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Mechanisms of Cotranslational Maturation of Newly Synthesized Proteins

Annual review of biochemistry, 2019-06, Vol.88 (1), p.337-364

2019

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The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteins

Nature structural & molecular biology, 2009-06, Vol.16 (6), p.589-597

2009

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Selective 40S Footprinting Reveals Cap-Tethered Ribosome Scanning in Human Cells

Molecular cell, 2020-08, Vol.79 (4), p.561-574.e5

2020

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Structure and function of the molecular chaperone Trigger Factor

Biochimica et biophysica acta, 2010-06, Vol.1803 (6), p.650-661

2010

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Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production

Cell, 2020-05, Vol.181 (4), p.818-831.e19

2020

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Co-translational mechanisms of protein maturation

Current opinion in structural biology, 2014-02, Vol.24, p.24-33

2014

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A chemical kinetic basis for measuring translation initiation and elongation rates from ribosome profiling data

PLoS computational biology, 2019-05, Vol.15 (5), p.e1007070-e1007070

2019

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Selective Ribosome Profiling Reveals the Cotranslational Chaperone Action of Trigger Factor In Vivo

Cell, 2011-12, Vol.147 (6), p.1295-1308

2011

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Trigger Factor Reduces the Force Exerted on the Nascent Chain by a Cotranslationally Folding Protein

Journal of molecular biology, 2016-03, Vol.428 (6), p.1356-1364

2016

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Selective ribosome profiling to study interactions of translating ribosomes in yeast

Nature protocols, 2019-08, Vol.14 (8), p.2279-2317

2019

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Selective ribosome profiling as a tool for studying the interaction of chaperones and targeting factors with nascent polypeptide chains and ribosomes

Nature protocols, 2013-11, Vol.8 (11), p.2212-2239

2013

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SecA2 Associates with Translating Ribosomes and Contributes to the Secretion of Potent IFN-β Inducing RNAs

International journal of molecular sciences, 2022-11, Vol.23 (23), p.15021

2022

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Concerted Action of the Ribosome and the Associated Chaperone Trigger Factor Confines Nascent Polypeptide Folding

Molecular cell, 2012-10, Vol.48 (1), p.63-74

2012

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Spatially and kinetically resolved changes in the conformational dynamics of the Hsp90 chaperone machine

The EMBO journal, 2009-03, Vol.28 (5), p.602-613

2009

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Mechanisms of Cotranslational Protein Maturation in Bacteria

Frontiers in molecular biosciences, 2021-05, Vol.8, p.689755-689755

2021

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Dynamic enzyme docking to the ribosome coordinates N-terminal processing with polypeptide folding

Nature structural & molecular biology, 2013-07, Vol.20 (7), p.843-850

2013

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Large-scale purification of ribosome-nascent chain complexes for biochemical and structural studies

FEBS letters, 2009-07, Vol.583 (14), p.2407-2413

2009

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Trigger Factor and DnaK possess overlapping substrate pools and binding specificities

Molecular microbiology, 2003-03, Vol.47 (5), p.1317-1328

2003

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Dimerization of the Human E3 Ligase CHIP via a Coiled-coil Domain Is Essential for Its Activity

The Journal of biological chemistry, 2004-01, Vol.279 (4), p.2673-2678

2004

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Profiling Ssb-Nascent Chain Interactions Reveals Principles of Hsp70-Assisted Folding

Cell, 2017-07, Vol.170 (2), p.298-311.e20

2017

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Pairs of amino acids at the P- and A-sites of the ribosome predictably and causally modulate translation-elongation rates

Journal of molecular biology, 2020-12, Vol.432 (24), p.166696-166696, Article 166696

2020

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SecA Interacts with Ribosomes in Order to Facilitate Posttranslational Translocation in Bacteria

Molecular cell, 2011-02, Vol.41 (3), p.343-353

2011

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Systemic control of protein synthesis through sequestration of translation and ribosome biogenesis factors during severe heat stress

FEBS letters, 2015-11, Vol.589 (23), p.3654-3664

2015

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Protein Folding Mediated by Trigger Factor and Hsp70: New Insights from Single-Molecule Approaches

Journal of molecular biology, 2018-02, Vol.430 (4), p.438-449

2018

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Mechanisms of Cotranslational Maturation of Newly Synthesized Proteins

The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteins

Selective 40S Footprinting Reveals Cap-Tethered Ribosome Scanning in Human Cells

Structure and function of the molecular chaperone Trigger Factor

Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production

Co-translational mechanisms of protein maturation

A chemical kinetic basis for measuring translation initiation and elongation rates from ribosome profiling data

Selective Ribosome Profiling Reveals the Cotranslational Chaperone Action of Trigger Factor In Vivo

Trigger Factor Reduces the Force Exerted on the Nascent Chain by a Cotranslationally Folding Protein

Selective ribosome profiling to study interactions of translating ribosomes in yeast

Selective ribosome profiling as a tool for studying the interaction of chaperones and targeting factors with nascent polypeptide chains and ribosomes

SecA2 Associates with Translating Ribosomes and Contributes to the Secretion of Potent IFN-β Inducing RNAs

Concerted Action of the Ribosome and the Associated Chaperone Trigger Factor Confines Nascent Polypeptide Folding

Spatially and kinetically resolved changes in the conformational dynamics of the Hsp90 chaperone machine

Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit

Mechanisms of Cotranslational Protein Maturation in Bacteria

Dynamic enzyme docking to the ribosome coordinates N-terminal processing with polypeptide folding

Large-scale purification of ribosome-nascent chain complexes for biochemical and structural studies

Trigger Factor and DnaK possess overlapping substrate pools and binding specificities

Dimerization of the Human E3 Ligase CHIP via a Coiled-coil Domain Is Essential for Its Activity

Profiling Ssb-Nascent Chain Interactions Reveals Principles of Hsp70-Assisted Folding

Pairs of amino acids at the P- and A-sites of the ribosome predictably and causally modulate translation-elongation rates

SecA Interacts with Ribosomes in Order to Facilitate Posttranslational Translocation in Bacteria

Systemic control of protein synthesis through sequestration of translation and ribosome biogenesis factors during severe heat stress

Protein Folding Mediated by Trigger Factor and Hsp70: New Insights from Single-Molecule Approaches

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