UB Paderborn / Katalog / Suche / in CDI

Es ist ein Fehler in der Kommunikation mit einem externen System aufgetreten. Bitte versuchen Sie Ihre letzte Aktion erneut. Sollte der Fehler bestehen bleiben, setzen Sie sich bitte mit dem Informationszentrum der Bibliothek in Verbindung oder versuchen Sie es später erneut.

1 – 25 von 32

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

SHR1032, a novel STING agonist, stimulates anti-tumor immunity and directly induces AML apoptosis

Scientific reports, 2022-05, Vol.12 (1), p.8579-12, Article 8579

2022

Volltextzugriff (PDF)

Mechanistically Probing Lipid-siRNA Nanoparticle-associated Toxicities Identifies Jak Inhibitors Effective in Mitigating Multifaceted Toxic Responses

Molecular therapy, 2011-03, Vol.19 (3), p.567-575

2011

Volltextzugriff (PDF)

Nucleocytoplasmic Shuttling of Oncoprotein Hdm2 Is Required for Hdm2-Mediated Degradation of p53

Proceedings of the National Academy of Sciences - PNAS, 1999-03, Vol.96 (6), p.3077-3080

1999

Volltextzugriff (PDF)

The Mitotic Checkpoint in Cancer Therapy

Cell cycle (Georgetown, Tex.), 2005-11, Vol.4 (11), p.1495-1499

Tao, Weikang

2005

Volltextzugriff (PDF)

Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer

European journal of pharmaceutical sciences, 2017-12, Vol.110, p.51-61

2017

Volltextzugriff (PDF)

Kinesin spindle protein (KSP) inhibitors. Part 4: Structure-based design of 5-alkylamino-3,5-diaryl-4,5-dihydropyrazoles as potent, water-soluble inhibitors of the mitotic kinesin KSP

Bioorganic & medicinal chemistry letters, 2006-06, Vol.16 (12), p.3175-3179

2006

Volltextzugriff (PDF)

Development of 6-substituted indolylquinolinones as potent Chek1 kinase inhibitors

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (22), p.5907-5912

2006

Volltextzugriff (PDF)

Kinesin spindle protein (KSP) inhibitors. Part 3: Synthesis and evaluation of phenolic 2,4-diaryl-2,5-dihydropyrroles with reduced hERG binding and employment of a phosphate prodrug strategy for aqueous solubility

Bioorganic & medicinal chemistry letters, 2006-04, Vol.16 (7), p.1780-1783

2006

Volltextzugriff (PDF)

Discovery of A Novel EGFR-Targeting Antibody-Drug Conjugate, SHR-A1307, for the Treatment of Solid Tumors Resistant or Refractory to Anti-EGFR Therapies

Molecular cancer therapeutics, 2019-06, Vol.18 (6), p.1104-1114

2019

Volltextzugriff (PDF)

Biodistribution of Small Interfering RNA at the Organ and Cellular Levels after Lipid Nanoparticle-mediated Delivery

The journal of histochemistry and cytochemistry, 2011-08, Vol.59 (8), p.727-740

2011

Volltextzugriff (PDF)

Discovery of novel spiro compound as RAF kinase inhibitor with in vitro potency against KRAS mutant cancer

Bioorganic & medicinal chemistry letters, 2022-05, Vol.63, p.128666-128666, Article 128666

2022

Volltextzugriff (PDF)

Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (20), p.5671-5676

2007

Volltextzugriff (PDF)

Discovery of 2‑(Ortho-Substituted Benzyl)-Indole Derivatives as Potent and Orally Bioavailable RORγ Agonists with Antitumor Activity

Journal of medicinal chemistry, 2021-10, Vol.64 (20), p.14983-14996

2021

Volltextzugriff (PDF)

Discovery of spiro amide SHR902275: A potent, selective, and efficacious RAF inhibitor targeting RAS mutant cancers

European journal of medicinal chemistry, 2022-01, Vol.228, p.114040-114040, Article 114040

2022

Volltextzugriff (PDF)

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

Proceedings of the National Academy of Sciences - PNAS, 1999-06, Vol.96 (12), p.6937-6941

1999

Volltextzugriff (PDF)

Discovery of EBI-907: A highly potent and orally active B-Raf(V600E) inhibitor for the treatment of melanoma and associated cancers

Bioorganic & medicinal chemistry letters, 2016-02, Vol.26 (3), p.819-823

2016

Volltextzugriff (PDF)

Noninvasive Imaging of Lipid Nanoparticle–Mediated Systemic Delivery of Small-Interfering RNA to the Liver

Molecular therapy, 2010-09, Vol.18 (9), p.1657-1666

2010

Volltextzugriff (PDF)

EBI-907, a novel BRAF(V600E) inhibitor, has potent oral anti-tumor activity and a broad kinase selectivity profile

Cancer biology & therapy, 2016-01, Vol.17 (2), p.199-207

2016

Volltextzugriff (PDF)

Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1

Genes & development, 2001-07, Vol.15 (14), p.1796-1807

2001

Volltextzugriff (PDF)

Visualization of Mitotic Arrest of Cell Cycle with Bioluminescence Imaging in Living Animals

Molecular imaging and biology, 2013-08, Vol.15 (4), p.431-440

2013

Volltextzugriff (PDF)

Quantification of Cy-5 siRNA signal in the intra-vital multi-photon microscopy images

2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2012-01, Vol.2012, p.3712-3715

2012

Volltextzugriff (PDF)

Oligomerized Ced-4 Kills Budding Yeast through a Caspase-Independent Mechanism

Biochemical and biophysical research communications, 1999-07, Vol.260 (3), p.799-805

1999

Volltextzugriff (PDF)

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1

Oncogene, 2023-01, Vol.42 (2), p.83-98

2023

Volltextzugriff (PDF)

Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration

Nature communications, 2020-11, Vol.11 (1), p.5990-14, Article 5990

2020

Volltextzugriff (PDF)

Polydatin impairs mitochondria fitness and ameliorates podocyte injury by suppressing Drp1 expression

Journal of cellular physiology, 2017-10, Vol.232 (10), p.2776-2787

2017

Volltextzugriff (PDF)

1 – 25 von 32

Suche als RSS-Feed

Aktive Filter

ThemaAnimals

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(30)
Mit Volltextzugriff
(31)

Publikationsform

Artikel
(32)

Sprache

Englisch
(32)

Erscheinungsjahr

n.n

Thema

14 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

SHR1032, a novel STING agonist, stimulates anti-tumor immunity and directly induces AML apoptosis

Mechanistically Probing Lipid-siRNA Nanoparticle-associated Toxicities Identifies Jak Inhibitors Effective in Mitigating Multifaceted Toxic Responses

Nucleocytoplasmic Shuttling of Oncoprotein Hdm2 Is Required for Hdm2-Mediated Degradation of p53

The Mitotic Checkpoint in Cancer Therapy

Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer

Kinesin spindle protein (KSP) inhibitors. Part 4: Structure-based design of 5-alkylamino-3,5-diaryl-4,5-dihydropyrazoles as potent, water-soluble inhibitors of the mitotic kinesin KSP

Development of 6-substituted indolylquinolinones as potent Chek1 kinase inhibitors

Kinesin spindle protein (KSP) inhibitors. Part 3: Synthesis and evaluation of phenolic 2,4-diaryl-2,5-dihydropyrroles with reduced hERG binding and employment of a phosphate prodrug strategy for aqueous solubility

Discovery of A Novel EGFR-Targeting Antibody-Drug Conjugate, SHR-A1307, for the Treatment of Solid Tumors Resistant or Refractory to Anti-EGFR Therapies

Biodistribution of Small Interfering RNA at the Organ and Cellular Levels after Lipid Nanoparticle-mediated Delivery

Discovery of novel spiro compound as RAF kinase inhibitor with in vitro potency against KRAS mutant cancer

Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP

Discovery of 2‑(Ortho-Substituted Benzyl)-Indole Derivatives as Potent and Orally Bioavailable RORγ Agonists with Antitumor Activity

Discovery of spiro amide SHR902275: A potent, selective, and efficacious RAF inhibitor targeting RAS mutant cancers

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

Discovery of EBI-907: A highly potent and orally active B-Raf(V600E) inhibitor for the treatment of melanoma and associated cancers

Noninvasive Imaging of Lipid Nanoparticle–Mediated Systemic Delivery of Small-Interfering RNA to the Liver

EBI-907, a novel BRAF(V600E) inhibitor, has potent oral anti-tumor activity and a broad kinase selectivity profile

Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1

Visualization of Mitotic Arrest of Cell Cycle with Bioluminescence Imaging in Living Animals

Quantification of Cy-5 siRNA signal in the intra-vital multi-photon microscopy images

Oligomerized Ced-4 Kills Budding Yeast through a Caspase-Independent Mechanism

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1

Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration

Polydatin impairs mitochondria fitness and ameliorates podocyte injury by suppressing Drp1 expression

Aktive Filter

Suchergebnisse filtern