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An Improved Ivermectin-activated Chloride Channel Receptor for Inhibiting Electrical Activity in Defined Neuronal Populations

The Journal of biological chemistry, 2010-05, Vol.285 (20), p.14890-14897

2010

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An outline of desensitization in pentameric ligand-gated ion channel receptors

Cellular and molecular life sciences : CMLS, 2013-04, Vol.70 (7), p.1241-1253

2013

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Correlating Structural and Energetic Changes in Glycine Receptor Activation

The Journal of biological chemistry, 2015-02, Vol.290 (9), p.5621-5634

2015

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Investigating the Mechanism by Which Gain-of-function Mutations to the α1 Glycine Receptor Cause Hyperekplexia

The Journal of biological chemistry, 2016-07, Vol.291 (29), p.15332-15341

2016

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Stoichiometry and Subunit Arrangement of α1β Glycine Receptors As Determined by Atomic Force Microscopy

Biochemistry (Easton), 2012-07, Vol.51 (26), p.5229-5231

2012

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The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer’s Disease Drug Memantine

Structure (London), 2014-10, Vol.22 (10), p.1399-1407

2014

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Pharmacological activation of ATF6 remodels the proteostasis network to rescue pathogenic GABAA receptors

Cell & bioscience, 2022-04, Vol.12 (1), p.1-48, Article 48

2022

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Probing the Structural Mechanism of Partial Agonism in Glycine Receptors Using the Fluorescent Artificial Amino Acid, ANAP

ACS chemical biology, 2017-03, Vol.12 (3), p.805-813

2017

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Australian marine sponge alkaloids as a new class of glycine-gated chloride channel receptor modulator

Bioorganic & medicinal chemistry, 2013-07, Vol.21 (14), p.4420-4425

2013

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Phosphorylation of α3 Glycine Receptors Induces a Conformational Change in the Glycine-Binding Site

ACS chemical neuroscience, 2013-10, Vol.4 (10), p.1361-1370

2013

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Conformational Variability of the Glycine Receptor M2 Domain in Response to Activation by Different Agonists

The Journal of biological chemistry, 2007-12, Vol.282 (49), p.36057-36067

2007

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GLRB is the third major gene of effect in hyperekplexia

Human molecular genetics, 2013-03, Vol.22 (5), p.927-940

2013

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GABAA Receptor α and γ Subunits Shape Synaptic Currents via Different Mechanisms

The Journal of biological chemistry, 2014-02, Vol.289 (9), p.5399-5411

2014

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Ircinialactams: Subunit-selective glycine receptor modulators from Australian sponges of the family Irciniidae

Bioorganic & medicinal chemistry, 2010-04, Vol.18 (8), p.2912-2919

2010

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proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore

Journal of neurochemistry, 2007-10, Vol.103 (2), p.580-589

2007

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Phosphorylation mediated structural and functional changes in pentameric ligand-gated ion channels: Implications for drug discovery

The international journal of biochemistry & cell biology, 2014-08, Vol.53, p.218-223

2014

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Analysis of Hyperekplexia Mutations Identifies Transmembrane Domain Rearrangements That Mediate Glycine Receptor Activation

The Journal of biological chemistry, 2013-11, Vol.288 (47), p.33760-33771

2013

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Structure-activity analysis of ginkgolide binding in the glycine receptor pore

Journal of neurochemistry, 2008-05, Vol.105 (4), p.1418-1427

2008

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Activation and Desensitization Induce Distinct Conformational Changes at the Extracellular-Transmembrane Domain Interface of the Glycine Receptor

The Journal of biological chemistry, 2011-11, Vol.286 (44), p.38814-38824

2011

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Proteostasis Regulators Restore Function of Epilepsy-Associated GABAA Receptors

Cell chemical biology, 2021-01, Vol.28 (1), p.46-59.e7

2021

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Molecular determinants of ginkgolide binding in the glycine receptor pore

Journal of neurochemistry, 2006-07, Vol.98 (2), p.395-407

2006

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A comparison of glycine- and ivermectin-mediated conformational changes in the glycine receptor ligand-binding domain

The international journal of biochemistry & cell biology, 2012-02, Vol.44 (2), p.335-340

2012

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Distinct properties of glycine receptor β+/α- interface: unambiguously characterizing heteromeric interface reconstituted in homomeric protein

The Journal of biological chemistry, 2012-06, Vol.287 (25), p.21244-21252

2012

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Molecular Determinants of Ivermectin Sensitivity at the Glycine Receptor Chloride Channel

The Journal of biological chemistry, 2011-12, Vol.286 (51), p.43913-43924

2011

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Insights into the Structural Basis for Zinc Inhibition of the Glycine Receptor

The Journal of biological chemistry, 2003-08, Vol.278 (31), p.28985-28992

2003

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An Improved Ivermectin-activated Chloride Channel Receptor for Inhibiting Electrical Activity in Defined Neuronal Populations

An outline of desensitization in pentameric ligand-gated ion channel receptors

Correlating Structural and Energetic Changes in Glycine Receptor Activation

Investigating the Mechanism by Which Gain-of-function Mutations to the α1 Glycine Receptor Cause Hyperekplexia

Stoichiometry and Subunit Arrangement of α1β Glycine Receptors As Determined by Atomic Force Microscopy

The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer’s Disease Drug Memantine

Pharmacological activation of ATF6 remodels the proteostasis network to rescue pathogenic GABAA receptors

Probing the Structural Mechanism of Partial Agonism in Glycine Receptors Using the Fluorescent Artificial Amino Acid, ANAP

Australian marine sponge alkaloids as a new class of glycine-gated chloride channel receptor modulator

Phosphorylation of α3 Glycine Receptors Induces a Conformational Change in the Glycine-Binding Site

Conformational Variability of the Glycine Receptor M2 Domain in Response to Activation by Different Agonists

GLRB is the third major gene of effect in hyperekplexia

GABAA Receptor α and γ Subunits Shape Synaptic Currents via Different Mechanisms

Ircinialactams: Subunit-selective glycine receptor modulators from Australian sponges of the family Irciniidae

proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore

Phosphorylation mediated structural and functional changes in pentameric ligand-gated ion channels: Implications for drug discovery

Analysis of Hyperekplexia Mutations Identifies Transmembrane Domain Rearrangements That Mediate Glycine Receptor Activation

Structure-activity analysis of ginkgolide binding in the glycine receptor pore

Activation and Desensitization Induce Distinct Conformational Changes at the Extracellular-Transmembrane Domain Interface of the Glycine Receptor

Proteostasis Regulators Restore Function of Epilepsy-Associated GABAA Receptors

Molecular determinants of ginkgolide binding in the glycine receptor pore

A comparison of glycine- and ivermectin-mediated conformational changes in the glycine receptor ligand-binding domain

Distinct properties of glycine receptor β+/α- interface: unambiguously characterizing heteromeric interface reconstituted in homomeric protein

Molecular Determinants of Ivermectin Sensitivity at the Glycine Receptor Chloride Channel

Insights into the Structural Basis for Zinc Inhibition of the Glycine Receptor

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