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Stepwise Reversion of Multiply Mutated Recombinant Antitrypsin Reveals a Selective Inhibitor of Coagulation Factor XIa as Active as the M358R Variant

Frontiers in cardiovascular medicine, 2021-03, Vol.8, p.647405

2021

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Factor VIIa gets even bigger

Thrombosis and haemostasis, 2008-04, Vol.99 (4), p.653-654

2008

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Recombinant albumins containing additional peptide sequences smaller than barbourin retain the ability of barbourin-albumin to inhibit platelet aggregation

Thrombosis and haemostasis, 2005-05, Vol.93 (5), p.914-921

2005

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Alpha-1 proteinase inhibitor M358R reduces thrombin generation when displayed on the surface of cells expressing tissue factor

Thrombosis research, 2014-11, Vol.134 (5), p.1142-1149

2014

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Altering heparin cofactor II at VAL439 (P6) either impairs inhibition of thrombin or confers elastase resistance

Thrombosis and haemostasis, 2002-07, Vol.88 (1), p.89-97

2002

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Alpha-1 Acid Glycoprotein Reduces Hepatic Leukocyte Recruitment in Murine Models of Either Early Endotoxemia or Early Sepsis

Microcirculation (New York, N.Y. 1994), 2014-01, Vol.21 (1), p.74-83

2014

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Modulation of Clearance of Recombinant Serum Albumin by Either Glycosylation or Truncation

Thrombosis research, 2000-09, Vol.99 (6), p.613-621

2000

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Investigating serpin–enzyme complex formation and stability via single and multiple residue reactive centre loop substitutions in heparin cofactor II

Thrombosis research, 2006, Vol.117 (4), p.447-461

2006

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A barbourin-albumin fusion protein that is slowly cleared in vivo retains the ability to inhibit platelet aggregation in vitro

Thrombosis and haemostasis, 2001-09, Vol.86 (3), p.902-908

2001

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The clearance of thrombin-antithrombin and related serpin-enzyme complexes from the circulation: role of various hepatocyte receptors

Thrombosis and haemostasis, 1999-03, Vol.81 (3), p.325-337

1999

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Heparin cofactor II is more sensitive than antithrombin to secretory impairment arising from mutations introduced into its carboxy-terminal region

Thrombosis research, 2004, Vol.113 (2), p.163-173

2004

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Mutation of Any Site of N-Linked Glycosylation Accelerates the In Vivo Clearance of Recombinant Rabbit Antithrombin

Thrombosis research, 2000-08, Vol.99 (4), p.407-415

2000

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IMPACT OF MUTATIONS AT THE P4 AND P5 POSITIONS ON THE REACTION OF ANTITHROMBIN WITH THROMBIN AND ELASTASE

Thrombosis research, 1997-10, Vol.88 (2), p.171-181

1997

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INHIBITION OF THROMBIN BY HIRUDIN GENETICALLY FUSED TO WILD-TYPE OR MUTANT ANTITHROMBIN

Thrombosis research, 1996-12, Vol.84 (6), p.419-429

1996

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Molecular cloning and expression of rabbit heparin cofactor II: a plasma thrombin inhibitor highly conserved between species

Thrombosis and haemostasis, 1994-06, Vol.71 (6), p.778-782

1994

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Amino acid substitutions of the P2 residue of human antithrombin that either enhance or impair function

Thrombosis research, 1994-08, Vol.75 (3), p.293-305

1994

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Molecular cloning and cell-free expression of mouse antithrombin III

Thrombosis and haemostasis, 1992-09, Vol.68 (3), p.291-296

1992

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Complete nucleotide sequence of the cdna encoding rabbit coagulation factor VII

Thrombosis research, 1993-01, Vol.69 (2), p.231-238

1993

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Characterization of a highly polymorphic trinucleotide short tandem repeat within the human antithrombin gene

Thrombosis research, 1994-05, Vol.74 (3), p.303-307

1994

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Sex differences in chest pain in patients with documented coronary artery disease and exercise-induced ischemia: Results from the PIMI study

The American heart journal, 2001-11, Vol.142 (5), p.864-871

2001

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Quality of life among 5,025 patients with left ventricular dysfunction randomized between placebo and enalapril: The studies of left ventricular dysfunction

Journal of the American College of Cardiology, 1994-02, Vol.23 (2), p.393-400

1994

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Low hot pain threshold predicts shorter time to exercise-induced angina: results from the psychophysiological investigations of myocardial ischemia (PIMI) study

Journal of the American College of Cardiology, 1999-06, Vol.33 (7), p.1855-1862

1999

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Stepwise Reversion of Multiply Mutated Recombinant Antitrypsin Reveals a Selective Inhibitor of Coagulation Factor XIa as Active as the M358R Variant

Factor VIIa gets even bigger

Recombinant albumins containing additional peptide sequences smaller than barbourin retain the ability of barbourin-albumin to inhibit platelet aggregation

Alpha-1 proteinase inhibitor M358R reduces thrombin generation when displayed on the surface of cells expressing tissue factor

Altering heparin cofactor II at VAL439 (P6) either impairs inhibition of thrombin or confers elastase resistance

Alpha-1 Acid Glycoprotein Reduces Hepatic Leukocyte Recruitment in Murine Models of Either Early Endotoxemia or Early Sepsis

Modulation of Clearance of Recombinant Serum Albumin by Either Glycosylation or Truncation

Investigating serpin–enzyme complex formation and stability via single and multiple residue reactive centre loop substitutions in heparin cofactor II

A barbourin-albumin fusion protein that is slowly cleared in vivo retains the ability to inhibit platelet aggregation in vitro

The clearance of thrombin-antithrombin and related serpin-enzyme complexes from the circulation: role of various hepatocyte receptors

Heparin cofactor II is more sensitive than antithrombin to secretory impairment arising from mutations introduced into its carboxy-terminal region

Mutation of Any Site of N-Linked Glycosylation Accelerates the In Vivo Clearance of Recombinant Rabbit Antithrombin

IMPACT OF MUTATIONS AT THE P4 AND P5 POSITIONS ON THE REACTION OF ANTITHROMBIN WITH THROMBIN AND ELASTASE

INHIBITION OF THROMBIN BY HIRUDIN GENETICALLY FUSED TO WILD-TYPE OR MUTANT ANTITHROMBIN

Molecular cloning and expression of rabbit heparin cofactor II: a plasma thrombin inhibitor highly conserved between species

Amino acid substitutions of the P2 residue of human antithrombin that either enhance or impair function

Molecular cloning and cell-free expression of mouse antithrombin III

Complete nucleotide sequence of the cdna encoding rabbit coagulation factor VII

Characterization of a highly polymorphic trinucleotide short tandem repeat within the human antithrombin gene

Sex differences in chest pain in patients with documented coronary artery disease and exercise-induced ischemia: Results from the PIMI study

Quality of life among 5,025 patients with left ventricular dysfunction randomized between placebo and enalapril: The studies of left ventricular dysfunction

Low hot pain threshold predicts shorter time to exercise-induced angina: results from the psychophysiological investigations of myocardial ischemia (PIMI) study

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