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Structure-activity relationships of GPR120 agonists based on a docking simulation

Molecular pharmacology, 2010-11, Vol.78 (5), p.804-810

2010

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Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis

Cell, 2019-11, Vol.179 (6), p.1289-1305.e21

2019

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Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects

Cell, 2014-10, Vol.159 (2), p.318-332

2014

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Preference for dietary fat: From detection to disease

Progress in lipid research, 2020-04, Vol.78, p.101032-101032, Article 101032

2020

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Free fatty acid receptor 4 responds to endogenous fatty acids to protect the heart from pressure overload

Cardiovascular research, 2022-03, Vol.118 (4), p.1061-1073

2022

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Functions of omega-3 fatty acids and FFA4 (GPR120) in macrophages

European journal of pharmacology, 2016-08, Vol.785, p.36-43

Im, Dong-Soon

2016

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Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation

Journal of neuroinflammation, 2017-04, Vol.14 (1), p.91-91, Article 91

2017

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Enzymatically-epoxidized docosahexaenoic acid, 19,20-EpDPE, suppresses hepatic crown-like structure formation and nonalcoholic steatohepatitis fibrosis through GPR120

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2023-03, Vol.1868 (3), p.159275-159275, Article 159275

2023

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Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120)

Bioorganic & medicinal chemistry letters, 2014-07, Vol.24 (14), p.3100-3103

2014

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Free-fatty acid receptor-4 (GPR120): Cellular and molecular function and its role in metabolic disorders

Biochemical pharmacology, 2016-06, Vol.110-111, p.1-15

Moniri, Nader H.

2016

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Free fatty acid receptor agonists for the treatment of type 2 diabetes: drugs in preclinical to phase II clinical development

Expert opinion on investigational drugs, 2016-08, Vol.25 (8), p.871-890

2016

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Short-term high fat feeding induces inflammatory responses of tuft cells and mucosal barrier cells in the murine stomach

Histology and histopathology, 2023-03, Vol.38 (3), p.273-286

2023

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Fat taste signal transduction and its possible negative modulator components

Progress in lipid research, 2020-07, Vol.79, p.101035-101035, Article 101035

2020

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Adaptive thermogenesis by dietary n-3 polyunsaturated fatty acids: Emerging evidence and mechanisms

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2019-01, Vol.1864 (1), p.59-70

2019

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Combined Deletion of Free Fatty-Acid Receptors 1 and 4 Minimally Impacts Glucose Homeostasis in Mice

Endocrinology (Philadelphia), 2021-03, Vol.162 (3), p.1

2021

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GPR120 (FFAR4) is preferentially expressed in pancreatic delta cells and regulates somatostatin secretion from murine islets of Langerhans

Diabetologia, 2014-06, Vol.57 (6), p.1182-1191

2014

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Free fatty acids-sensing G protein-coupled receptors in drug targeting and therapeutics

Current medicinal chemistry, 2013-10, Vol.20 (31), p.3855-3871

2013

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Omega-3 fatty acids in anti-inflammation (pro-resolution) and GPCRs

Progress in lipid research, 2012-07, Vol.51 (3), p.232-237

Im, Dong-Soon

2012

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GPR120 promotes neutrophil control of intestinal bacterial infection

Gut microbes, 2023-12, Vol.15 (1), p.2190311-2190311

2023

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Strain-level screening of human gut microbes identifies Blautia producta as a new anti-hyperlipidemic probiotic

Gut microbes, 2023-12, Vol.15 (1), p.2228045-2228045

2023

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An atlas of GPCRs in dopamine neurons: Identification of the free fatty acid receptor 4 as a regulator of food and water intake

Cell reports (Cambridge), 2024-07, Vol.43 (7), p.114509, Article 114509

2024

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Inhibition of GPR120 signaling in intestine ameliorates insulin resistance and fatty liver under high-fat diet feeding

American journal of physiology: endocrinology and metabolism, 2023-05, Vol.324 (5), p.E449-E460

2023

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Effects of Edible Oils with Different n‑6/n‑3 PUFA Ratios on Articular Cartilage Degeneration via Regulating the NF-κB Signaling Pathway

Journal of agricultural and food chemistry, 2020-11, Vol.68 (45), p.12641-12650

2020

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FFAR4: A New Player in Cardiometabolic Disease?

Endocrinology (Philadelphia), 2021-08, Vol.162 (8), p.1

2021

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9-PAHSA promotes browning of white fat via activating G-protein-coupled receptor 120 and inhibiting lipopolysaccharide / NF-kappa B pathway

Biochemical and biophysical research communications, 2018-11, Vol.506 (1), p.153-160

2018

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Structure-activity relationships of GPR120 agonists based on a docking simulation

Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis

Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects

Preference for dietary fat: From detection to disease

Free fatty acid receptor 4 responds to endogenous fatty acids to protect the heart from pressure overload

Functions of omega-3 fatty acids and FFA4 (GPR120) in macrophages

Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation

Enzymatically-epoxidized docosahexaenoic acid, 19,20-EpDPE, suppresses hepatic crown-like structure formation and nonalcoholic steatohepatitis fibrosis through GPR120

Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120)

Free-fatty acid receptor-4 (GPR120): Cellular and molecular function and its role in metabolic disorders

Free fatty acid receptor agonists for the treatment of type 2 diabetes: drugs in preclinical to phase II clinical development

Short-term high fat feeding induces inflammatory responses of tuft cells and mucosal barrier cells in the murine stomach

Fat taste signal transduction and its possible negative modulator components

Adaptive thermogenesis by dietary n-3 polyunsaturated fatty acids: Emerging evidence and mechanisms

Combined Deletion of Free Fatty-Acid Receptors 1 and 4 Minimally Impacts Glucose Homeostasis in Mice

GPR120 (FFAR4) is preferentially expressed in pancreatic delta cells and regulates somatostatin secretion from murine islets of Langerhans

Free fatty acids-sensing G protein-coupled receptors in drug targeting and therapeutics

Omega-3 fatty acids in anti-inflammation (pro-resolution) and GPCRs

GPR120 promotes neutrophil control of intestinal bacterial infection

Strain-level screening of human gut microbes identifies Blautia producta as a new anti-hyperlipidemic probiotic

An atlas of GPCRs in dopamine neurons: Identification of the free fatty acid receptor 4 as a regulator of food and water intake

Inhibition of GPR120 signaling in intestine ameliorates insulin resistance and fatty liver under high-fat diet feeding

Effects of Edible Oils with Different n‑6/n‑3 PUFA Ratios on Articular Cartilage Degeneration via Regulating the NF-κB Signaling Pathway

FFAR4: A New Player in Cardiometabolic Disease?

9-PAHSA promotes browning of white fat via activating G-protein-coupled receptor 120 and inhibiting lipopolysaccharide / NF-kappa B pathway

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