 2018-10, Vol.49 (4), p.678-694.e5

2018

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Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection

Nature immunology, 2013-06, Vol.14 (6), p.574-583

2013

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The Transcription Factor TCF1 Preserves the Effector Function of Exhausted CD8 T Cells During Chronic Viral Infection

Frontiers in immunology, 2019-02, Vol.10, p.169-169

2019

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Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent

Science (American Association for the Advancement of Science), 2017-03, Vol.355 (6332), p.1423-1427

2017

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The epigenetic landscape of T cell exhaustion

Science (American Association for the Advancement of Science), 2016-12, Vol.354 (6316), p.1165-1169

2016

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Chronic virus infection drives CD8 T cell-mediated thymic destruction and impaired negative selection

Proceedings of the National Academy of Sciences - PNAS, 2020-03, Vol.117 (10), p.5420-5429

2020

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PSGL-1 Is a T Cell Intrinsic Inhibitor That Regulates Effector and Memory Differentiation and Responses During Viral Infection

Frontiers in immunology, 2021-07, Vol.12, p.677824-677824

2021

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CD8 T Cell Exhaustion in Chronic Infection and Cancer: Opportunities for Interventions

Annual review of medicine, 2018-01, Vol.69 (1), p.301-318

2018

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Anti-PD-L1 Immunotherapy of Chronic Virus Infection Improves Virus Control without Augmenting Tissue Damage by Fibrosis

Viruses, 2024-05, Vol.16 (5), p.799

2024

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PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program

Nature (London), 2022-10, Vol.610 (7930), p.173-181

2022

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Anti-GITR agonist therapy intrinsically enhances CD8 T cell responses to chronic lymphocytic choriomeningitis virus (LCMV), thereby circumventing LCMV-induced downregulation of costimulatory GITR ligand on APC

The Journal of immunology (1950), 2014-11, Vol.193 (10), p.5033-5043

2014

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Platinum-Based Chemotherapy Attenuates the Effector Response of CD8 T Cells to Concomitant PD-1 Blockade

Clinical cancer research, 2024-05, Vol.30 (9), p.1833-1845

2024

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PD-L1 Checkpoint Inhibition Narrows the Antigen-Specific T Cell Receptor Repertoire in Chronic Lymphocytic Choriomeningitis Virus Infection

Journal of virology, 2020-08, Vol.94 (18)

2020

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Low CD8 T-Cell Proliferative Potential and High Viral Load Limit the Effectiveness of Therapeutic Vaccination

Journal of Virology, 2005-07, Vol.79 (14), p.8960-8968

2005

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Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo

Nature medicine, 2003-05, Vol.9 (5), p.540-547

2003

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Lymphocytic choriomeningitis infection of the central nervous system

Frontiers in bioscience, 2008-05, Vol.13 (13), p.4529

2008

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Cyclophilin D Regulates Antiviral CD8 + T Cell Survival in a Cell-Extrinsic Manner

ImmunoHorizons, 2020-04, Vol.4 (4), p.217-230

2020

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Vectored antibody gene delivery restores host B and T cell control of persistent viral infection

Cell reports (Cambridge), 2021-11, Vol.37 (9), p.110061-110061, Article 110061

2021

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PD-1 Immune Checkpoint Blockade and PSGL-1 Inhibition Synergize to Reinvigorate Exhausted T Cells

Frontiers in immunology, 2022-06, Vol.13, p.869768-869768

2022

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n -3 Polyunsaturated Fatty Acids Impede the TCR Mobility and the TCR-pMHC Interaction of Anti-Viral CD8+ T Cells

Viruses, 2020-06, Vol.12 (6), p.639

2020

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Efficacy of IL-2- versus IL-15-stimulated CD8 T cells in adoptive immunotherapy

European journal of immunology, 2008-10, Vol.38 (10), p.2874-2885

2008

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Au-ACRAMTU-PEt3 Alters Redox Balance To Inhibit T Cell Proliferation and Function

The Journal of immunology (1950), 2015-09, Vol.195 (5), p.1984-1994

2015

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Therapeutic Memory T Cells Require Costimulation for Effective Clearance of a Persistent Viral Infection

Journal of Virology, 2009-09, Vol.83 (17), p.8905-8915

2009

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Immunotherapeutic effects of IL-7 during a chronic viral infection in mice

Blood, 2011-05, Vol.117 (19), p.5123-5132

2011

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Effects of IL-7 on memory CD8 T cell homeostasis are influenced by the timing of therapy in mice

The Journal of clinical investigation, 2008-03, Vol.118 (3), p.1027-1039

2008

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CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity

Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection

The Transcription Factor TCF1 Preserves the Effector Function of Exhausted CD8 T Cells During Chronic Viral Infection

Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent

The epigenetic landscape of T cell exhaustion

Chronic virus infection drives CD8 T cell-mediated thymic destruction and impaired negative selection

PSGL-1 Is a T Cell Intrinsic Inhibitor That Regulates Effector and Memory Differentiation and Responses During Viral Infection

CD8 T Cell Exhaustion in Chronic Infection and Cancer: Opportunities for Interventions

Anti-PD-L1 Immunotherapy of Chronic Virus Infection Improves Virus Control without Augmenting Tissue Damage by Fibrosis

PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program

Anti-GITR agonist therapy intrinsically enhances CD8 T cell responses to chronic lymphocytic choriomeningitis virus (LCMV), thereby circumventing LCMV-induced downregulation of costimulatory GITR ligand on APC

Platinum-Based Chemotherapy Attenuates the Effector Response of CD8 T Cells to Concomitant PD-1 Blockade

PD-L1 Checkpoint Inhibition Narrows the Antigen-Specific T Cell Receptor Repertoire in Chronic Lymphocytic Choriomeningitis Virus Infection

Low CD8 T-Cell Proliferative Potential and High Viral Load Limit the Effectiveness of Therapeutic Vaccination

Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo

Lymphocytic choriomeningitis infection of the central nervous system

Cyclophilin D Regulates Antiviral CD8 + T Cell Survival in a Cell-Extrinsic Manner

Vectored antibody gene delivery restores host B and T cell control of persistent viral infection

PD-1 Immune Checkpoint Blockade and PSGL-1 Inhibition Synergize to Reinvigorate Exhausted T Cells

n -3 Polyunsaturated Fatty Acids Impede the TCR Mobility and the TCR-pMHC Interaction of Anti-Viral CD8+ T Cells

Efficacy of IL-2- versus IL-15-stimulated CD8 T cells in adoptive immunotherapy

Au-ACRAMTU-PEt3 Alters Redox Balance To Inhibit T Cell Proliferation and Function

Therapeutic Memory T Cells Require Costimulation for Effective Clearance of a Persistent Viral Infection

Immunotherapeutic effects of IL-7 during a chronic viral infection in mice

Effects of IL-7 on memory CD8 T cell homeostasis are influenced by the timing of therapy in mice

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