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Imaging tuberculosis with endogenous β-lactamase reporter enzyme fluorescence in live mice

Proceedings of the National Academy of Sciences - PNAS, 2010-07, Vol.107 (27), p.12239-12244

2010

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HaloTag protein-mediated specific labeling of living cells with quantum dots

Biochemical and biophysical research communications, 2008-09, Vol.374 (3), p.419-423

2008

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The conversion of oridonin to spirolactone-type or enmein-type diterpenoid: Synthesis and biological evaluation of ent-6,7-seco-oridonin derivatives as novel potential anticancer agents

European journal of medicinal chemistry, 2012-06, Vol.52, p.242-250

2012

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Synthesis and biological evaluation of ticagrelor derivatives as novel antiplatelet agents

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (11), p.3598-3602

2012

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Fluorescence imaging in vivo : recent advances

Current opinion in biotechnology, 2007-02, Vol.18 (1), p.17-25

2007

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Chiral separation, configurational identification and antihypertensive evaluation of (±)-7,8-dihydroxy-3-methyl-isochromanone-4

Bioorganic & medicinal chemistry letters, 2012-10, Vol.22 (20), p.6490-6493

2012

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Discovery of Novel Class I Histone Deacetylase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities

Journal of medicinal chemistry, 2015-10, Vol.58 (19), p.7672-7680

2015

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A Novel Potent Anticancer Compound Optimized from a Natural Oridonin Scaffold Induces Apoptosis and Cell Cycle Arrest through the Mitochondrial Pathway

Journal of medicinal chemistry, 2017-02, Vol.60 (4), p.1449-1468

2017

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Design, synthesis and biological evaluation of novel nitric oxide-donating protoberberine derivatives as antitumor agents

European journal of medicinal chemistry, 2017-05, Vol.132, p.173-183

2017

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Targeting the TGF-β signaling pathway: an updated patent review (2021-present)

Expert opinion on therapeutic patents, 2024-03, Vol.34 (3), p.99-126

2024

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Discovery of novel antitumor nitric oxide-donating β-elemene hybrids through inhibiting the PI3K/Akt pathway

European journal of medicinal chemistry, 2017-07, Vol.135, p.414-423

2017

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Identification of a Potent Oridonin Analogue for Treatment of Triple-Negative Breast Cancer

Journal of medicinal chemistry, 2020-08, Vol.63 (15), p.8157-8178

2020

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Design, Synthesis and Pharmacological Evaluation of Novel NO-Releasing Benzimidazole Hybrids as Potential Antihypertensive Candidate

Chemical biology & drug design, 2015-05, Vol.85 (5), p.541-548

2015

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Discovery of a Novel, Potent, Orally Active, and Safe Inhibitor Targeting Human Mitochondrial RNA Polymerase

Journal of medicinal chemistry, 2023-04, Vol.66 (7), p.5118-5153

2023

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Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site

Bioorganic chemistry, 2019-04, Vol.85, p.49-59

2019

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Design, synthesis, and biological evaluation of NAD(P)H: Quinone oxidoreductase (NQO1)-targeted oridonin prodrugs possessing indolequinone moiety for hypoxia-selective activation

European journal of medicinal chemistry, 2017-05, Vol.132, p.310-321

2017

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6,7-Seco-ent-Kauranoids Derived from Oridonin as Potential Anticancer Agents

Journal of natural products (Washington, D.C.), 2017-09, Vol.80 (9), p.2391-2398

2017

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Design, synthesis, and biological evaluation of 1,2,4-triazole bearing 5-substituted biphenyl-2-sulfonamide derivatives as potential antihypertensive candidates

Bioorganic & medicinal chemistry, 2013-12, Vol.21 (24), p.7742-7751

2013

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Synthesis, in vitro and in vivo antitumor activity of pyrazole-fused 23-hydroxybetulinic acid derivatives

Bioorganic & medicinal chemistry letters, 2015-02, Vol.25 (3), p.728-732

2015

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Bioluminogenic Substrate for In Vivo Imaging of β-Lactamase Activity

Angewandte Chemie (International ed.), 2007-01, Vol.46 (37), p.7031-7034

2007

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Design, synthesis and antitumor activity of triterpenoid pyrazine derivatives from 23-hydroxybetulinic acid

European journal of medicinal chemistry, 2015-06, Vol.97, p.235-244

2015

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Design, Synthesis, and Biological Evaluation of Novel Chromanone Derivatives as Multifunctional Agents for the Treatment of Alzheimer’s Disease

ACS chemical neuroscience, 2022-12, Vol.13 (23), p.3488-3501

2022

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Synthesis and antitumor activity of novel 3-oxo-23-hydroxybetulinic acid derivatives

European journal of medicinal chemistry, 2014-11, Vol.87, p.159-167

2014

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Synthesis and Biological Evaluation of Oxygen-containing Heterocyclic Ring-fused 23-Hydroxybetulinic Acid Derivatives as Antitumor Agents

Chemical biology & drug design, 2015-10, Vol.86 (4), p.424-431

2015

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Library Construction and Biological Evaluation of Enmein-Type Diterpenoid Analogues as Potential Anticancer Agents

ChemMedChem, 2013-05, Vol.8 (5), p.812-818

2013

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Imaging tuberculosis with endogenous β-lactamase reporter enzyme fluorescence in live mice

HaloTag protein-mediated specific labeling of living cells with quantum dots

The conversion of oridonin to spirolactone-type or enmein-type diterpenoid: Synthesis and biological evaluation of ent-6,7-seco-oridonin derivatives as novel potential anticancer agents

Synthesis and biological evaluation of ticagrelor derivatives as novel antiplatelet agents

Fluorescence imaging in vivo : recent advances

Chiral separation, configurational identification and antihypertensive evaluation of (±)-7,8-dihydroxy-3-methyl-isochromanone-4

Discovery of Novel Class I Histone Deacetylase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities

A Novel Potent Anticancer Compound Optimized from a Natural Oridonin Scaffold Induces Apoptosis and Cell Cycle Arrest through the Mitochondrial Pathway

Design, synthesis and biological evaluation of novel nitric oxide-donating protoberberine derivatives as antitumor agents

Targeting the TGF-β signaling pathway: an updated patent review (2021-present)

Discovery of novel antitumor nitric oxide-donating β-elemene hybrids through inhibiting the PI3K/Akt pathway

Identification of a Potent Oridonin Analogue for Treatment of Triple-Negative Breast Cancer

Design, Synthesis and Pharmacological Evaluation of Novel NO-Releasing Benzimidazole Hybrids as Potential Antihypertensive Candidate

Discovery of a Novel, Potent, Orally Active, and Safe Inhibitor Targeting Human Mitochondrial RNA Polymerase

Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site

Design, synthesis, and biological evaluation of NAD(P)H: Quinone oxidoreductase (NQO1)-targeted oridonin prodrugs possessing indolequinone moiety for hypoxia-selective activation

6,7-Seco-ent-Kauranoids Derived from Oridonin as Potential Anticancer Agents

Design, synthesis, and biological evaluation of 1,2,4-triazole bearing 5-substituted biphenyl-2-sulfonamide derivatives as potential antihypertensive candidates

Synthesis, in vitro and in vivo antitumor activity of pyrazole-fused 23-hydroxybetulinic acid derivatives

Bioluminogenic Substrate for In Vivo Imaging of β-Lactamase Activity

Design, synthesis and antitumor activity of triterpenoid pyrazine derivatives from 23-hydroxybetulinic acid

Design, Synthesis, and Biological Evaluation of Novel Chromanone Derivatives as Multifunctional Agents for the Treatment of Alzheimer’s Disease

Synthesis and antitumor activity of novel 3-oxo-23-hydroxybetulinic acid derivatives

Synthesis and Biological Evaluation of Oxygen-containing Heterocyclic Ring-fused 23-Hydroxybetulinic Acid Derivatives as Antitumor Agents

Library Construction and Biological Evaluation of Enmein-Type Diterpenoid Analogues as Potential Anticancer Agents

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