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Molecular etiology of atherogenesis--in vitro induction of lipidosis in macrophages with a new LDL model

PloS one, 2012-04, Vol.7 (4), p.e34822

2012

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A tag-free collisionally induced fragmentation approach to detect drug-adducted proteins by mass spectrometry

Rapid communications in mass spectrometry, 2015-11, Vol.29 (22), p.2175-2183

2015

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Epoxidation of Olefins by Cytochrome P450: Evidence from Site-Specific Mutagenesis for Hydroperoxo-Iron as an Electrophilic Oxidant

Proceedings of the National Academy of Sciences - PNAS, 1998-03, Vol.95 (7), p.3555-3560

1998

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Deuterium isotope effects on drug pharmacokinetics. I. System-dependent effects of specific deuteration with aldehyde oxidase cleared drugs

Drug metabolism and disposition, 2012-03, Vol.40 (3), p.625-634

2012

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Discovery of Azetidinyl Ketolides for the Treatment of Susceptible and Multidrug Resistant Community-Acquired Respiratory Tract Infections

Journal of medicinal chemistry, 2009-12, Vol.52 (23), p.7446-7457

2009

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On the Mechanism of Action of Cytochrome P450: Evaluation of Hydrogen Abstraction in Oxygen-Dependent Alcohol Oxidation

Biochemistry (Easton), 1994-05, Vol.33 (21), p.6442-6449

1994

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Discrete Species of Activated Oxygen Yield Different Cytochrome P450 Heme Adducts from Aldehydes

Biochemistry (Easton), 1999-08, Vol.38 (32), p.10511-10518

1999

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Peroxo-Iron and Oxenoid-Iron Species as Alternative Oxygenating Agents in Cytochrome P450-Catalyzed Reactions: Switching by Threonine-302 to Alanine Mutagenesis of Cytochrome P450 2B4

Proceedings of the National Academy of Sciences - PNAS, 1996-05, Vol.93 (10), p.4644-4648

1996

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The use of 18O-exchange and base-catalyzed N-dealkylation with liquid chromatography/tandem mass spectrometry to identify carbinolamide metabolites

Rapid communications in mass spectrometry, 2010-07, Vol.24 (14), p.2151-2161

2010

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Aromatization of a Bicyclic Steroid Analog, 3-Oxodecalin-4-ene-10-carboxaldehyde, by Liver Microsomal Cytochrome P450 2B4

Biochemistry (Easton), 1994-11, Vol.33 (46), p.13651-13661

1994

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1,2,3-Thiadiazole: A Novel Heterocyclic Heme Ligand for the Design of Cytochrome P450 Inhibitors

Biochemistry (Easton), 1997-06, Vol.36 (23), p.7209-7216

1997

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Inactivation of Ethanol-Inducible Cytochrome P450 and Other Microsomal P450 Isozymes by Trans-4-Hydroxy-2-Nonenal, a Major Product of Membrane Lipid Peroxidation

Proceedings of the National Academy of Sciences - PNAS, 1995-04, Vol.92 (9), p.3764-3768

1995

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Significance of Glycine 478 in the Metabolism of N-Benzyl-1-aminobenzotriazole to Reactive Intermediates by Cytochrome P450 2B1

Biochemistry (Easton), 1997-09, Vol.36 (39), p.11707-11716

1997

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Cytochrome P450: progress and predictions

The FASEB journal, 1992-01, Vol.6 (2), p.669-673

1992

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Catalysis by Cytochrome P-450 of an Oxidative Reaction in Xenobiotic Aldehyde Metabolism: Deformylation with Olefin Formation

Proceedings of the National Academy of Sciences - PNAS, 1991-10, Vol.88 (20), p.8963-8966

1991

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Metabolic Activation of trans-4-Hydroxy-2-nonenal, a Toxic Product of Membrane Lipid Peroxidation and Inhibitor of P450 Cytochromes

The Journal of biological chemistry, 1997-09, Vol.272 (36), p.22611-22616

1997

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In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes

Drug metabolism and disposition, 2003-10, Vol.31 (10), p.1240

2003

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Evidence for a Role of a Perferryl-Oxygen Complex, FeO3+, in the N-Oxygenation of Amines by Cytochrome P450 Enzymes

Molecular pharmacology, 1997-01, Vol.51 (1), p.147-151

1997

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Reductive β-Scission of the Hydroperoxides of Fatty Acids and Xenobiotics: Role of Alcohol-Inducible Cytochrome P-450

Proceedings of the National Academy of Sciences - PNAS, 1990-07, Vol.87 (14), p.5499-5503

1990

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Adrenal proteins bound by a reactive intermediate of mitotane

Cancer chemotherapy and pharmacology, 1997, Vol.39 (6), p.537-540

1997

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Hydrocarbon Formation in the Reductive Cleavage of Hydroperoxides by Cytochrome P-450

Proceedings of the National Academy of Sciences - PNAS, 1987-03, Vol.84 (5), p.1172-1176

1987

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Multiple activated oxygen species in P450 catalysis: contributions To specificity in drug metabolism

Drug metabolism and disposition, 1998-12, Vol.26 (12), p.1190

1998

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Role of isozymes of rabbit microsomal cytochrome P-450 in the metabolism of retinoic acid, retinol, and retinal

Molecular pharmacology, 1992-02, Vol.41 (2), p.427-433

1992

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Affinity labeling of bovine opsin by trans-retinoyl chloromethane

Biochemical and biophysical research communications, 1989-04, Vol.160 (2), p.942-947

1989

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[28] Reductive cleavage of hydroperoxides by cytochrome P-450

Methods in Enzymology, 1990, Vol.186, p.278-282

1990

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Molecular etiology of atherogenesis--in vitro induction of lipidosis in macrophages with a new LDL model

A tag-free collisionally induced fragmentation approach to detect drug-adducted proteins by mass spectrometry

Epoxidation of Olefins by Cytochrome P450: Evidence from Site-Specific Mutagenesis for Hydroperoxo-Iron as an Electrophilic Oxidant

Deuterium isotope effects on drug pharmacokinetics. I. System-dependent effects of specific deuteration with aldehyde oxidase cleared drugs

Discovery of Azetidinyl Ketolides for the Treatment of Susceptible and Multidrug Resistant Community-Acquired Respiratory Tract Infections

On the Mechanism of Action of Cytochrome P450: Evaluation of Hydrogen Abstraction in Oxygen-Dependent Alcohol Oxidation

Discrete Species of Activated Oxygen Yield Different Cytochrome P450 Heme Adducts from Aldehydes

Peroxo-Iron and Oxenoid-Iron Species as Alternative Oxygenating Agents in Cytochrome P450-Catalyzed Reactions: Switching by Threonine-302 to Alanine Mutagenesis of Cytochrome P450 2B4

The use of 18O-exchange and base-catalyzed N-dealkylation with liquid chromatography/tandem mass spectrometry to identify carbinolamide metabolites

Aromatization of a Bicyclic Steroid Analog, 3-Oxodecalin-4-ene-10-carboxaldehyde, by Liver Microsomal Cytochrome P450 2B4

1,2,3-Thiadiazole: A Novel Heterocyclic Heme Ligand for the Design of Cytochrome P450 Inhibitors

Inactivation of Ethanol-Inducible Cytochrome P450 and Other Microsomal P450 Isozymes by Trans-4-Hydroxy-2-Nonenal, a Major Product of Membrane Lipid Peroxidation

Significance of Glycine 478 in the Metabolism of N-Benzyl-1-aminobenzotriazole to Reactive Intermediates by Cytochrome P450 2B1

Cytochrome P450: progress and predictions

Catalysis by Cytochrome P-450 of an Oxidative Reaction in Xenobiotic Aldehyde Metabolism: Deformylation with Olefin Formation

Metabolic Activation of trans-4-Hydroxy-2-nonenal, a Toxic Product of Membrane Lipid Peroxidation and Inhibitor of P450 Cytochromes

In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes

Evidence for a Role of a Perferryl-Oxygen Complex, FeO3+, in the N-Oxygenation of Amines by Cytochrome P450 Enzymes

Reductive β-Scission of the Hydroperoxides of Fatty Acids and Xenobiotics: Role of Alcohol-Inducible Cytochrome P-450

Adrenal proteins bound by a reactive intermediate of mitotane

Hydrocarbon Formation in the Reductive Cleavage of Hydroperoxides by Cytochrome P-450

Multiple activated oxygen species in P450 catalysis: contributions To specificity in drug metabolism

Role of isozymes of rabbit microsomal cytochrome P-450 in the metabolism of retinoic acid, retinol, and retinal

Affinity labeling of bovine opsin by trans-retinoyl chloromethane

[28] Reductive cleavage of hydroperoxides by cytochrome P-450

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