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Guidelines for the welfare and use of animals in cancer research

British journal of cancer, 2010-05, Vol.102 (11), p.1555-1577

2010

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A novel small molecule hydroxamate preferentially inhibits HDAC6 activity and tumour growth

British journal of cancer, 2013-02, Vol.108 (2), p.342-350

2013

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Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death

Oncogene, 2009-11, Vol.28 (45), p.4009-4021

2009

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Malignant transformation alters membrane choline phospholipid metabolism of human mammary epithelial cells

Cancer research (Chicago, Ill.), 1999, Vol.59 (1), p.80-84

1999

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The future of imaging: developing the tools for monitoring response to therapy in oncology: the 2009 Sir James MacKenzie Davidson Memorial lecture

British journal of radiology, 2010-10, Vol.83 (994), p.814-822

ABOAGYE, E. O

2010

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Development of a cyclin-dependent kinase inhibitor devoid of ABC transporter-dependent drug resistance

British journal of cancer, 2013-10, Vol.109 (9), p.2356-2367

2013

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In vivo evaluation of [18F]fluoroetanidazole as a new marker for imaging tumour hypoxia with positron emission tomography

British journal of cancer, 2004-06, Vol.90 (11), p.2232-2242

2004

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An open-label study of lapatinib in women with HER-2-negative early breast cancer: the lapatinib pre-surgical study (LPS study)

Annals of oncology, 2013-04, Vol.24 (4), p.924-930

2013

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Plasma pharmacokinetics and metabolism of the histone deacetylase inhibitor trichostatin a after intraperitoneal administration to mice

Drug metabolism and disposition, 2004-10, Vol.32 (10), p.1132-1138

2004

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In vitro selectivity, in vivo biodistribution and tumour uptake of annexin V radiolabelled with a positron emitting radioisotope

British journal of cancer, 2003-10, Vol.89 (7), p.1327-1333

2003

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Adenovirus biodistribution and noninvasive imaging of gene expression in vivo by positron emission tomography using human sodium/iodide symporter as reporter gene

Human gene therapy, 2002-09, Vol.13 (14), p.1723-1735

2002

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In vivo pharmacokinetics and pharmacodynamics in drug development using positron-emission tomography

Drug Discovery Today, 2001-03, Vol.6 (6), p.293-302

2001

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Plasma pharmacokinetic evaluation of cytotoxic agents radiolabelled with positron emitting radioisotopes

Cancer chemotherapy and pharmacology, 2008-04, Vol.61 (5), p.865-873

2008

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Pharmacokinetic Evaluation of N-[2-(Dimethylamino)Ethyl]Acridine-4-Carboxamide in Patients by Positron Emission Tomography

Journal of clinical oncology, 2001-03, Vol.19 (5), p.1421-1429

2001

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Extraction of 5-Fluorouracil by tumor and liver: a noninvasive positron emission tomography study of patients with gastrointestinal cancer

Cancer research (Chicago, Ill.), 2001-07, Vol.61 (13), p.4937-4941

2001

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Intratumoral conversion of 5-fluorocytosine to 5-fluorouracil by monoclonal antibody-cytosine deaminase conjugates : Noninvasive detection of prodrug activation by magnetic resonance spectroscopy and spectroscopic imaging

Cancer research (Chicago, Ill.), 1998-09, Vol.58 (18), p.4075-4078

1998

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Cancer Research UK procedures in manufacture and toxicology of radiotracers intended for Pre-phase I positron emission tomography studies in cancer patients

British journal of cancer, 2002-04, Vol.86 (7), p.1052-1056

2002

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Carbogen breathing increases 5-fluorouracil uptake and cytotoxicity in hypoxic murine RIF-1 tumors : A magnetic resonance study in vivo

Cancer research (Chicago, Ill.), 1998-03, Vol.58 (6), p.1185-1194

1998

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Preclinical evaluation of the fluorinated 2-nitroimidazole N-(2-hydroxy-3,3,3-trifluoropropyl)-2-(2-nitro-1-imidazolyl) acetamide (SR-4554) as a probe for the measurement of tumor hypoxia

Cancer research (Chicago, Ill.), 1997-08, Vol.57 (15), p.3314-3318

1997

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Detection of tumor response to chemotherapy by 1H nuclear magnetic resonance spectroscopy : Effect of 5-fluorouracil on lactate levels in radiation-induced fibrosarcoma 1 tumors

Cancer research (Chicago, Ill.), 1998-03, Vol.58 (5), p.1063-1067

1998

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Bioreductive metabolism of the novel fluorinated 2-nitroimidazole hypoxia probe N-(2-hydroxy-3, 3,3-trifluoropropyl)-2-(2-nitroimidazolyl) acetamide (SR-4554)

Biochemical pharmacology, 1997-12, Vol.54 (11), p.1217-1224

1997

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Inhibiting estrogen responses in breast cancer cells using a fusion protein encoding estrogen receptor-α and the transcriptional repressor PLZF

Gene therapy, 2005-03, Vol.12 (5), p.452-460

2005

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Comparative biodistribution and metabolism of carbon-11-labeled N-[2-(dimethylamino)ethyl]acridine-4-carboxamide and DNA-intercalating analogues

Cancer research (Chicago, Ill.), 2001-04, Vol.61 (7), p.2935-2944

2001

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The relationship between tumour oxygenation determined by oxygen electrode measurements and magnetic resonance spectroscopy of the fluorinated 2-nitroimidazole SR-4554

British journal of cancer, 1998-01, Vol.77 (1), p.65-70

1998

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Early detection of tumor response to chemotherapy by 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography : The effect of cisplatin on a fibrosarcoma tumor model in vivo

Cancer research (Chicago, Ill.), 2005-05, Vol.65 (10), p.4202-4210

2005

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Guidelines for the welfare and use of animals in cancer research

A novel small molecule hydroxamate preferentially inhibits HDAC6 activity and tumour growth

Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death

Malignant transformation alters membrane choline phospholipid metabolism of human mammary epithelial cells

The future of imaging: developing the tools for monitoring response to therapy in oncology: the 2009 Sir James MacKenzie Davidson Memorial lecture

Development of a cyclin-dependent kinase inhibitor devoid of ABC transporter-dependent drug resistance

In vivo evaluation of [18F]fluoroetanidazole as a new marker for imaging tumour hypoxia with positron emission tomography

An open-label study of lapatinib in women with HER-2-negative early breast cancer: the lapatinib pre-surgical study (LPS study)

Plasma pharmacokinetics and metabolism of the histone deacetylase inhibitor trichostatin a after intraperitoneal administration to mice

In vitro selectivity, in vivo biodistribution and tumour uptake of annexin V radiolabelled with a positron emitting radioisotope

Adenovirus biodistribution and noninvasive imaging of gene expression in vivo by positron emission tomography using human sodium/iodide symporter as reporter gene

In vivo pharmacokinetics and pharmacodynamics in drug development using positron-emission tomography

Plasma pharmacokinetic evaluation of cytotoxic agents radiolabelled with positron emitting radioisotopes

Pharmacokinetic Evaluation of N-[2-(Dimethylamino)Ethyl]Acridine-4-Carboxamide in Patients by Positron Emission Tomography

Extraction of 5-Fluorouracil by tumor and liver: a noninvasive positron emission tomography study of patients with gastrointestinal cancer

Intratumoral conversion of 5-fluorocytosine to 5-fluorouracil by monoclonal antibody-cytosine deaminase conjugates : Noninvasive detection of prodrug activation by magnetic resonance spectroscopy and spectroscopic imaging

Cancer Research UK procedures in manufacture and toxicology of radiotracers intended for Pre-phase I positron emission tomography studies in cancer patients

Carbogen breathing increases 5-fluorouracil uptake and cytotoxicity in hypoxic murine RIF-1 tumors : A magnetic resonance study in vivo

Preclinical evaluation of the fluorinated 2-nitroimidazole N-(2-hydroxy-3,3,3-trifluoropropyl)-2-(2-nitro-1-imidazolyl) acetamide (SR-4554) as a probe for the measurement of tumor hypoxia

Detection of tumor response to chemotherapy by 1H nuclear magnetic resonance spectroscopy : Effect of 5-fluorouracil on lactate levels in radiation-induced fibrosarcoma 1 tumors

Bioreductive metabolism of the novel fluorinated 2-nitroimidazole hypoxia probe N-(2-hydroxy-3, 3,3-trifluoropropyl)-2-(2-nitroimidazolyl) acetamide (SR-4554)

Inhibiting estrogen responses in breast cancer cells using a fusion protein encoding estrogen receptor-α and the transcriptional repressor PLZF

Comparative biodistribution and metabolism of carbon-11-labeled N-[2-(dimethylamino)ethyl]acridine-4-carboxamide and DNA-intercalating analogues

The relationship between tumour oxygenation determined by oxygen electrode measurements and magnetic resonance spectroscopy of the fluorinated 2-nitroimidazole SR-4554

Early detection of tumor response to chemotherapy by 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography : The effect of cisplatin on a fibrosarcoma tumor model in vivo

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