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Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures

Nature communications, 2021-01, Vol.12 (1), p.115-115, Article 115

2021

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Structural and biological insights into Klebsiella pneumoniae surface polysaccharide degradation by a bacteriophage K1 lyase: implications for clinical use

Journal of biomedical science, 2022-02, Vol.29 (1), p.9-9, Article 9

2022

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Pharmacokinetic alterations of rhubarb anthraquinones in experimental colitis induced by dextran sulfate sodium in the rat

Journal of ethnopharmacology, 2017-02, Vol.198, p.600-607

2017

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In Vitro Pharmacokinetic Characterization of Mulberroside A, the Main Polyhydroxylated Stilbene in Mulberry (Morus alba L.), and Its Bacterial Metabolite Oxyresveratrol in Traditional Oral Use

Journal of agricultural and food chemistry, 2012-03, Vol.60 (9), p.2299-2308

2012

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Trastuzumab cardiotoxicity: from clinical trials to experimental studies

British journal of pharmacology, 2017-11, Vol.174 (21), p.3727-3748

2017

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Modular organization of SARS coronavirus nucleocapsid protein

Journal of biomedical science, 2006-01, Vol.13 (1), p.59-72

2006

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Effects of Matrine and Oxymatrine on Catalytic Activity of Cytochrome P450s in Rats

Basic & clinical pharmacology & toxicology, 2010-11, Vol.107 (5), p.906-913

2010

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Trastuzumab alters the expression of genes essential for cardiac function and induces ultrastructural changes of cardiomyocytes in mice

PloS one, 2013-11, Vol.8 (11), p.e79543

2013

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Particle size effect of curcumin nanosuspensions on cytotoxicity, cellular internalization, in vivo pharmacokinetics and biodistribution

Nanomedicine, 2017-04, Vol.13 (3), p.943-953

2017

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Development of Novel Irreversible Pyruvate Kinase M2 Inhibitors

Journal of medicinal chemistry, 2019-09, Vol.62 (18), p.8497-8510

2019

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Development and regulation of monoclonal antibody products: challenges and opportunities

Cancer and metastasis reviews, 2005-12, Vol.24 (4), p.569-584

2005

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Ado-Trastuzumab Emtansine Targets Hepatocytes Via Human Epidermal Growth Factor Receptor 2 to Induce Hepatotoxicity

Molecular cancer therapeutics, 2016-03, Vol.15 (3), p.480-490

2016

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The dimer interface of the SARS coronavirus nucleocapsid protein adapts a porcine respiratory and reproductive syndrome virus-like structure

FEBS letters, 2005-10, Vol.579 (25), p.5663-5668

2005

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How a Low-Fidelity DNA Polymerase Chooses Non-Watson–Crick from Watson–Crick Incorporation

Journal of the American Chemical Society, 2014-04, Vol.136 (13), p.4927-4937

2014

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Insulin activation of vacuolar protein sorting 34 mediates localized phosphatidylinositol 3-phosphate production at lamellipodia and activation of mTOR/S6K1

Cellular signalling, 2014-06, Vol.26 (6), p.1258-1268

2014

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Growth and motility inhibition of breast cancer cells by epidermal growth factor receptor degradation is correlated with inactivation of Cdc42

Cancer research (Chicago, Ill.), 2006-04, Vol.66 (7), p.3523-3530

2006

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The γ-subunit of the coatomer complex binds Cdc42 to mediate transformation

Nature (London), 2000-06, Vol.405 (6788), p.800-804

2000

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Epidermal Growth Factor-dependent Regulation of Cdc42 Is Mediated by the Src Tyrosine Kinase

The Journal of biological chemistry, 2003-12, Vol.278 (49), p.49293-49300

2003

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Trastuzumab, but Not Pertuzumab, Dysregulates HER2 Signaling to Mediate Inhibition of Autophagy and Increase in Reactive Oxygen Species Production in Human Cardiomyocytes

Molecular cancer therapeutics, 2016-06, Vol.15 (6), p.1321-1331

2016

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Cdc42 and Ras Cooperate to Mediate Cellular Transformation by Intersectin-L

The Journal of biological chemistry, 2005-06, Vol.280 (24), p.22883-22891

2005

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pp60c-Src Phosphorylates and Activates Vacuolar Protein Sorting 34 to Mediate Cellular Transformation

Cancer research (Chicago, Ill.), 2010-07, Vol.70 (14), p.5974-5983

2010

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Cdc42 Stimulates RNA Splicing via the S6 Kinase and a Novel S6 Kinase Target, the Nuclear Cap-binding Complex

The Journal of biological chemistry, 2000-12, Vol.275 (48), p.37307-37310

2000

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Identification of a Putative Effector for Cdc42Hs with High Sequence Similarity to the RasGAP-related Protein IQGAP1 and a Cdc42Hs Binding Partner with Similarity to IQGAP2

The Journal of biological chemistry, 1996-09, Vol.271 (36), p.21732-21737

1996

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The Presystemic Interplay between Gut Microbiota and Orally Administered Calycosin-7-O-β-D-Glucoside

Drug metabolism and disposition, 2015-10, Vol.43 (10), p.1601-1611

2015

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Cardiotoxicity of ErbB2-targeted therapies and its impact on drug development, a spotlight on trastuzumab

Expert opinion on drug metabolism & toxicology, 2017-07, Vol.13 (7), p.755-766

2017

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Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures

Structural and biological insights into Klebsiella pneumoniae surface polysaccharide degradation by a bacteriophage K1 lyase: implications for clinical use

Pharmacokinetic alterations of rhubarb anthraquinones in experimental colitis induced by dextran sulfate sodium in the rat

In Vitro Pharmacokinetic Characterization of Mulberroside A, the Main Polyhydroxylated Stilbene in Mulberry (Morus alba L.), and Its Bacterial Metabolite Oxyresveratrol in Traditional Oral Use

Trastuzumab cardiotoxicity: from clinical trials to experimental studies

Modular organization of SARS coronavirus nucleocapsid protein

Effects of Matrine and Oxymatrine on Catalytic Activity of Cytochrome P450s in Rats

Trastuzumab alters the expression of genes essential for cardiac function and induces ultrastructural changes of cardiomyocytes in mice

Particle size effect of curcumin nanosuspensions on cytotoxicity, cellular internalization, in vivo pharmacokinetics and biodistribution

Development of Novel Irreversible Pyruvate Kinase M2 Inhibitors

Development and regulation of monoclonal antibody products: challenges and opportunities

Ado-Trastuzumab Emtansine Targets Hepatocytes Via Human Epidermal Growth Factor Receptor 2 to Induce Hepatotoxicity

The dimer interface of the SARS coronavirus nucleocapsid protein adapts a porcine respiratory and reproductive syndrome virus-like structure

How a Low-Fidelity DNA Polymerase Chooses Non-Watson–Crick from Watson–Crick Incorporation

Insulin activation of vacuolar protein sorting 34 mediates localized phosphatidylinositol 3-phosphate production at lamellipodia and activation of mTOR/S6K1

Growth and motility inhibition of breast cancer cells by epidermal growth factor receptor degradation is correlated with inactivation of Cdc42

The γ-subunit of the coatomer complex binds Cdc42 to mediate transformation

Epidermal Growth Factor-dependent Regulation of Cdc42 Is Mediated by the Src Tyrosine Kinase

Trastuzumab, but Not Pertuzumab, Dysregulates HER2 Signaling to Mediate Inhibition of Autophagy and Increase in Reactive Oxygen Species Production in Human Cardiomyocytes

Cdc42 and Ras Cooperate to Mediate Cellular Transformation by Intersectin-L

pp60c-Src Phosphorylates and Activates Vacuolar Protein Sorting 34 to Mediate Cellular Transformation

Cdc42 Stimulates RNA Splicing via the S6 Kinase and a Novel S6 Kinase Target, the Nuclear Cap-binding Complex

Identification of a Putative Effector for Cdc42Hs with High Sequence Similarity to the RasGAP-related Protein IQGAP1 and a Cdc42Hs Binding Partner with Similarity to IQGAP2

The Presystemic Interplay between Gut Microbiota and Orally Administered Calycosin-7-O-β-D-Glucoside

Cardiotoxicity of ErbB2-targeted therapies and its impact on drug development, a spotlight on trastuzumab

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