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Tumor―Stroma Interaction: Revealing Fibroblast-Secreted Exosomes as Potent Regulators of Wnt-Planar Cell Polarity Signaling in Cancer Metastasis

Cancer research (Chicago, Ill.), 2013-12, Vol.73 (23), p.6843-6847

2013

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A Late Transition in Somatic Cell Reprogramming Requires Regulators Distinct from the Pluripotency Network

Cell stem cell, 2012-12, Vol.11 (6), p.769-782

2012

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The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway

Developmental cell, 2010-12, Vol.19 (6), p.831-844

2010

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Dynamic modularity in protein interaction networks predicts breast cancer outcome

Nature biotechnology, 2009-02, Vol.27 (2), p.199-204

2009

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Image-based genome-wide siRNA screen identifies selective autophagy factors

Nature (London), 2011-12, Vol.480 (7375), p.113-117

2011

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Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming

Cell stem cell, 2010-07, Vol.7 (1), p.64-77

2010

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The Hippo Pathway Regulates Wnt/β-Catenin Signaling

Developmental cell, 2010-04, Vol.18 (4), p.579-591

2010

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Regulation of the Polarity Protein Par6 by TGFβ Receptors Controls Epithelial Cell Plasticity

Science (American Association for the Advancement of Science), 2005-03, Vol.307 (5715), p.1603-1609

2005

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Regulation of Cytokine Receptors by Golgi N-Glycan Processing and Endocytosis

Science (American Association for the Advancement of Science), 2004-10, Vol.306 (5693), p.120-124

2004

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High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells

Science (American Association for the Advancement of Science), 2005-03, Vol.307 (5715), p.1621-1625

2005

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Regulation of Cell Polarity and Protrusion Formation by Targeting RhoA for Degradation

Science (American Association for the Advancement of Science), 2003-12, Vol.302 (5651), p.1775-1779

2003

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Small Molecule Kinase Inhibitor Screen Identifies Polo-Like Kinase 1 as a Target for Neuroblastoma Tumor-Initiating Cells

Cancer research (Chicago, Ill.), 2011-02, Vol.71 (4), p.1385-1395

2011

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A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

Nature (London), 1999-08, Vol.400 (6745), p.687-693

1999

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Inhibition of the Sodium Potassium Adenosine Triphosphatase Pump Sensitizes Cancer Cells to Anoikis and Prevents Distant Tumor Formation

Cancer research (Chicago, Ill.), 2009-04, Vol.69 (7), p.2739-2747

2009

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Slit Receptor EVA-1 Coactivates a SAX-3/Robo-Mediated Guidance Signal in C. elegans

Science (American Association for the Advancement of Science), 2007-09, Vol.317 (5846), p.1934-1938

2007

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C4ST-1/CHST11-controlled chondroitin sulfation interferes with oncogenic HRAS signaling in Costello syndrome

European journal of human genetics : EJHG, 2012-08, Vol.20 (8), p.870-877

2012

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Mechanism of activation of the TGF-β receptor

Nature (London), 1994-08, Vol.370 (6488), p.341-347

1994

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Structural Basis of Smad2 Recognition by the Smad Anchor for Receptor Activation

Science (American Association for the Advancement of Science), 2000-01, Vol.287 (5450), p.92-97

2000

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Next-generation RNA Sequencing of Archival Formalin-fixed Paraffin-embedded Urothelial Bladder Cancer

European urology, 2014-12, Vol.66 (6), p.982-986

2014

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Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain

Bioorganic & medicinal chemistry letters, 2011-09, Vol.21 (18), p.5605-5609

2011

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Signaling and Endocytosis: A Team Effort for Cell Migration

Developmental cell, 2005-08, Vol.9 (2), p.167-168

2005

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Genome-Wide Identification of Smad/Foxh1 Targets Reveals a Role for Foxh1 in Retinoic Acid Regulation and Forebrain Development

Developmental cell, 2008-03, Vol.14 (3), p.411-423

2008

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A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesis

Cancer research (Chicago, Ill.), 2007-09, Vol.67 (17), p.8307-8315

2007

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The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development

Nature (London), 1993-10, Vol.365 (6447), p.644-649

1993

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Chemical enhancers of cytokine signaling that suppress microfilament turnover and tumor cell growth

Cancer research (Chicago, Ill.), 2006-04, Vol.66 (7), p.3558-3566

2006

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Tumor―Stroma Interaction: Revealing Fibroblast-Secreted Exosomes as Potent Regulators of Wnt-Planar Cell Polarity Signaling in Cancer Metastasis

A Late Transition in Somatic Cell Reprogramming Requires Regulators Distinct from the Pluripotency Network

The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway

Dynamic modularity in protein interaction networks predicts breast cancer outcome

Image-based genome-wide siRNA screen identifies selective autophagy factors

Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming

The Hippo Pathway Regulates Wnt/β-Catenin Signaling

Regulation of the Polarity Protein Par6 by TGFβ Receptors Controls Epithelial Cell Plasticity

Regulation of Cytokine Receptors by Golgi N-Glycan Processing and Endocytosis

High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells

Regulation of Cell Polarity and Protrusion Formation by Targeting RhoA for Degradation

Small Molecule Kinase Inhibitor Screen Identifies Polo-Like Kinase 1 as a Target for Neuroblastoma Tumor-Initiating Cells

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

Inhibition of the Sodium Potassium Adenosine Triphosphatase Pump Sensitizes Cancer Cells to Anoikis and Prevents Distant Tumor Formation

Slit Receptor EVA-1 Coactivates a SAX-3/Robo-Mediated Guidance Signal in C. elegans

C4ST-1/CHST11-controlled chondroitin sulfation interferes with oncogenic HRAS signaling in Costello syndrome

Mechanism of activation of the TGF-β receptor

Structural Basis of Smad2 Recognition by the Smad Anchor for Receptor Activation

Next-generation RNA Sequencing of Archival Formalin-fixed Paraffin-embedded Urothelial Bladder Cancer

Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain

Signaling and Endocytosis: A Team Effort for Cell Migration

Genome-Wide Identification of Smad/Foxh1 Targets Reveals a Role for Foxh1 in Retinoic Acid Regulation and Forebrain Development

A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesis

The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development

Chemical enhancers of cytokine signaling that suppress microfilament turnover and tumor cell growth

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