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Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein

Nature communications, 2022-08, Vol.13 (1), p.4515-4515, Article 4515

2022

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Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins

Immunity (Cambridge, Mass.), 2021-04, Vol.54 (4), p.781-796.e4

2021

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The Impact of Sustained Immunization Regimens on the Antibody Response to Oligomannose Glycans

ACS chemical biology, 2020-03, Vol.15 (3), p.789-798

2020

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Structural Insights into the Lipid A Transport Pathway in MsbA

Structure (London), 2019-07, Vol.27 (7), p.1114-1123.e3

2019

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Structural basis for cooperative regulation of KIX-mediated transcription pathways by the HTLV-1 HBZ activation domain

Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (40), p.10040-10045

2018

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Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer

Nature communications, 2018-05, Vol.9 (1), p.1956-14, Article 1956

2018

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Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers

Scientific reports, 2017-08, Vol.7 (1), p.8390-15, Article 8390

2017

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Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike

Nature (London), 2017-07, Vol.547 (7663), p.360-363

2017

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Role of the CBP catalytic core in intramolecular SUMOylation and control of histone H3 acetylation

Proceedings of the National Academy of Sciences - PNAS, 2017-07, Vol.114 (27), p.E5335-E5342

2017

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Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein

Immunity (Cambridge, Mass.), 2017-05, Vol.46 (5), p.792-803.e3

2017

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HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

Immunity (Cambridge, Mass.), 2016-09, Vol.45 (3), p.483-496

2016

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Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose

Glycobiology (Oxford), 2015-04, Vol.25 (4), p.412-419

2015

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Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus

Nature communications, 2014-04, Vol.5 (1), p.3614-3614, Article 3614

2014

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Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (7), p.E738-E747

2014

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Hepatitis C Virus E2 Envelope Glycoprotein Core Structure

Science (American Association for the Advancement of Science), 2013-11, Vol.342 (6162), p.1090-1094

2013

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Malachite Green Mediates Homodimerization of Antibody VL Domains to Form a Fluorescent Ternary Complex with Singular Symmetric Interfaces

Journal of molecular biology, 2013-11, Vol.425 (22), p.4595-4613

2013

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Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans

PLoS pathogens, 2013-05, Vol.9 (5), p.e1003342

2013

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Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (38), p.15229-15234

2012

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A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

Science (American Association for the Advancement of Science), 2011-11, Vol.334 (6059), p.1097-1103

2011

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Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (25), p.11483-11488

2010

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Structure of the GLD-1 Homodimerization Domain: Insights into STAR Protein-Mediated Translational Regulation

Structure (London), 2010-03, Vol.18 (3), p.377-389

2010

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Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4

Science (American Association for the Advancement of Science), 2007-09, Vol.317 (5846), p.1930-1934

2007

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Structure of a V3-Containing HIV-1 gp120 Core

Science (American Association for the Advancement of Science), 2005-11, Vol.310 (5750), p.1025-1028

2005

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Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein

Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins

The Impact of Sustained Immunization Regimens on the Antibody Response to Oligomannose Glycans

Structural Insights into the Lipid A Transport Pathway in MsbA

Structural basis for cooperative regulation of KIX-mediated transcription pathways by the HTLV-1 HBZ activation domain

Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer

Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo

Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers

Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike

Role of the CBP catalytic core in intramolecular SUMOylation and control of histone H3 acetylation

Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose

Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus

Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign

Hepatitis C Virus E2 Envelope Glycoprotein Core Structure

Malachite Green Mediates Homodimerization of Antibody VL Domains to Form a Fluorescent Ternary Complex with Singular Symmetric Interfaces

Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans: e1003342

Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans

Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1

Structure of the GLD-1 Homodimerization Domain: Insights into STAR Protein-Mediated Translational Regulation

Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4

Structure of a V3-Containing HIV-1 gp120 Core

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