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The anti-inflammatory activity of curcumin is mediated by its oxidative metabolites

The Journal of biological chemistry, 2017-12, Vol.292 (52), p.21243-21252

2017

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Routes to 4-Hydroxynonenal: Fundamental Issues in the Mechanisms of Lipid Peroxidation

The Journal of biological chemistry, 2008-06, Vol.283 (23), p.15539-15543

2008

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Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling

Oncogene, 2020-05, Vol.39 (22), p.4465-4474

2020

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Targeting Mammalian 5-Lipoxygenase by Dietary Phenolics as an Anti-Inflammatory Mechanism: A Systematic Review

International journal of molecular sciences, 2021-07, Vol.22 (15), p.7937

2021

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Autoxidative and Cyclooxygenase-2 Catalyzed Transformation of the Dietary Chemopreventive Agent Curcumin

The Journal of biological chemistry, 2011-01, Vol.286 (2), p.1114-1124

2011

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Oxidative Metabolites of Curcumin Poison Human Type II Topoisomerases

Biochemistry (Easton), 2013-01, Vol.52 (1), p.221-227

2013

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Curcumin activates G protein-coupled receptor 97 (GPR97) in a manner different from glucocorticoid

Biochemical and biophysical research communications, 2022-03, Vol.595, p.41-46

2022

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Formation of 4-hydroxynonenal from cardiolipin oxidation: Intramolecular peroxyl radical addition and decomposition

Free radical biology & medicine, 2011-01, Vol.50 (1), p.166-178

2011

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Kaempferol increases levels of coenzyme Q in kidney cells and serves as a biosynthetic ring precursor

Free radical biology & medicine, 2017-09, Vol.110, p.176-187

2017

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Curcumin induces secretion of glucagon-like peptide-1 through an oxidation-dependent mechanism

Biochimie, 2019-10, Vol.165, p.250-257

2019

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COX-2-dependent and -independent biosynthesis of dihydroxy-arachidonic acids in activated human leukocytes

Journal of lipid research, 2012-01, Vol.53 (1), p.87-94

2012

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The hepoxilin connection in the epidermis

The FEBS journal, 2007-07, Vol.274 (14), p.3494-3502

2007

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A 49-kDa Mini-lipoxygenase from Anabaena sp. PCC 7120 Retains Catalytically Complete Functionality

The Journal of biological chemistry, 2008-02, Vol.283 (8), p.5138-5147

2008

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Convergence of the 5-LOX and COX-2 pathways: heme-catalyzed cleavage of the 5S-HETE-derived di-endoperoxide into aldehyde fragments

Journal of lipid research, 2009-12, Vol.50 (12), p.2455-2462

2009

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Transformation of Prostaglandin D 2 to 11-Dehydro Thromboxane B 2 by Baeyer-Villiger Oxidation

Lipids, 2020-01, Vol.55 (1), p.73-78

2020

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Evidence for an Ionic Intermediate in the Transformation of Fatty Acid Hydroperoxide by a Catalase-related Allene Oxide Synthase from the Cyanobacterium Acaryochloris marina

The Journal of biological chemistry, 2009-08, Vol.284 (33), p.22087-22098

2009

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Facile synthesis of deuterated and [14C]labeled analogs of vanillin and curcumin for use as mechanistic and analytical tools

Journal of labelled compounds & radiopharmaceuticals, 2013-12, Vol.56 (14), p.696-699

2013

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On the Relationships of Substrate Orientation, Hydrogen Abstraction, and Product Stereochemistry in Single and Double Dioxygenations by Soybean Lipoxygenase-1 and Its Ala542Gly Mutant

The Journal of biological chemistry, 2005-11, Vol.280 (46), p.38756-38766

2005

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Unraveling curcumin degradation: autoxidation proceeds through spiroepoxide and vinylether intermediates en route to the main bicyclopentadione

The Journal of biological chemistry, 2015-02, Vol.290 (8), p.4817-4828

2015

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Vanillin and ferulic acid: not the major degradation products of curcumin

Trends in molecular medicine, 2012-07, Vol.18 (7), p.361-363

2012

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Biosynthesis of a linoleic acid allylic epoxide: mechanistic comparison with its chemical synthesis and leukotriene A biosynthesis[S]

Journal of lipid research, 2009-07, Vol.50 (7), p.1448-1455

2009

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Identification of Two Cyclooxygenase Active Site Residues, Leucine 384 and Glycine 526, That Control Carbon Ring Cyclization in Prostaglandin Biosynthesis

The Journal of biological chemistry, 2004-02, Vol.279 (6), p.4404-4414

2004

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Residual cyclooxygenase activity of aspirin‐acetylated COX‐2 forms 15R‐prostaglandins that inhibit platelet aggregation

The FASEB journal, 2019-01, Vol.33 (1), p.1033-1041

2019

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Amino Acid Determinants in Cyclooxygenase-2 Oxygenation of the Endocannabinoid 2-Arachidonylglycerol

The Journal of biological chemistry, 2001-08, Vol.276 (32), p.30072-30077

2001

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Curcumin, but not curcumin-glucuronide, inhibits Smad signaling in TGFβ-dependent bone metastatic breast cancer cells and is enriched in bone compared to other tissues

The Journal of nutritional biochemistry, 2019-01, Vol.63, p.150-156

2019

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The anti-inflammatory activity of curcumin is mediated by its oxidative metabolites

Routes to 4-Hydroxynonenal: Fundamental Issues in the Mechanisms of Lipid Peroxidation

Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling

Targeting Mammalian 5-Lipoxygenase by Dietary Phenolics as an Anti-Inflammatory Mechanism: A Systematic Review

Autoxidative and Cyclooxygenase-2 Catalyzed Transformation of the Dietary Chemopreventive Agent Curcumin

Oxidative Metabolites of Curcumin Poison Human Type II Topoisomerases

Curcumin activates G protein-coupled receptor 97 (GPR97) in a manner different from glucocorticoid

Formation of 4-hydroxynonenal from cardiolipin oxidation: Intramolecular peroxyl radical addition and decomposition

Kaempferol increases levels of coenzyme Q in kidney cells and serves as a biosynthetic ring precursor

Curcumin induces secretion of glucagon-like peptide-1 through an oxidation-dependent mechanism

COX-2-dependent and -independent biosynthesis of dihydroxy-arachidonic acids in activated human leukocytes

The hepoxilin connection in the epidermis

A 49-kDa Mini-lipoxygenase from Anabaena sp. PCC 7120 Retains Catalytically Complete Functionality

Convergence of the 5-LOX and COX-2 pathways: heme-catalyzed cleavage of the 5S-HETE-derived di-endoperoxide into aldehyde fragments

Transformation of Prostaglandin D 2 to 11-Dehydro Thromboxane B 2 by Baeyer-Villiger Oxidation

Evidence for an Ionic Intermediate in the Transformation of Fatty Acid Hydroperoxide by a Catalase-related Allene Oxide Synthase from the Cyanobacterium Acaryochloris marina

Facile synthesis of deuterated and [14C]labeled analogs of vanillin and curcumin for use as mechanistic and analytical tools

On the Relationships of Substrate Orientation, Hydrogen Abstraction, and Product Stereochemistry in Single and Double Dioxygenations by Soybean Lipoxygenase-1 and Its Ala542Gly Mutant

Unraveling curcumin degradation: autoxidation proceeds through spiroepoxide and vinylether intermediates en route to the main bicyclopentadione

Vanillin and ferulic acid: not the major degradation products of curcumin

Biosynthesis of a linoleic acid allylic epoxide: mechanistic comparison with its chemical synthesis and leukotriene A biosynthesis[S]

Identification of Two Cyclooxygenase Active Site Residues, Leucine 384 and Glycine 526, That Control Carbon Ring Cyclization in Prostaglandin Biosynthesis

Residual cyclooxygenase activity of aspirin‐acetylated COX‐2 forms 15R‐prostaglandins that inhibit platelet aggregation

Amino Acid Determinants in Cyclooxygenase-2 Oxygenation of the Endocannabinoid 2-Arachidonylglycerol

Curcumin, but not curcumin-glucuronide, inhibits Smad signaling in TGFβ-dependent bone metastatic breast cancer cells and is enriched in bone compared to other tissues

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