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Selenosugars targeting the infective stage of Trypanosoma brucei with high selectivity

International journal for parasitology -- drugs and drug resistance, 2024-04, Vol.24, p.100529-100529, Article 100529

2024

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Diglycosyl diselenides alter redox homeostasis and glucose consumption of infective African trypanosomes

International journal for parasitology -- drugs and drug resistance, 2017-12, Vol.7 (3), p.303-313

2017

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Bivalent O-glycoside mimetics with S/disulfide/Se substitutions and aromatic core: Synthesis, molecular modeling and inhibitory activity on biomedically relevant lectins in assays of increasing physiological relevance

Bioorganic & medicinal chemistry, 2017-06, Vol.25 (12), p.3158-3170

2017

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Anoxia leads to a rapid translocation of human trypsinogen 4 to the plasma membrane of cultured astrocytes

Journal of neurochemistry, 2010-10, Vol.115 (2), p.314-324

2010

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Aromatic glycosyl disulfide derivatives: Evaluation of their inhibitory activities against Trypanosoma cruzi

Bioorganic & medicinal chemistry letters, 2013-06, Vol.23 (12), p.3576-3579

2013

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Soluble Jagged-1 is able to inhibit the function of its multivalent form to induce hematopoietic stem cell self-renewal in a surrogate in vitro assay

Journal of leukocyte biology, 2004-04, Vol.75 (4), p.714-720

2004

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Efficient inhibition of muscle and liver glycogen phosphorylases by a new glucopyranosylidene-spiro-thiohydantoin

Bioorganic & medicinal chemistry letters, 1999-05, Vol.9 (10), p.1385-1390

1999

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Myelin basic protein, an autoantigen in multiple sclerosis, is selectively processed by human trypsin 4

FEBS letters, 2006-01, Vol.580 (2), p.545-552

2006

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Two Mutations in Rat Trypsin Confer Resistance against Autolysis

Biochemical and biophysical research communications, 1998-02, Vol.243 (1), p.56-60

1998

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Solution conformations of an insect neuropeptide: Crustacean cardioactive peptide (CCAP)

Peptides (New York, N.Y. : 1980), 2009-03, Vol.30 (3), p.557-564

2009

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Anopheles gambiae, Anoga-HrTH hormone, free and bound structure – A nuclear magnetic resonance experiment

Peptides (New York, N.Y. : 1980), 2013-03, Vol.41, p.94-100

2013

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Visible light induces matrix metalloproteinase-9 expression in rat eye

Journal of neurochemistry, 2007-12, Vol.103 (6), p.2224-2233

2007

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Attempts to convert chymotrypsin to trypsin

FEBS letters, 1996-01, Vol.379 (2), p.143-147

1996

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Crystal structure reveals basis for the inhibitor resistance of human brain trypsin

Journal of molecular biology, 2002-02, Vol.315 (5), p.1209-1218

2002

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Enzyme:Substrate Hydrogen Bond Shortening during the Acylation Phase of Serine Protease Catalysis

Biochemistry (Easton), 2006-02, Vol.45 (7), p.2114-2121

2006

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Effects of Serpin Binding on the Target Proteinase: Global Stabilization, Localized Increased Structural Flexibility, and Conserved Hydrogen Bonding at the Active Site

Biochemistry (Easton), 1997-05, Vol.36 (18), p.5455-5464

1997

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Cloning and expression of ostrich trypsinogen: an avian trypsin with a highly sensitive autolysis site

Biochimica et biophysica acta, 2005-04, Vol.1748 (1), p.35-42

2005

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Kinetic and Crystallographic Studies of Glucopyranosylidene Spirothiohydantoin Binding to Glycogen Phosphorylase b

Bioorganic & medicinal chemistry, 2002-02, Vol.10 (2), p.261-268

2002

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Serum amyloid A in geese; cloning and expression of recombinant protein

Amyloid, 2005-06, Vol.12 (2), p.109-114

2005

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The Role of Disulfide Bond C191-C220 in Trypsin and Chymotrypsin

Biochemical and biophysical research communications, 1997-01, Vol.230 (3), p.592-596

1997

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Electrostatic Complementarity within the Substrate-Binding Pocket of Trypsin

Proceedings of the National Academy of Sciences - PNAS, 1988-07, Vol.85 (14), p.4961-4965

1988

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Inositol 1,4,5-trisphosphate receptor subtypes in adrenal glomerulosa cells

Endocrinology (Philadelphia), 1994-06, Vol.134 (6), p.2354-2359

1994

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Change of reactivity of lysine residues upon actin polymerization

Biochemistry (Easton), 1981-09, Vol.20 (20), p.5914-5919

1981

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Conformational transitions in the myosin head induced by temperature, nucleotide and actin: studies on subfragment-1 of myosins from rabbit and frog fast skeletal muscle with a limited proteolysis method

European journal of biochemistry, 1987-06, Vol.165 (2), p.353-362

1987

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In situ gelation of thiolated poly(aspartic acid) derivatives through oxidant-free disulfide formation for ophthalmic drug delivery

Colloids and surfaces, B, Biointerfaces, 2023-05, Vol.225, p.113254-113254, Article 113254

2023

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Selenosugars targeting the infective stage of Trypanosoma brucei with high selectivity

Diglycosyl diselenides alter redox homeostasis and glucose consumption of infective African trypanosomes

Bivalent O-glycoside mimetics with S/disulfide/Se substitutions and aromatic core: Synthesis, molecular modeling and inhibitory activity on biomedically relevant lectins in assays of increasing physiological relevance

Anoxia leads to a rapid translocation of human trypsinogen 4 to the plasma membrane of cultured astrocytes

Aromatic glycosyl disulfide derivatives: Evaluation of their inhibitory activities against Trypanosoma cruzi

Soluble Jagged-1 is able to inhibit the function of its multivalent form to induce hematopoietic stem cell self-renewal in a surrogate in vitro assay

Efficient inhibition of muscle and liver glycogen phosphorylases by a new glucopyranosylidene-spiro-thiohydantoin

Myelin basic protein, an autoantigen in multiple sclerosis, is selectively processed by human trypsin 4

Two Mutations in Rat Trypsin Confer Resistance against Autolysis

Solution conformations of an insect neuropeptide: Crustacean cardioactive peptide (CCAP)

Anopheles gambiae, Anoga-HrTH hormone, free and bound structure – A nuclear magnetic resonance experiment

Visible light induces matrix metalloproteinase-9 expression in rat eye

Attempts to convert chymotrypsin to trypsin

Crystal structure reveals basis for the inhibitor resistance of human brain trypsin

Enzyme:Substrate Hydrogen Bond Shortening during the Acylation Phase of Serine Protease Catalysis

Effects of Serpin Binding on the Target Proteinase: Global Stabilization, Localized Increased Structural Flexibility, and Conserved Hydrogen Bonding at the Active Site

Cloning and expression of ostrich trypsinogen: an avian trypsin with a highly sensitive autolysis site

Kinetic and Crystallographic Studies of Glucopyranosylidene Spirothiohydantoin Binding to Glycogen Phosphorylase b

Serum amyloid A in geese; cloning and expression of recombinant protein

The Role of Disulfide Bond C191-C220 in Trypsin and Chymotrypsin

Electrostatic Complementarity within the Substrate-Binding Pocket of Trypsin

Inositol 1,4,5-trisphosphate receptor subtypes in adrenal glomerulosa cells

Change of reactivity of lysine residues upon actin polymerization

Conformational transitions in the myosin head induced by temperature, nucleotide and actin: studies on subfragment-1 of myosins from rabbit and frog fast skeletal muscle with a limited proteolysis method

In situ gelation of thiolated poly(aspartic acid) derivatives through oxidant-free disulfide formation for ophthalmic drug delivery

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