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Glucocorticoids and cardiovascular disease

European journal of endocrinology, 2007-11, Vol.157 (5), p.545

Walker, Brian R

2007

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Glucocorticoids Acutely Increase Brown Adipose Tissue Activity in Humans, Revealing Species-Specific Differences in UCP-1 Regulation

Cell metabolism, 2016-07, Vol.24 (1), p.130-141

2016

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Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source

Nature cell biology, 2014-04, Vol.16 (4), p.367

2014

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11β-HSD1 Inhibitors for the Treatment of Type 2 Diabetes and Cardiovascular Disease

Drugs (New York, N.Y.), 2013-09, Vol.73 (13), p.1385-1393

2013

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11β-HSD1 inhibition does not affect murine tumour angiogenesis but may exert a selective effect on tumour growth by modulating inflammation and fibrosis

PloS one, 2023-03, Vol.18 (3), p.e0255709-e0255709

2023

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Mass Spectrometry Imaging for Dissecting Steroid Intracrinology within Target Tissues

Analytical chemistry (Washington), 2013-12, Vol.85 (23), p.11576-11584

2013

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5α-Reductase type 1 deficiency or inhibition predisposes to insulin resistance, hepatic steatosis, and liver fibrosis in rodents

Diabetes (New York, N.Y.), 2015-02, Vol.64 (2), p.447-458

2015

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Intergenerational consequences of fetal programming by in utero exposure to glucocorticoids in rats

American journal of physiology. Regulatory, integrative and comparative physiology, 2005-01, Vol.288 (1), p.R34-R38

2005

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Deletion of the Androgen Receptor in Adipose Tissue in Male Mice Elevates Retinol Binding Protein 4 and Reveals Independent Effects on Visceral Fat Mass and on Glucose Homeostasis

Diabetes (New York, N.Y.), 2012-05, Vol.61 (5), p.1072-1081

2012

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Maternal Obesity Has Little Effect on the Immediate Offspring but Impacts on the Next Generation

Endocrinology (Philadelphia), 2013-07, Vol.154 (7), p.2514-2524

2013

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A Choline-Deficient Diet Exacerbates Fatty Liver but Attenuates Insulin Resistance and Glucose Intolerance in Mice Fed a High-Fat Diet

Diabetes (New York, N.Y.), 2006-07, Vol.55 (7), p.2015-2020

2006

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Novel Adipose Tissue–Mediated Resistance to Diet-Induced Visceral Obesity in 11β-Hydroxysteroid Dehydrogenase Type 1–Deficient Mice

Diabetes (New York, N.Y.), 2004-04, Vol.53 (4), p.931-938

2004

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ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy

Science translational medicine, 2016-08, Vol.8 (352), p.352ra109

2016

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11β-Hydroxysteroid Dehydrogenase Type 1 Is Expressed in Neutrophils and Restrains an Inflammatory Response in Male Mice

Endocrinology (Philadelphia), 2016-07, Vol.157 (7), p.2928-2936

2016

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Elevated hepatic 11β-hydroxysteroid dehydrogenase type 1 induces insulin resistance in uremia

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (10), p.3817-3822

2014

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Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice

Molecular metabolism (Germany), 2021-06, Vol.48, p.101225, Article 101225

2021

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Metabolic pathways promoting intrahepatic fatty acid accumulation in methionine and choline deficiency: implications for the pathogenesis of steatohepatitis

American journal of physiology: endocrinology and metabolism, 2011-02, Vol.300 (2), p.E402-E409

2011

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Quantitative 3-dimensional imaging of murine neointimal and atherosclerotic lesions by optical projection tomography

PloS one, 2011-02, Vol.6 (2), p.e16906-e16906

2011

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Memory deficits in a juvenile rat model of type 1 diabetes are due to excess 11β-HSD1 activity, which is upregulated by high glucose concentrations rather than insulin deficiency

Diabetologia, 2023-09, Vol.66 (9), p.1735-1747

2023

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Cognitive and Disease-Modifying Effects of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer's Disease

Endocrinology (Philadelphia), 2015-12, Vol.156 (12), p.4592-4603

2015

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Selection and early clinical evaluation of the brain‐penetrant 11β‐hydroxysteroid dehydrogenase type 1 (11β‐HSD1) inhibitor UE2343 (Xanamem™)

British journal of pharmacology, 2017-03, Vol.174 (5), p.396-408

2017

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Dysregulation of glucocorticoid metabolism in murine obesity: comparable effects of leptin resistance and deficiency

Journal of endocrinology, 2009-05, Vol.201 (2), p.211-218

2009

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Comparison of mechanisms of angiostasis caused by the anti-inflammatory steroid 5α-tetrahydrocorticosterone versus conventional glucocorticoids

European journal of pharmacology, 2022-08, Vol.929, p.175111-175111, Article 175111

2022

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Effects of proportions of dietary macronutrients on glucocorticoid metabolism in diet-induced obesity in rats

PloS one, 2010-01, Vol.5 (1), p.e8779-e8779

2010

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Dysregulation of Cortisol Metabolism in Equine Pituitary Pars Intermedia Dysfunction

Endocrinology (Philadelphia), 2018-11, Vol.159 (11), p.3791-3800

2018

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Glucocorticoids and cardiovascular disease

Glucocorticoids Acutely Increase Brown Adipose Tissue Activity in Humans, Revealing Species-Specific Differences in UCP-1 Regulation

Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source

11β-HSD1 Inhibitors for the Treatment of Type 2 Diabetes and Cardiovascular Disease

11β-HSD1 inhibition does not affect murine tumour angiogenesis but may exert a selective effect on tumour growth by modulating inflammation and fibrosis

Mass Spectrometry Imaging for Dissecting Steroid Intracrinology within Target Tissues

5α-Reductase type 1 deficiency or inhibition predisposes to insulin resistance, hepatic steatosis, and liver fibrosis in rodents

Intergenerational consequences of fetal programming by in utero exposure to glucocorticoids in rats

Deletion of the Androgen Receptor in Adipose Tissue in Male Mice Elevates Retinol Binding Protein 4 and Reveals Independent Effects on Visceral Fat Mass and on Glucose Homeostasis

Maternal Obesity Has Little Effect on the Immediate Offspring but Impacts on the Next Generation

A Choline-Deficient Diet Exacerbates Fatty Liver but Attenuates Insulin Resistance and Glucose Intolerance in Mice Fed a High-Fat Diet

Novel Adipose Tissue–Mediated Resistance to Diet-Induced Visceral Obesity in 11β-Hydroxysteroid Dehydrogenase Type 1–Deficient Mice

ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy

11β-Hydroxysteroid Dehydrogenase Type 1 Is Expressed in Neutrophils and Restrains an Inflammatory Response in Male Mice

Elevated hepatic 11β-hydroxysteroid dehydrogenase type 1 induces insulin resistance in uremia

Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice

Metabolic pathways promoting intrahepatic fatty acid accumulation in methionine and choline deficiency: implications for the pathogenesis of steatohepatitis

Quantitative 3-dimensional imaging of murine neointimal and atherosclerotic lesions by optical projection tomography

Memory deficits in a juvenile rat model of type 1 diabetes are due to excess 11β-HSD1 activity, which is upregulated by high glucose concentrations rather than insulin deficiency

Cognitive and Disease-Modifying Effects of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer's Disease

Selection and early clinical evaluation of the brain‐penetrant 11β‐hydroxysteroid dehydrogenase type 1 (11β‐HSD1) inhibitor UE2343 (Xanamem™)

Dysregulation of glucocorticoid metabolism in murine obesity: comparable effects of leptin resistance and deficiency

Comparison of mechanisms of angiostasis caused by the anti-inflammatory steroid 5α-tetrahydrocorticosterone versus conventional glucocorticoids

Effects of proportions of dietary macronutrients on glucocorticoid metabolism in diet-induced obesity in rats

Dysregulation of Cortisol Metabolism in Equine Pituitary Pars Intermedia Dysfunction

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