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Pharmacological validation of TDO as a target for Parkinson’s disease

The FEBS journal, 2021-07, Vol.288 (14), p.4311-4331

2021

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A theoretical entropy score as a single value to express inhibitor selectivity

BMC bioinformatics, 2011-04, Vol.12 (1), p.94-94, Article 94

2011

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High-throughput fluorescence-based screening assays for tryptophan-catabolizing enzymes

Journal of biomolecular screening, 2014-10, Vol.19 (9), p.1266-1274

2014

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Ligand-induced folding of the guanine-sensing riboswitch is controlled by a combined predetermined induced fit mechanism

RNA (Cambridge), 2007-12, Vol.13 (12), p.2202-2212

2007

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Compound Selectivity and Target Residence Time of Kinase Inhibitors Studied with Surface Plasmon Resonance

Journal of molecular biology, 2017-02, Vol.429 (4), p.574-586

2017

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Target Residence Time-Guided Optimization on TTK Kinase Results in Inhibitors with Potent Anti-Proliferative Activity

Journal of molecular biology, 2017-07, Vol.429 (14), p.2211-2230

2017

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Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158

Journal of structural biology. X, 2020-01, Vol.4, p.100014-100014, Article 100014

2020

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A model for signaling specificity of Wnt/Frizzled combinations through co-receptor recruitment

FEBS letters, 2010-09, Vol.584 (18), p.3850-3854

2010

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Pharmacological Characterization of Receptor Redistribution and β-Arrestin Recruitment Assays for the Cannabinoid Receptor 1

Journal of biomolecular screening, 2009-08, Vol.14 (7), p.811-823

2009

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Characterization and optimization of a red-shifted fluorescence polarization ADP detection assay

Assay and drug development technologies, 2009-02, Vol.7 (1), p.56-67

2009

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β-Arrestin Recruitment and G Protein Signaling by the Atypical Human Chemokine Decoy Receptor CCX-CKR

The Journal of biological chemistry, 2013-03, Vol.288 (10), p.7169-7181

2013

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High-Throughput Fluorescence-Based Activity Assay for Arginase-1

SLAS discovery, 2020-10, Vol.25 (9), p.1018-1025

2020

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β-Galactosidase enzyme fragment complementation for the measurement of Wnt/β-catenin signaling

The FASEB journal, 2010-04, Vol.24 (4), p.1205-1217

2010

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β-Arrestin Recruitment Assay for the Identification of Agonists of the Sphingosine 1-Phosphate Receptor EDG1

Journal of biomolecular screening, 2008-12, Vol.13 (10), p.986-998

2008

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Controversies in ASSAY and drug development technologies: a focus on assessing irreproducibility

Assay and drug development technologies, 2014-10, Vol.12 (8), p.443-451

2014

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Cell-based screening

Combinatorial chemistry & high throughput screening, 2008-08, Vol.11 (7), p.494

Zaman, Guido J R

2008

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Membrane Topology and Glycosylation of the Human Multidrug Resistance-associated Protein (∗)

The Journal of biological chemistry, 1996-05, Vol.271 (21), p.12322-12326

1996

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High-throughput screening using beta-lactamase reporter-gene technology for identification of low-molecular-weight antagonists of the human gonadotropin releasing hormone receptor

Assay and drug development technologies, 2005-04, Vol.3 (2), p.143-154

2005

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Enzyme Fragment Complementation Binding Assay for p38 α Mitogen-Activated Protein Kinase to Study the Binding Kinetics of Enzyme Inhibitors

Assay and drug development technologies, 2006-08, Vol.4 (4), p.411-420

2006

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High-throughput screening with immobilized metal ion affinity-based fluorescence polarization detection, a homogeneous assay for protein kinases

Assay and drug development technologies, 2003-06, Vol.1 (3), p.445-453

2003

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A new experimental layout for non-aqueous enzymatic syntheses

Journal of molecular catalysis. B, Enzymatic, 2001-01, Vol.11 (4-6), p.961-965

2001

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Molecular Mechanisms of Wnt Pathway Specificity

Wnt Signaling in Development and Disease, 2014, p.101-112

2014

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The Effect of Water Content on the Thermostability of Solid-State Proteins

Annals of the New York Academy of Sciences, 1996-10, Vol.799 (1), p.108-114

1996

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Selection and characterization of randomly produced mutants of gene V protein of bacteriophage M13

European journal of biochemistry, 1992-03, Vol.204 (3), p.1003-1014

1992

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Translational regulation of M13 gene II protein by its cognate single‐stranded DNA binding protein

European journal of biochemistry, 1990-04, Vol.189 (1), p.119-124

1990

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Pharmacological validation of TDO as a target for Parkinson’s disease

A theoretical entropy score as a single value to express inhibitor selectivity

High-throughput fluorescence-based screening assays for tryptophan-catabolizing enzymes

Ligand-induced folding of the guanine-sensing riboswitch is controlled by a combined predetermined induced fit mechanism

Compound Selectivity and Target Residence Time of Kinase Inhibitors Studied with Surface Plasmon Resonance

Target Residence Time-Guided Optimization on TTK Kinase Results in Inhibitors with Potent Anti-Proliferative Activity

Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158

A model for signaling specificity of Wnt/Frizzled combinations through co-receptor recruitment

Pharmacological Characterization of Receptor Redistribution and β-Arrestin Recruitment Assays for the Cannabinoid Receptor 1

Characterization and optimization of a red-shifted fluorescence polarization ADP detection assay

β-Arrestin Recruitment and G Protein Signaling by the Atypical Human Chemokine Decoy Receptor CCX-CKR

High-Throughput Fluorescence-Based Activity Assay for Arginase-1

β-Galactosidase enzyme fragment complementation for the measurement of Wnt/β-catenin signaling

β-Arrestin Recruitment Assay for the Identification of Agonists of the Sphingosine 1-Phosphate Receptor EDG1

Controversies in ASSAY and drug development technologies: a focus on assessing irreproducibility

Cell-based screening

Membrane Topology and Glycosylation of the Human Multidrug Resistance-associated Protein (∗)

High-throughput screening using beta-lactamase reporter-gene technology for identification of low-molecular-weight antagonists of the human gonadotropin releasing hormone receptor

Enzyme Fragment Complementation Binding Assay for p38 α Mitogen-Activated Protein Kinase to Study the Binding Kinetics of Enzyme Inhibitors

High-throughput screening with immobilized metal ion affinity-based fluorescence polarization detection, a homogeneous assay for protein kinases

A new experimental layout for non-aqueous enzymatic syntheses

Molecular Mechanisms of Wnt Pathway Specificity

The Effect of Water Content on the Thermostability of Solid-State Proteins

Selection and characterization of randomly produced mutants of gene V protein of bacteriophage M13

Translational regulation of M13 gene II protein by its cognate single‐stranded DNA binding protein

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