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Eribulin Binds at Microtubule Ends to a Single Site on Tubulin To Suppress Dynamic Instability

Biochemistry (Easton), 2010-02, Vol.49 (6), p.1331-1337

2010

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The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth

Molecular cancer therapeutics, 2005-07, Vol.4 (7), p.1086-1095

2005

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2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules

Molecular cancer therapeutics, 2006-09, Vol.5 (9), p.2225-2233

2006

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Substoichiometric Binding of Taxol Suppresses Microtubule Dynamics

Biochemistry (Easton), 1995-02, Vol.34 (7), p.2203-2211

1995

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Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules

Molecular cancer therapeutics, 2010-10, Vol.9 (10), p.2689-2699

2010

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Mechanism of action of ixabepilone and its interactions with the βIII-tubulin isotype

Cancer chemotherapy and pharmacology, 2015-11, Vol.76 (5), p.1013-1024

2015

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Intrinsically Slow Dynamic Instability of HeLa Cell Microtubules in Vitro

The Journal of biological chemistry, 2002-11, Vol.277 (45), p.42456-42462

2002

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Differential Effects of Vinblastine on Polymerization and Dynamics at Opposite Microtubule Ends

The Journal of biological chemistry, 1996-11, Vol.271 (47), p.29807-29812

1996

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Kinetic stabilization of microtubule dynamic instability in vitro by vinblastine

Biochemistry (Easton), 1993-02, Vol.32 (5), p.1285-1293

1993

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Effects of Eribulin on Microtubule Binding and Dynamic Instability Are Strengthened in the Absence of the βIII Tubulin Isotype

Biochemistry (Easton), 2015-10, Vol.54 (42), p.6482-6489

2015

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βIII-tubulin enhances efficacy of cabazitaxel as compared with docetaxel

Cancer chemotherapy and pharmacology, 2017-07, Vol.80 (1), p.151-164

2017

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Kinetic Stabilization of Microtubule Dynamics at Steady State in Vitro by Substoichiometric Concentrations of Tubulin-Colchicine Complex

Biochemistry (Easton), 1995-08, Vol.34 (31), p.9921-9929

1995

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Inhibition of Mitosis and Microtubule Function through Direct Tubulin Binding by a Novel Antiproliferative Naphthopyran LY290181

Molecular pharmacology, 1997-09, Vol.52 (3), p.437-444

1997

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Mechanism of action of the microtubule-targeted antimitotic depsipeptide tasidotin (Formerly ILX651) and its major metabolite tasidotin C-carboxylate

Cancer research (Chicago, Ill.), 2007-04, Vol.67 (8), p.3767-3776

2007

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The neuroprotective peptide NAP does not directly affect polymerization or dynamics of reconstituted neural microtubules

Journal of Alzheimer's disease, 2010-01, Vol.19 (4), p.1377-1386

2010

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Three- and four-repeat tau regulate the dynamic instability of two distinct microtubule subpopulations in qualitatively different manners. Implications for neurodegeneration

The Journal of biological chemistry, 2005-04, Vol.280 (14), p.13520-13528

2005

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Mechanism of Mitotic Block and Inhibition of Cell Proliferation by Taxol at Low Concentrations

Proceedings of the National Academy of Sciences - PNAS, 1993-10, Vol.90 (20), p.9552-9556

1993

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Microtubule Assembly of Isotypically Purified Tubulin and Its Mixtures

Biophysical journal, 2008-08, Vol.95 (4), p.1993-2008

2008

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Taxol Differentially Modulates the Dynamics of Microtubules Assembled from Unfractionated and Purified β-Tubulin Isotypes

Biochemistry (Easton), 1997-03, Vol.36 (12), p.3554-3562

1997

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Interaction of the Antitumor Compound Cryptophycin-52 with Tubulin

Biochemistry (Easton), 2000-11, Vol.39 (46), p.14121-14127

2000

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Mechanism of Action of the Unusually Potent Microtubule Inhibitor Cryptophycin 1

Biochemistry (Easton), 1997-10, Vol.36 (42), p.12948-12953

1997

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Suppression of Microtubule Dynamics by Binding of Cemadotin to Tubulin: Possible Mechanism for Its Antitumor Action

Biochemistry (Easton), 1998-12, Vol.37 (50), p.17571-17578

1998

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Low potency of Taxol at microtubule minus ends : Implications for its antimitotic and therapeutic mechanism

Cancer research (Chicago, Ill.), 1998-03, Vol.58 (6), p.1177-1184

1998

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Kinetic analysis of tubulin exchange at microtubule ends at low vinblastine concentrations

Biochemistry (Easton), 1990-03, Vol.29 (11), p.2730-2739

1990

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Comparison of the effects of vinblastine, vincristine, vindesine, and vinepidine on microtubule dynamics and cell proliferation in vitro

Cancer research (Chicago, Ill.), 1985-06, Vol.45 (6), p.2741-2747

1985

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Eribulin Binds at Microtubule Ends to a Single Site on Tubulin To Suppress Dynamic Instability

The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth

2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules

Substoichiometric Binding of Taxol Suppresses Microtubule Dynamics

Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules

Mechanism of action of ixabepilone and its interactions with the βIII-tubulin isotype

Intrinsically Slow Dynamic Instability of HeLa Cell Microtubules in Vitro

Differential Effects of Vinblastine on Polymerization and Dynamics at Opposite Microtubule Ends

Kinetic stabilization of microtubule dynamic instability in vitro by vinblastine

Effects of Eribulin on Microtubule Binding and Dynamic Instability Are Strengthened in the Absence of the βIII Tubulin Isotype

βIII-tubulin enhances efficacy of cabazitaxel as compared with docetaxel

Kinetic Stabilization of Microtubule Dynamics at Steady State in Vitro by Substoichiometric Concentrations of Tubulin-Colchicine Complex

Inhibition of Mitosis and Microtubule Function through Direct Tubulin Binding by a Novel Antiproliferative Naphthopyran LY290181

Mechanism of action of the microtubule-targeted antimitotic depsipeptide tasidotin (Formerly ILX651) and its major metabolite tasidotin C-carboxylate

The neuroprotective peptide NAP does not directly affect polymerization or dynamics of reconstituted neural microtubules

Three- and four-repeat tau regulate the dynamic instability of two distinct microtubule subpopulations in qualitatively different manners. Implications for neurodegeneration

Mechanism of Mitotic Block and Inhibition of Cell Proliferation by Taxol at Low Concentrations

Microtubule Assembly of Isotypically Purified Tubulin and Its Mixtures

Taxol Differentially Modulates the Dynamics of Microtubules Assembled from Unfractionated and Purified β-Tubulin Isotypes

Interaction of the Antitumor Compound Cryptophycin-52 with Tubulin

Mechanism of Action of the Unusually Potent Microtubule Inhibitor Cryptophycin 1

Suppression of Microtubule Dynamics by Binding of Cemadotin to Tubulin: Possible Mechanism for Its Antitumor Action

Low potency of Taxol at microtubule minus ends : Implications for its antimitotic and therapeutic mechanism

Kinetic analysis of tubulin exchange at microtubule ends at low vinblastine concentrations

Comparison of the effects of vinblastine, vincristine, vindesine, and vinepidine on microtubule dynamics and cell proliferation in vitro

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