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TNFα transport induced by dynamic loading alters biomechanics of intact intervertebral discs

PloS one, 2015-03, Vol.10 (3), p.e0118358-e0118358

2015

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SLRP interaction can protect collagen fibrils from cleavage by collagenases

Matrix biology, 2006-10, Vol.25 (8), p.484-491

2006

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MMPs are less efficient than ADAMTS5 in cleaving aggrecan core protein

Matrix biology, 2011-03, Vol.30 (2), p.145-153

2011

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Physiological loading can restore the proteoglycan content in a model of early IVD degeneration

PloS one, 2014-07, Vol.9 (7), p.e101233-e101233

2014

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Tumor necrosis factorα modulates matrix production and catabolism in nucleus pulposus tissue

Spine (Philadelphia, Pa. 1976), 2005-09, Vol.30 (17), p.1940-1948

2005

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Detrimental effects of discectomy on intervertebral disc biology can be decelerated by growth factor treatment during surgery: a large animal organ culture model

The spine journal, 2014-11, Vol.14 (11), p.2724-2732

2014

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The Effects of Chlorhexidine Graft Decontamination on Tendon Graft Collagen and Cell Viability

The American journal of sports medicine, 2012-07, Vol.40 (7), p.1646-1653

2012

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The mechanism of aggrecan release from cartilage differs with tissue origin and the agent used to stimulate catabolism

Biochemical journal, 2002-03, Vol.362 (Pt 2), p.465-472

2002

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Improved bioengineered cartilage tissue formation following cyclic compression is dependent on upregulation of MT1-MMP

Journal of orthopaedic research, 2010-07, Vol.28 (7), p.921-927

2010

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Peptides of type II collagen can induce the cleavage of type II collagen and aggrecan in articular cartilage

Matrix biology, 2006-09, Vol.25 (7), p.419-429

2006

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Measurement of glycosaminoglycan release from cartilage explants

Methods in molecular medicine, 2007, Vol.135, p.201

2007

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Lumican inhibits collagen deposition in tissue engineered cartilage

Matrix biology, 2008-07, Vol.27 (6), p.526-534

2008

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Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro

Biochemical journal, 1999-11, Vol.344 Pt 1 (1), p.61-68

1999

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Development of an intact intervertebral disc organ culture system in which degeneration can be induced as a prelude to studying repair potential

European spine journal, 2011-08, Vol.20 (8), p.1244-1254

2011

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Effect of oxygen levels on proteoglycan synthesis by intervertebral disc cells

Spine (Philadelphia, Pa. 1976), 2011-01, Vol.36 (2), p.E131-E138

2011

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Link N and mesenchymal stem cells can induce regeneration of the early degenerate intervertebral disc

Tissue engineering. Part A, 2014-11, Vol.20 (21-22), p.2942-2949

2014

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Variations in aggrecan structure modulate its susceptibility to aggrecanases

Biochemical journal, 2003-10, Vol.375 (Pt 1), p.183-189

2003

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The potential of chitosan-based gels containing intervertebral disc cells for nucleus pulposus supplementation

Biomaterials, 2006, Vol.27 (3), p.388-396

2006

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Chemical and Immunological Assay of the Nonreducing Terminal Residues of Chondroitin Sulfate from Human Aggrecan

The Journal of biological chemistry, 1997-08, Vol.272 (33), p.20603-20610

1997

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Best paper NASS 2013: link-N can stimulate proteoglycan synthesis in the degenerated human intervertebral discs

European Cells and Materials, 2013-09, Vol.26, p.107-119

2013

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Insect cell conditioned medium contains an endoglycosidase able to liberate chondroitin sulfate chains from aggrecan

Matrix biology, 2005-08, Vol.24 (5), p.371-375

2005

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Age-Related changes in cartilage proteoglycans: Quantitative electron microscopic studies

Microscopy research and technique, 1994-08, Vol.28 (5), p.398-408

1994

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The potential and limitations of a cell-seeded collagen/hyaluronan scaffold to engineer an intervertebral disc-like matrix

Spine (Philadelphia, Pa. 1976), 2003-03, Vol.28 (5), p.446-453

2003

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Link N is cleaved by human annulus fibrosus cells generating a fragment with retained biological activity

Journal of orthopaedic research, 2014-09, Vol.32 (9), p.1189-1197

2014

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Development of a bioreactor for axially loaded intervertebral disc organ culture

Tissue engineering. Part C, Methods, 2011-10, Vol.17 (10), p.1011-1019

2011

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TNFα transport induced by dynamic loading alters biomechanics of intact intervertebral discs

SLRP interaction can protect collagen fibrils from cleavage by collagenases

MMPs are less efficient than ADAMTS5 in cleaving aggrecan core protein

Physiological loading can restore the proteoglycan content in a model of early IVD degeneration

Tumor necrosis factorα modulates matrix production and catabolism in nucleus pulposus tissue

Detrimental effects of discectomy on intervertebral disc biology can be decelerated by growth factor treatment during surgery: a large animal organ culture model

The Effects of Chlorhexidine Graft Decontamination on Tendon Graft Collagen and Cell Viability

The mechanism of aggrecan release from cartilage differs with tissue origin and the agent used to stimulate catabolism

Improved bioengineered cartilage tissue formation following cyclic compression is dependent on upregulation of MT1-MMP

Peptides of type II collagen can induce the cleavage of type II collagen and aggrecan in articular cartilage

Measurement of glycosaminoglycan release from cartilage explants

Lumican inhibits collagen deposition in tissue engineered cartilage

Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro

Development of an intact intervertebral disc organ culture system in which degeneration can be induced as a prelude to studying repair potential

Effect of oxygen levels on proteoglycan synthesis by intervertebral disc cells

Link N and mesenchymal stem cells can induce regeneration of the early degenerate intervertebral disc

Variations in aggrecan structure modulate its susceptibility to aggrecanases

The potential of chitosan-based gels containing intervertebral disc cells for nucleus pulposus supplementation

Chemical and Immunological Assay of the Nonreducing Terminal Residues of Chondroitin Sulfate from Human Aggrecan

Best paper NASS 2013: link-N can stimulate proteoglycan synthesis in the degenerated human intervertebral discs

Insect cell conditioned medium contains an endoglycosidase able to liberate chondroitin sulfate chains from aggrecan

Age-Related changes in cartilage proteoglycans: Quantitative electron microscopic studies

The potential and limitations of a cell-seeded collagen/hyaluronan scaffold to engineer an intervertebral disc-like matrix

Link N is cleaved by human annulus fibrosus cells generating a fragment with retained biological activity

Development of a bioreactor for axially loaded intervertebral disc organ culture

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