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Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis

Diabetologia, 2005-11, Vol.48 (11), p.2313-2321

2005

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Conditional ablation of Gsk-3β in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice

Diabetologia, 2010-12, Vol.53 (12), p.2600-2610

2010

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Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR) a A meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians

Diabetologia, 1998-12, Vol.41 (12), p.1511-1515

1998

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Adenosine Diphosphate as an Intracellular Regulator of Insulin Secretion

Science (American Association for the Advancement of Science), 1996-06, Vol.272 (5269), p.1785-1787

1996

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A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)

Nature genetics, 1998-10, Vol.20 (2), p.143-148

1998

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Familial Hyperinsulinism Caused by an Activating Glucokinase Mutation

The New England journal of medicine, 1998-01, Vol.338 (4), p.226-230

1998

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Dysregulation of Insulin Secretion in Children With Congenital Hyperinsulinism due to Sulfonylurea Receptor Mutations

Diabetes (New York, N.Y.), 2001-02, Vol.50 (2), p.322-328

2001

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Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation

Diabetologia, 2008-09, Vol.51 (9), p.1646-1652

2008

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Functional analyses of novel mutations in the sulfonylurea receptor 1 associated with persistent hyperinsulinemic hypoglycemia of infancy

Diabetes (New York, N.Y.), 1998-07, Vol.47 (7), p.1145-1151

1998

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Mice with beta cell overexpression of glycogen synthase kinase-3β have reduced beta cell mass and proliferation

Diabetologia, 2008-04, Vol.51 (4), p.623-631

2008

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An expression profile of human pancreatic islet mRNAs by Serial Analysis of Gene expression (SAGE)

Diabetologia, 2004-02, Vol.47 (2), p.284-299

2004

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Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus

Nature (London), 1992-03, Vol.356 (6365), p.162-164

1992

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Genetic Heterogeneity in Familial Hyperinsulinism

Human molecular genetics, 1998-07, Vol.7 (7), p.1119-1128

1998

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Glucokinase as pancreatic β cell glucose sensor and diabetes gene

The Journal of clinical investigation, 1993-11, Vol.92 (5), p.2092-2098

1993

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Clinical Characteristics of Subjects with a Missense Mutation in Glucokinase

Diabetic medicine, 1995-03, Vol.12 (3), p.209-217

1995

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Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene

Diabetes (New York, N.Y.), 1998-04, Vol.47 (4), p.598-605

1998

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Glucose and other insulin secretagogues induce, rather than inhibit, expression of Id-1 and Id-3 in pancreatic islet beta cells

Diabetologia, 2001-04, Vol.44 (4), p.453-463

2001

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Linkage of type 2 diabetes to the glucokinase gene

The Lancet (British edition), 1992-05, Vol.339 (8805), p.1307-1310

1992

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A Genome Scan for Type 2 Diabetes Susceptibility Loci in a Genetically Isolated Population

Diabetes (New York, N.Y.), 2001-03, Vol.50 (3), p.681-685

2001

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Hyperinsulinism: molecular aetiology of focal disease

Archives of disease in childhood, 1998-11, Vol.79 (5), p.445-447

1998

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Familial hyperinsulinism with apparent autosomal dominant inheritance: Clinical and genetic differences from the autosomal recessive variant

The Journal of pediatrics, 1998, Vol.132 (1), p.9-14

1998

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A mutation in the Glut2 glucose transporter gene of a diabetic patient abolishes transport activity

The Journal of biological chemistry, 1994-07, Vol.269 (27), p.17765-17767

1994

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Searching for Type 2 Diabetes Genes in the Post-genome Era

Trends in Endocrinology & Metabolism, 2000-11, Vol.11 (9), p.383-393

2000

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The GENNID Study. A resource for mapping the genes that cause NIDDM

Diabetes care, 1996-08, Vol.19 (8), p.864-872

1996

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Identification and functional analysis of sulfonylurea receptor 1 variants in Japanese patients with NIDDM

Diabetes (New York, N.Y.), 1998-03, Vol.47 (3), p.476-481

1998

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Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis

Conditional ablation of Gsk-3β in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice

Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR) a A meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians

Adenosine Diphosphate as an Intracellular Regulator of Insulin Secretion

A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)

Familial Hyperinsulinism Caused by an Activating Glucokinase Mutation

Dysregulation of Insulin Secretion in Children With Congenital Hyperinsulinism due to Sulfonylurea Receptor Mutations

Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation

Functional analyses of novel mutations in the sulfonylurea receptor 1 associated with persistent hyperinsulinemic hypoglycemia of infancy

Mice with beta cell overexpression of glycogen synthase kinase-3β have reduced beta cell mass and proliferation

An expression profile of human pancreatic islet mRNAs by Serial Analysis of Gene expression (SAGE)

Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus

Genetic Heterogeneity in Familial Hyperinsulinism

Glucokinase as pancreatic β cell glucose sensor and diabetes gene

Clinical Characteristics of Subjects with a Missense Mutation in Glucokinase

Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene

Glucose and other insulin secretagogues induce, rather than inhibit, expression of Id-1 and Id-3 in pancreatic islet beta cells

Linkage of type 2 diabetes to the glucokinase gene

A Genome Scan for Type 2 Diabetes Susceptibility Loci in a Genetically Isolated Population

Hyperinsulinism: molecular aetiology of focal disease

Familial hyperinsulinism with apparent autosomal dominant inheritance: Clinical and genetic differences from the autosomal recessive variant

A mutation in the Glut2 glucose transporter gene of a diabetic patient abolishes transport activity

Searching for Type 2 Diabetes Genes in the Post-genome Era

The GENNID Study. A resource for mapping the genes that cause NIDDM

Identification and functional analysis of sulfonylurea receptor 1 variants in Japanese patients with NIDDM

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