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An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials

Drug metabolism and disposition, 2019-06, Vol.47 (6), p.601-615

2019

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Antitumor Benzothiazoles. 7. Synthesis of 2-(4-Acylaminophenyl)benzothiazoles and Investigations into the Role of Acetylation in the Antitumor Activities of the Parent Amines

Journal of medicinal chemistry, 1999-02, Vol.42 (3), p.381-392

1999

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Molecular aspects of chemical carcinogenesis: The roles of oncogenes and tumour suppressor genes

Toxicology, 1995-02, Vol.96 (3), p.173-194

Stanley, Lesley A.

1995

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Delayed effects of tamoxifen in hepatocarcinogenesis-resistant Fischer 344 rats as compared with susceptible strains

Cancer letters, 2001-09, Vol.171 (1), p.27-35

2001

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Metabolic polymorphisms and cancer susceptibility

Cancer surveys, 1995, Vol.25, p.27

1995

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Immunochemical detection of arylamine N-acetyltransferase in normal and neoplastic bladder

The journal of histochemistry and cytochemistry, 1996-09, Vol.44 (9), p.1059-1067

1996

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New lipid and lipoprotein targets for the treatment of cardiometabolic diseases

Journal of lipid research, 2012-09, Vol.53 (9), p.1719-1721

2012

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PXR and CAR: Nuclear Receptors which Play a Pivotal Role in Drug Disposition and Chemical Toxicity

Drug metabolism reviews, 2006-01, Vol.38 (3), p.515-597

2006

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Cloning and tissue-specific expression of the cDNA for the mouse Clara cell 10 kD protein: comparison of endogenous expression to rabbit uteroglobin promoter-driven transgene expression

American journal of respiratory cell and molecular biology, 1993-09, Vol.9 (3), p.231-238

1993

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Mutations associated with in vivo aflatoxin B1-induced carcinogenesis need not be present in the in vitro transformations by this toxin

Cancer letters, 1999-04, Vol.137 (2), p.173-181

1999

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Expression of SV40 T antigen under control of rabbit uteroglobin promoter in transgenic mice

American journal of physiology. Lung cellular and molecular physiology, 1991-08, Vol.261 (2), p.70-L76

1991

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Differential effects of recombinant interferon α on constitutive and inducible cytochrome P450 isozymes in mouse liver

Biochemical pharmacology, 1991-07, Vol.42 (2), p.311-320

1991

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Ras mutations in methylclofenapate-induced B6C3F1 and C57BL/10J mouse liver tumours

Carcinogenesis (New York), 1994-06, Vol.15 (6), p.1125-1131

1994

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A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site

Blood, 2012-12, Vol.120 (24), p.4859-4868

2012

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Cytoplasmic β-actin promoter produces germ cell and preimplantation embryonic transgene expression

Molecular reproduction and development, 1993-02, Vol.34 (2), p.117-126

1993

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Association of tamoxifen biliary excretion rate with prior tamoxifen exposure and increased mdr1b expression

Biochemical pharmacology, 2000-07, Vol.60 (2), p.233-239

2000

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Potentiation and suppression of mouse liver cytochrome P‐450 isozymes during the acute‐phase response induced by bacterial endotoxin

European journal of biochemistry, 1988-05, Vol.174 (1), p.31-36

1988

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Immunochemical detection of arylamine N-acetyltransferase during mouse embryonic development and in adult mouse brain

Teratology (Philadelphia), 1998-11, Vol.58 (5), p.174-182

1998

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Proto-oncogene activation in liver tumors of hepatocarcinogenesis-resistant strains of mice

Carcinogenesis (New York), 1992-12, Vol.13 (12), p.2427-2433

1992

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Xenogenetics in multifactorial disease susceptibility

Trends in genetics, 1995-12, Vol.11 (12), p.509-512

1995

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Localization of polymorphic N-acetyltransferase (NAT2) in tissues of inbred mice

Pharmacogenetics (London), 1997-04, Vol.7 (2), p.121-130

1997

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Dysanaptic growth of conducting airways after pneumonectomy assessed by CT scan

Journal of applied physiology (1985), 2002-10, Vol.93 (4), p.1235-1242

2002

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Cancer Research and Clinical Trial in Action: An Important Exercise Before You Embark on Your Study

Cancer Clinical Trials: Proactive Strategies, 2007, Vol.132, p.291-309

2007

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Lymphatic Markers, Tumour Lymphangiogenesis and Lymph Node Metastasis

Cancer Metastasis And The Lymphovascular System: Basis For Rational Therapy, 2007, Vol.135, p.39-53

2007

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Significance of Regional Draining Lymph Nodes in the Development of Tumor Immunity: Implications for Cancer Immunotherapy

Cancer Metastasis And The Lymphovascular System: Basis For Rational Therapy, 2007, Vol.135, p.223-237

2007

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An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials

Antitumor Benzothiazoles. 7. Synthesis of 2-(4-Acylaminophenyl)benzothiazoles and Investigations into the Role of Acetylation in the Antitumor Activities of the Parent Amines

Molecular aspects of chemical carcinogenesis: The roles of oncogenes and tumour suppressor genes

Delayed effects of tamoxifen in hepatocarcinogenesis-resistant Fischer 344 rats as compared with susceptible strains

Metabolic polymorphisms and cancer susceptibility

Immunochemical detection of arylamine N-acetyltransferase in normal and neoplastic bladder

New lipid and lipoprotein targets for the treatment of cardiometabolic diseases

PXR and CAR: Nuclear Receptors which Play a Pivotal Role in Drug Disposition and Chemical Toxicity

Cloning and tissue-specific expression of the cDNA for the mouse Clara cell 10 kD protein: comparison of endogenous expression to rabbit uteroglobin promoter-driven transgene expression

Mutations associated with in vivo aflatoxin B1-induced carcinogenesis need not be present in the in vitro transformations by this toxin

Expression of SV40 T antigen under control of rabbit uteroglobin promoter in transgenic mice

Differential effects of recombinant interferon α on constitutive and inducible cytochrome P450 isozymes in mouse liver

Ras mutations in methylclofenapate-induced B6C3F1 and C57BL/10J mouse liver tumours

A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site

Cytoplasmic β-actin promoter produces germ cell and preimplantation embryonic transgene expression

Association of tamoxifen biliary excretion rate with prior tamoxifen exposure and increased mdr1b expression

Potentiation and suppression of mouse liver cytochrome P‐450 isozymes during the acute‐phase response induced by bacterial endotoxin

Immunochemical detection of arylamine N-acetyltransferase during mouse embryonic development and in adult mouse brain

Proto-oncogene activation in liver tumors of hepatocarcinogenesis-resistant strains of mice

Xenogenetics in multifactorial disease susceptibility

Localization of polymorphic N-acetyltransferase (NAT2) in tissues of inbred mice

Dysanaptic growth of conducting airways after pneumonectomy assessed by CT scan

Cancer Research and Clinical Trial in Action: An Important Exercise Before You Embark on Your Study

Lymphatic Markers, Tumour Lymphangiogenesis and Lymph Node Metastasis

Significance of Regional Draining Lymph Nodes in the Development of Tumor Immunity: Implications for Cancer Immunotherapy

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