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Testing Implications of the Omnigenic Model for the Genetic Analysis of Loci Identified through Genome-wide Association

Current biology, 2021-03, Vol.31 (5), p.1092-1098.e6

2021

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The type III secretion injectisome, a complex nanomachine for intracellular ‘toxin’ delivery

Biological chemistry, 2010-07, Vol.391 (7), p.745-751

Cornelis, Guy R

2010

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The assembly of the export apparatus (YscR,S,T,U,V) of the Yersinia type III secretion apparatus occurs independently of other structural components and involves the formation of an YscV oligomer

Molecular microbiology, 2011-10, Vol.82 (2), p.502-514

2011

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Natural copy number variation of tandemly repeated regulatory SNORD RNAs leads to individual phenotypic differences in mice

Molecular ecology, 2021-10, Vol.30 (19), p.4708-4722

2021

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Recent Y chromosome divergence despite ancient origin of dioecy in poplars (Populus)

Molecular ecology, 2015-07, Vol.24 (13), p.3243-3256

2015

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Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase

Nature chemical biology, 2017-08, Vol.13 (8), p.850-857

2017

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Pat1 Contains Distinct Functional Domains That Promote P-Body Assembly and Activation of Decapping

Molecular and Cellular Biology, 2008-02, Vol.28 (4), p.1298-1312

2008

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Gut/Oral Bacteria Variability May Explain the High Efficacy of Green Tea in Rodent Tumor Inhibition and Its Absence in Humans

Molecules (Basel, Switzerland), 2020-10, Vol.25 (20), p.4753

2020

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Deciphering the assembly of the Yersinia type III secretion injectisome

The EMBO journal, 2010-06, Vol.29 (11), p.1928-1940

2010

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Scaffold composition and biological relevance of screening libraries

Nature chemical biology, 2007-08, Vol.3 (8), p.442-446

2007

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Monitoring Ligand-Induced Protein Ordering in Drug Discovery

Journal of molecular biology, 2016-03, Vol.428 (6), p.1290-1303

2016

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Evaluation of 1,1-cyclopropylidene as a thioether isostere in the 4-thio-thienopyrimidine (TTP) series of antimalarials

Bioorganic & medicinal chemistry, 2020-11, Vol.28 (22), p.115758-115758, Article 115758

2020

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Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors

Bioorganic & medicinal chemistry, 2018-01, Vol.26 (1), p.25-36

2018

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High-throughput assays for promiscuous inhibitors

Nature chemical biology, 2005-08, Vol.1 (3), p.146-148

2005

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Cysteine modifiers suggest an allosteric inhibitory site on the CAL PDZ domain

Bioscience reports, 2018-08, Vol.38 (4)

2018

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Evaluation of histone deacetylase inhibitors (HDACi) as therapeutic leads for human African trypanosomiasis (HAT)

Bioorganic & medicinal chemistry, 2015-08, Vol.23 (16), p.5151-5155

2015

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Identification of Toll-like receptor signaling inhibitors based on selective activation of hierarchically acting signaling proteins

Science signaling, 2018-08, Vol.11 (543)

2018

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Assembly of the Yersinia injectisome: the missing pieces

Molecular microbiology, 2012-09, Vol.85 (5), p.878-892

2012

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Identification and Characterization of the First Small Molecule Inhibitor of MDMX

The Journal of biological chemistry, 2010-04, Vol.285 (14), p.10786-10796

2010

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Inhibition of a viral enzyme by a small-molecule dimer disruptor

Nature chemical biology, 2009-09, Vol.5 (9), p.640-646

2009

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The 2010 Nucleic Acids Research Database Issue and online Database Collection: a community of data resources

Nucleic acids research, 2010-01, Vol.38 (Database issue), p.D1-D4

2010

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Structure of the Dodecameric Yersinia enterocolitica Secretin YscC and Its Trypsin-Resistant Core

Structure (London), 2013-12, Vol.21 (12), p.2152-2161

2013

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Yersinia enterocolitica type III secretion injectisomes form regularly spaced clusters, which incorporate new machines upon activation

Molecular microbiology, 2015-03, Vol.95 (5), p.875-884

2015

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NMR-based Structural Analysis of the Complete Rough-type Lipopolysaccharide Isolated from Capnocytophaga canimorsus

The Journal of biological chemistry, 2014-08, Vol.289 (34), p.23963-23976

2014

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Molecular mechanisms of heparin-induced modulation of human interleukin 12 bioactivity

The Journal of biological chemistry, 2019-03, Vol.294 (12), p.4412-4424

2019

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Testing Implications of the Omnigenic Model for the Genetic Analysis of Loci Identified through Genome-wide Association

The type III secretion injectisome, a complex nanomachine for intracellular ‘toxin’ delivery

The assembly of the export apparatus (YscR,S,T,U,V) of the Yersinia type III secretion apparatus occurs independently of other structural components and involves the formation of an YscV oligomer

Natural copy number variation of tandemly repeated regulatory SNORD RNAs leads to individual phenotypic differences in mice

Recent Y chromosome divergence despite ancient origin of dioecy in poplars (Populus)

Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase

Pat1 Contains Distinct Functional Domains That Promote P-Body Assembly and Activation of Decapping

Gut/Oral Bacteria Variability May Explain the High Efficacy of Green Tea in Rodent Tumor Inhibition and Its Absence in Humans

Deciphering the assembly of the Yersinia type III secretion injectisome

Scaffold composition and biological relevance of screening libraries

Monitoring Ligand-Induced Protein Ordering in Drug Discovery

Evaluation of 1,1-cyclopropylidene as a thioether isostere in the 4-thio-thienopyrimidine (TTP) series of antimalarials

Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors

High-throughput assays for promiscuous inhibitors

Cysteine modifiers suggest an allosteric inhibitory site on the CAL PDZ domain

Evaluation of histone deacetylase inhibitors (HDACi) as therapeutic leads for human African trypanosomiasis (HAT)

Identification of Toll-like receptor signaling inhibitors based on selective activation of hierarchically acting signaling proteins

Assembly of the Yersinia injectisome: the missing pieces

Identification and Characterization of the First Small Molecule Inhibitor of MDMX

Inhibition of a viral enzyme by a small-molecule dimer disruptor

The 2010 Nucleic Acids Research Database Issue and online Database Collection: a community of data resources

Structure of the Dodecameric Yersinia enterocolitica Secretin YscC and Its Trypsin-Resistant Core

Yersinia enterocolitica type III secretion injectisomes form regularly spaced clusters, which incorporate new machines upon activation

NMR-based Structural Analysis of the Complete Rough-type Lipopolysaccharide Isolated from Capnocytophaga canimorsus

Molecular mechanisms of heparin-induced modulation of human interleukin 12 bioactivity

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