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Versatility of Aminoglycosides and Prospects for Their Future

Clinical Microbiology Reviews, 2003-07, Vol.16 (3), p.430-450

2003

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The Class A β-Lactamase FTU-1 Is Native to Francisella tularensis

Antimicrobial Agents and Chemotherapy, 2012-02, Vol.56 (2), p.666-671

2012

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Novel Aminoglycoside 2″-Phosphotransferase Identified in a Gram-Negative Pathogen

Antimicrobial Agents and Chemotherapy, 2013-01, Vol.57 (1), p.452-457

2013

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A Novel Extended-Spectrum β-Lactamase, SGM-1, from an Environmental Isolate of Sphingobium sp

Antimicrobial Agents and Chemotherapy, 2013-08, Vol.57 (8), p.3783-3788

2013

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Multiplex PCR for Detection of Aminoglycoside Resistance Genes in Enterococci

Antimicrobial Agents and Chemotherapy, 2003-04, Vol.47 (4), p.1423-1426

2003

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Bulky “Gatekeeper” Residue Changes the Cosubstrate Specificity of Aminoglycoside 2″-Phosphotransferase IIa

Antimicrobial Agents and Chemotherapy, 2013-08, Vol.57 (8), p.3763-3766

2013

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Intrinsic Class D β-Lactamases of Clostridium difficile

mBio, 2018-12, Vol.9 (6)

2018

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Importance of Position 170 in the Inhibition of GES-Type β-Lactamases by Clavulanic Acid

Antimicrobial Agents and Chemotherapy, 2011-04, Vol.55 (4), p.1556-1562

2011

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Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D β-Lactamases

Antimicrobial agents and chemotherapy, 2019-02, Vol.63 (2)

2019

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Co-opting the Cell Wall in Fighting Methicillin-Resistant Staphylococcus aureus: Potent Inhibition of PBP 2a by Two Anti-MRSA β-Lactam Antibiotics

Journal of the American Chemical Society, 2008-07, Vol.130 (29), p.9212-9213

2008

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Mutant APH(2″)-IIa Enzymes with Increased Activity against Amikacin and Isepamicin

Antimicrobial Agents and Chemotherapy, 2010-04, Vol.54 (4), p.1590-1595

2010

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The role of conserved surface hydrophobic residues in the carbapenemase activity of the class D β‐lactamases

Acta crystallographica. Section D, Structural biology, 2017-08, Vol.73 (8), p.692-701

2017

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Mechanistic Basis for the Action of New Cephalosporin Antibiotics Effective against Methicillin- and Vancomycin-resistant Staphylococcus aureus

The Journal of biological chemistry, 2006-04, Vol.281 (15), p.10035-10041

2006

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The Basis for Resistance to β-Lactam Antibiotics by Penicillin-binding Protein 2a of Methicillin-resistant Staphylococcus aureus

The Journal of biological chemistry, 2004-09, Vol.279 (39), p.40802-40806

2004

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Cytoplasmic-Membrane Anchoring of a Class A β-Lactamase and Its Capacity in Manifesting Antibiotic Resistance

Antimicrobial Agents and Chemotherapy, 2007-08, Vol.51 (8), p.2937-2942

2007

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The C5α-Methyl-Substituted Carbapenem NA-1-157 Exhibits Potent Activity against Klebsiella spp. Isolates Producing OXA-48-Type Carbapenemases

ACS infectious diseases, 2023-05, Vol.9 (5), p.1123-1136

2023

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The l,d-Transpeptidase Ldt Ab from Acinetobacter baumannii Is Poorly Inhibited by Carbapenems and Has a Unique Structural Architecture

ACS infectious diseases, 2022-09, Vol.8 (9), p.1948-1961

2022

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Inhibition of the Clostridioides difficile Class D β‑Lactamase CDD‑1 by Avibactam

ACS infectious diseases, 2021-05, Vol.7 (5), p.1164-1176

2021

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Structural Basis for Carbapenemase Activity of the OXA-23 β-Lactamase from Acinetobacter baumannii

Chemistry & biology, 2013-09, Vol.20 (9), p.1107-1115

2013

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Selection and Characterization of β-Lactam–β-Lactamase Inactivator-Resistant Mutants following PCR Mutagenesis of the TEM-1 β-Lactamase Gene

Antimicrobial Agents and Chemotherapy, 1998-07, Vol.42 (7), p.1542-1548

1998

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Design of Novel Antibiotics that Bind to the Ribosomal Acyltransfer Site

Journal of the American Chemical Society, 2002-04, Vol.124 (13), p.3229-3237

2002

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Resistance to beta-lactam antibiotics and its mediation by the sensor domain of the transmembrane BlaR signaling pathway in Staphylococcus aureus

The Journal of biological chemistry, 2003-05, Vol.278 (20), p.18419-18425

2003

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Mutations in the aph(2")-Ic Gene Are Responsible for Increased Levels of Aminoglycoside Resistance

Antimicrobial Agents and Chemotherapy, 2002-10, Vol.46 (10), p.3253-3256

2002

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Versatility of Aminoglycosides and Prospects for Their Future

The Class A β-Lactamase FTU-1 Is Native to Francisella tularensis

Novel Aminoglycoside 2″-Phosphotransferase Identified in a Gram-Negative Pathogen

A Novel Extended-Spectrum β-Lactamase, SGM-1, from an Environmental Isolate of Sphingobium sp

Multiplex PCR for Detection of Aminoglycoside Resistance Genes in Enterococci

Bulky “Gatekeeper” Residue Changes the Cosubstrate Specificity of Aminoglycoside 2″-Phosphotransferase IIa

Intrinsic Class D β-Lactamases of Clostridium difficile

Importance of Position 170 in the Inhibition of GES-Type β-Lactamases by Clavulanic Acid

Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D β-Lactamases

Co-opting the Cell Wall in Fighting Methicillin-Resistant Staphylococcus aureus: Potent Inhibition of PBP 2a by Two Anti-MRSA β-Lactam Antibiotics

Mutant APH(2″)-IIa Enzymes with Increased Activity against Amikacin and Isepamicin

The role of conserved surface hydrophobic residues in the carbapenemase activity of the class D β‐lactamases

Mechanistic Basis for the Action of New Cephalosporin Antibiotics Effective against Methicillin- and Vancomycin-resistant Staphylococcus aureus

The Basis for Resistance to β-Lactam Antibiotics by Penicillin-binding Protein 2a of Methicillin-resistant Staphylococcus aureus

Cytoplasmic-Membrane Anchoring of a Class A β-Lactamase and Its Capacity in Manifesting Antibiotic Resistance

The C5α-Methyl-Substituted Carbapenem NA-1-157 Exhibits Potent Activity against Klebsiella spp. Isolates Producing OXA-48-Type Carbapenemases

The l,d-Transpeptidase Ldt Ab from Acinetobacter baumannii Is Poorly Inhibited by Carbapenems and Has a Unique Structural Architecture

Inhibition of the Clostridioides difficile Class D β‑Lactamase CDD‑1 by Avibactam

Structural Basis for Carbapenemase Activity of the OXA-23 β-Lactamase from Acinetobacter baumannii

Selection and Characterization of β-Lactam–β-Lactamase Inactivator-Resistant Mutants following PCR Mutagenesis of the TEM-1 β-Lactamase Gene

Design of Novel Antibiotics that Bind to the Ribosomal Acyltransfer Site

Resistance to beta-lactam antibiotics and its mediation by the sensor domain of the transmembrane BlaR signaling pathway in Staphylococcus aureus

Mutations in the aph(2")-Ic Gene Are Responsible for Increased Levels of Aminoglycoside Resistance

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