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Role of gangliosides in Alzheimer’s disease

Biochimica et biophysica acta, 2007-08, Vol.1768 (8), p.1943-1951

Yanagisawa, Katsuhiko

2007

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Pathological significance of ganglioside clusters in Alzheimer’s disease

Journal of neurochemistry, 2011-03, Vol.116 (5), p.806-812

Yanagisawa, Katsuhiko

2011

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Diabetes mellitus accelerates Aβ pathology in brain accompanied by enhanced GAβ generation in nonhuman primates

PloS one, 2015-02, Vol.10 (2), p.e0117362-e0117362

2015

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Alzheimer-type tau pathology in advanced aged nonhuman primate brains harboring substantial amyloid deposition

Brain research, 2010-02, Vol.1315, p.137-149

2010

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Retromer and Rab2‐dependent trafficking mediate PS1 degradation by proteasomes in endocytic disturbance

Journal of neurochemistry, 2016-05, Vol.137 (4), p.647-658

2016

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GM1 ganglioside and Alzheimer’s disease

Glycoconjugate journal, 2015-05, Vol.32 (3-4), p.87-91

Yanagisawa, Katsuhiko

2015

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Late endocytic dysfunction as a putative cause of amyloid fibril formation in Alzheimer's disease

Journal of neurochemistry, 2009-06, Vol.109 (5), p.1250-1260

2009

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Accelerated release of exosome-associated GM1 ganglioside (GM1) by endocytic pathway abnormality: another putative pathway for GM1-induced amyloid fibril formation

Journal of neurochemistry, 2008-04, Vol.105 (1), p.217-224

2008

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Altered Cholesterol Metabolism in Niemann-Pick Type C1 Mouse Brains Affects Mitochondrial Function

The Journal of biological chemistry, 2005-03, Vol.280 (12), p.11731-11739

2005

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A Seed for Alzheimer Amyloid in the Brain

The Journal of neuroscience, 2004-05, Vol.24 (20), p.4894-4902

2004

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Gangliosides determine the amyloid pathology of Alzheimerʼs disease

Neuroreport, 2009-08, Vol.20 (12), p.1043-1046

2009

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Apolipoprotein E (ApoE) Isoform-dependent Lipid Release from Astrocytes Prepared from Human ApoE3 and ApoE4 Knock-in Mice

The Journal of biological chemistry, 2002-08, Vol.277 (33), p.29919-29926

2002

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Gender effect on the accumulation of hyperphosphorylated tau in the brain of locus-ceruleus-injured APP-transgenic mouse

Neuroscience letters, 2010-01, Vol.468 (3), p.243-247

2010

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Apolipoprotein E Exhibits Isoform‐Specific Promotion of Lipid Efflux from Astrocytes and Neurons in Culture

Journal of neurochemistry, 2000-03, Vol.74 (3), p.1008-1016

2000

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Cholesterol-mediated Neurite Outgrowth Is Differently Regulated between Cortical and Hippocampal Neurons

The Journal of biological chemistry, 2005-12, Vol.280 (52), p.42759-42765

2005

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Modulation of Amyloid Precursor Protein Cleavage by Cellular Sphingolipids

The Journal of biological chemistry, 2004-03, Vol.279 (12), p.11984-11991

2004

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Cholesterol‐dependent modulation of tau phosphorylation in cultured neurons

Journal of neurochemistry, 2001-01, Vol.76 (2), p.391-400

2001

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Sphingomyelin accumulation provides a favorable milieu for GM1 ganglioside-induced assembly of amyloid β-protein

Neuroscience letters, 2010-09, Vol.481 (3), p.168-172

2010

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Cholesterol‐dependent modulation of dendrite outgrowth  and microtubule stability in cultured neurons

Journal of neurochemistry, 2002-01, Vol.80 (1), p.178-190

2002

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Age-dependent high-density clustering of GM1 ganglioside at presynaptic neuritic terminals promotes amyloid β-protein fibrillogenesis

Biochimica et biophysica acta, 2008-12, Vol.1778 (12), p.2717-2726

2008

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Soluble Aβ Oligomers Are Rapidly Sequestered from Brain ISF In Vivo and Bind GM1 Ganglioside on Cellular Membranes

Neuron (Cambridge, Mass.), 2014-04, Vol.82 (2), p.308-319

2014

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Site-specific Phosphorylation of Tau Accompanied by Activation of Mitogen-activated Protein Kinase (MAPK) in Brains of Niemann-Pick Type C Mice

The Journal of biological chemistry, 2001-03, Vol.276 (13), p.10314-10319

2001

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Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice

Neuroreport, 2002-03, Vol.13 (4), p.383-386

2002

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Macrophage Plasma Membrane Cholesterol Contributes to Brucella abortus Infection of Mice

Infection and Immunity, 2002-09, Vol.70 (9), p.4818-4825

2002

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Endosomal accumulation of GM1 ganglioside-bound amyloid β-protein in neurons of aged monkey brains

Neuroreport, 2007-10, Vol.18 (16), p.1669-1673

2007

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Role of gangliosides in Alzheimer’s disease

Pathological significance of ganglioside clusters in Alzheimer’s disease

Diabetes mellitus accelerates Aβ pathology in brain accompanied by enhanced GAβ generation in nonhuman primates

Alzheimer-type tau pathology in advanced aged nonhuman primate brains harboring substantial amyloid deposition

Retromer and Rab2‐dependent trafficking mediate PS1 degradation by proteasomes in endocytic disturbance

GM1 ganglioside and Alzheimer’s disease

Late endocytic dysfunction as a putative cause of amyloid fibril formation in Alzheimer's disease

Accelerated release of exosome-associated GM1 ganglioside (GM1) by endocytic pathway abnormality: another putative pathway for GM1-induced amyloid fibril formation

Altered Cholesterol Metabolism in Niemann-Pick Type C1 Mouse Brains Affects Mitochondrial Function

A Seed for Alzheimer Amyloid in the Brain

Gangliosides determine the amyloid pathology of Alzheimerʼs disease

Apolipoprotein E (ApoE) Isoform-dependent Lipid Release from Astrocytes Prepared from Human ApoE3 and ApoE4 Knock-in Mice

Gender effect on the accumulation of hyperphosphorylated tau in the brain of locus-ceruleus-injured APP-transgenic mouse

Apolipoprotein E Exhibits Isoform‐Specific Promotion of Lipid Efflux from Astrocytes and Neurons in Culture

Cholesterol-mediated Neurite Outgrowth Is Differently Regulated between Cortical and Hippocampal Neurons

Modulation of Amyloid Precursor Protein Cleavage by Cellular Sphingolipids

Cholesterol‐dependent modulation of tau phosphorylation in cultured neurons

Sphingomyelin accumulation provides a favorable milieu for GM1 ganglioside-induced assembly of amyloid β-protein

Cholesterol‐dependent modulation of dendrite outgrowth  and microtubule stability in cultured neurons

Age-dependent high-density clustering of GM1 ganglioside at presynaptic neuritic terminals promotes amyloid β-protein fibrillogenesis

Soluble Aβ Oligomers Are Rapidly Sequestered from Brain ISF In Vivo and Bind GM1 Ganglioside on Cellular Membranes

Site-specific Phosphorylation of Tau Accompanied by Activation of Mitogen-activated Protein Kinase (MAPK) in Brains of Niemann-Pick Type C Mice

Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice

Macrophage Plasma Membrane Cholesterol Contributes to Brucella abortus Infection of Mice

Endosomal accumulation of GM1 ganglioside-bound amyloid β-protein in neurons of aged monkey brains

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