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Early Clinical Development of ARQ 197, a Selective, Non–ATP‐Competitive Inhibitor Targeting MET Tyrosine Kinase for the Treatment of Advanced Cancers

The oncologist (Dayton, Ohio), 2011-06, Vol.16 (6), p.788-799

2011

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Pemetrexed (ALIMTA), A Novel Multitargeted Antineoplastic Agent

Clinical cancer research, 2004-06, Vol.10 (12), p.4276s-4280s

ADJEI, Alex A

2004

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Advances in Chemotherapy of Non-small Cell Lung Cancer

Chest, 2006-10, Vol.130 (4), p.1211-1219

2006

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Phase II Trial of Pemetrexed Plus Bevacizumab for Second-Line Therapy of Patients With Advanced Non–Small-Cell Lung Cancer: NCCTG and SWOG Study N0426

Journal of clinical oncology, 2010-02, Vol.28 (4), p.614-619

2010

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Crosstalk between hedgehog and other signaling pathways as a basis for combination therapies in cancer

Cancer treatment reviews, 2014-07, Vol.40 (6), p.750-759

2014

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Phase I Trial of Sorafenib in Combination with Gefitinib in Patients with Refractory or Recurrent Non–Small Cell Lung Cancer

Clinical cancer research, 2007-05, Vol.13 (9), p.2684-2691

2007

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Correlation Between Polymorphisms of the Reduced Folate Carrier Gene (SLC19A1) and Survival After Pemetrexed-Based Therapy in Non-small Cell Lung Cancer: A North Central Cancer Treatment Group-Based Exploratory Study

Journal of thoracic oncology, 2010-09, Vol.5 (9), p.1346-1353

2010

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Evaluation of Lapatinib and Topotecan Combination Therapy: Tissue Culture, Murine Xenograft, and Phase I Clinical Trial Data

Clinical cancer research, 2008-12, Vol.14 (23), p.7900-7908

2008

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Results of combined‐modality therapy for limited‐stage small cell lung carcinoma in the elderly

Cancer, 2005-06, Vol.103 (11), p.2349-2354

2005

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A Randomized Double-Blind Phase II Study of the Seneca Valley Virus (NTX-010) versus Placebo for Patients with Extensive-Stage SCLC (ES SCLC) Who Were Stable or Responding after at Least Four Cycles of Platinum-Based Chemotherapy: North Central Cancer Treatment Group (Alliance) N0923 Study

Journal of thoracic oncology, 2020-01, Vol.15 (1), p.110-119

2020

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Randomized Phase II Trial of Three Schedules of Pemetrexed and Gemcitabine As Front-Line Therapy for Advanced Non–Small-Cell Lung Cancer

Journal of clinical oncology, 2005-09, Vol.23 (25), p.5929-5937

2005

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Lung cancer. How much platinum-based chemotherapy is enough in NSCLC?

Nature reviews. Clinical oncology, 2015-01, Vol.12 (1), p.8-10

2015

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A phase IB dose-escalation study of the safety and pharmacokinetics of pictilisib in combination with either paclitaxel and carboplatin (with or without bevacizumab) or pemetrexed and cisplatin (with or without bevacizumab) in patients with advanced non–small cell lung cancer

European journal of cancer (1990), 2017-11, Vol.86, p.186-196

2017

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Phase 1 Trial of Flavopiridol Combined with Cisplatin or Carboplatin in Patients with Advanced Malignancies with the Assessment of Pharmacokinetic and Pharmacodynamic End Points

Clinical cancer research, 2005-08, Vol.11 (16), p.5935-5941

2005

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A Phase I Trial of ISIS 2503, an Antisense Inhibitor of H-ras, in Combination with Gemcitabine in Patients with Advanced Cancer

Clinical cancer research, 2003-01, Vol.9 (1), p.115-123

2003

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A Phase Ib Study of the FGFR/VEGFR Inhibitor Dovitinib With Gemcitabine and Capecitabine in Advanced Solid Tumor and Pancreatic Cancer Patients

American journal of clinical oncology, 2019-02, Vol.42 (2), p.184-189

2019

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A phase I study of the histone deacetylase (HDAC) inhibitor entinostat, in combination with sorafenib in patients with advanced solid tumors

Investigational new drugs, 2015-02, Vol.33 (1), p.225-232

2015

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Phase 1 trial of tivantinib in combination with sorafenib in adult patients with advanced solid tumors

Investigational new drugs, 2015-02, Vol.33 (1), p.159-168

2015

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A phase II trial of the Src-kinase inhibitor saracatinib after four cycles of chemotherapy for patients with extensive stage small cell lung cancer: NCCTG trial N-0621

Lung cancer (Amsterdam, Netherlands), 2014-08, Vol.85 (2), p.245-250

2014

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Phase I Study of Rigosertib, an Inhibitor of the Phosphatidylinositol 3-Kinase and Polo-like Kinase 1 Pathways, Combined with Gemcitabine in Patients with Solid Tumors and Pancreatic Cancer

Clinical cancer research, 2012-04, Vol.18 (7), p.2048-2055

2012

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Long-Term Results of a Trial of Concurrent Chemotherapy and Escalating Doses of Radiation for Unresectable Non–Small Cell Lung Cancer: NCCTG N0028 (Alliance)

Journal of thoracic oncology, 2017-04, Vol.12 (4), p.697-703

2017

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A Randomized Phase II Study of Gemcitabine and Carboplatin with or without Cediranib as First-Line Therapy in Advanced Non–Small-Cell Lung Cancer: North Central Cancer Treatment Group Study N0528

Journal of thoracic oncology, 2013-01, Vol.8 (1), p.79-88

2013

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A Phase I Trial of the Farnesyl Protein Transferase Inhibitor R115777 in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer

Clinical cancer research, 2003-07, Vol.9 (7), p.2520-2526

2003

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A Phase I Trial of the Novel Farnesyl Protein Transferase Inhibitor, BMS-214662, in Combination with Paclitaxel and Carboplatin in Patients with Advanced Cancer

Clinical cancer research, 2005-03, Vol.11 (5), p.1877-1883

2005

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A Phase I/II Study of Bortezomib in Combination with Paclitaxel, Carboplatin, and Concurrent Thoracic Radiation Therapy for Non–Small-Cell Lung Cancer: North Central Cancer Treatment Group (NCCTG)-N0321

Journal of thoracic oncology, 2015-01, Vol.10 (1), p.172-180

2015

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Early Clinical Development of ARQ 197, a Selective, Non–ATP‐Competitive Inhibitor Targeting MET Tyrosine Kinase for the Treatment of Advanced Cancers

Pemetrexed (ALIMTA), A Novel Multitargeted Antineoplastic Agent

Advances in Chemotherapy of Non-small Cell Lung Cancer

Phase II Trial of Pemetrexed Plus Bevacizumab for Second-Line Therapy of Patients With Advanced Non–Small-Cell Lung Cancer: NCCTG and SWOG Study N0426

Crosstalk between hedgehog and other signaling pathways as a basis for combination therapies in cancer

Phase I Trial of Sorafenib in Combination with Gefitinib in Patients with Refractory or Recurrent Non–Small Cell Lung Cancer

Correlation Between Polymorphisms of the Reduced Folate Carrier Gene (SLC19A1) and Survival After Pemetrexed-Based Therapy in Non-small Cell Lung Cancer: A North Central Cancer Treatment Group-Based Exploratory Study

Evaluation of Lapatinib and Topotecan Combination Therapy: Tissue Culture, Murine Xenograft, and Phase I Clinical Trial Data

Results of combined‐modality therapy for limited‐stage small cell lung carcinoma in the elderly

A Randomized Double-Blind Phase II Study of the Seneca Valley Virus (NTX-010) versus Placebo for Patients with Extensive-Stage SCLC (ES SCLC) Who Were Stable or Responding after at Least Four Cycles of Platinum-Based Chemotherapy: North Central Cancer Treatment Group (Alliance) N0923 Study

Randomized Phase II Trial of Three Schedules of Pemetrexed and Gemcitabine As Front-Line Therapy for Advanced Non–Small-Cell Lung Cancer

Lung cancer. How much platinum-based chemotherapy is enough in NSCLC?

A phase IB dose-escalation study of the safety and pharmacokinetics of pictilisib in combination with either paclitaxel and carboplatin (with or without bevacizumab) or pemetrexed and cisplatin (with or without bevacizumab) in patients with advanced non–small cell lung cancer

Phase 1 Trial of Flavopiridol Combined with Cisplatin or Carboplatin in Patients with Advanced Malignancies with the Assessment of Pharmacokinetic and Pharmacodynamic End Points

A Phase I Trial of ISIS 2503, an Antisense Inhibitor of H-ras, in Combination with Gemcitabine in Patients with Advanced Cancer

A Phase Ib Study of the FGFR/VEGFR Inhibitor Dovitinib With Gemcitabine and Capecitabine in Advanced Solid Tumor and Pancreatic Cancer Patients

A phase I study of the histone deacetylase (HDAC) inhibitor entinostat, in combination with sorafenib in patients with advanced solid tumors

Phase 1 trial of tivantinib in combination with sorafenib in adult patients with advanced solid tumors

A phase II trial of the Src-kinase inhibitor saracatinib after four cycles of chemotherapy for patients with extensive stage small cell lung cancer: NCCTG trial N-0621

Phase I Study of Rigosertib, an Inhibitor of the Phosphatidylinositol 3-Kinase and Polo-like Kinase 1 Pathways, Combined with Gemcitabine in Patients with Solid Tumors and Pancreatic Cancer

Long-Term Results of a Trial of Concurrent Chemotherapy and Escalating Doses of Radiation for Unresectable Non–Small Cell Lung Cancer: NCCTG N0028 (Alliance)

A Randomized Phase II Study of Gemcitabine and Carboplatin with or without Cediranib as First-Line Therapy in Advanced Non–Small-Cell Lung Cancer: North Central Cancer Treatment Group Study N0528

A Phase I Trial of the Farnesyl Protein Transferase Inhibitor R115777 in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer

A Phase I Trial of the Novel Farnesyl Protein Transferase Inhibitor, BMS-214662, in Combination with Paclitaxel and Carboplatin in Patients with Advanced Cancer

A Phase I/II Study of Bortezomib in Combination with Paclitaxel, Carboplatin, and Concurrent Thoracic Radiation Therapy for Non–Small-Cell Lung Cancer: North Central Cancer Treatment Group (NCCTG)-N0321

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