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MTHFR deficiency or reduced intake of folate or choline in pregnant mice results in impaired short-term memory and increased apoptosis in the hippocampus of wild-type offspring

Neuroscience, 2015-08, Vol.300, p.1-9

2015

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Oncogenic role of PDK4 in human colon cancer cells

British journal of cancer, 2017-03, Vol.116 (7), p.930-936

2017

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A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development

Human molecular genetics, 2013-09, Vol.22 (18), p.3705-3719

2013

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Dietary and genetic compromise in folate availability reduces acetylcholine, cognitive performance and increases aggression: Critical role of S-adenosyl methionine

The Journal of nutrition, health & aging, 2008-04, Vol.12 (4), p.252-261

2008

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Molecular genetics of methylenetetrahydrofolate reductase deficiency

Journal of inherited metabolic disease, 1996, Vol.19 (5), p.589-594

ROZEN, R

1996

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Methylenetetrahydrofolate reductase (MTHFR): a novel target for cancer therapy

Current pharmaceutical design, 2008-04, Vol.14 (11), p.1143-1150

2008

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Betaine supplementation improves the atherogenic risk factor profile in a transgenic mouse model of hyperhomocysteinemia

Atherosclerosis, 2007-12, Vol.195 (2), p.e100-e107

2007

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Methylenetetrahydrofolate reductase (MTHFR) deficiency enhances resistance against cytomegalovirus infection

Genes and immunity, 2009-10, Vol.10 (7), p.662-666

2009

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Mefolinate (5-methyltetrahydrofolate), but not folic acid, decreases mortality in an animal model of severe methylenetetrahydrofolate reductase deficiency

Journal of inherited metabolic disease, 2008-06, Vol.31 (3), p.403-411

2008

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Effects of Common Polymorphisms on the Properties of Recombinant Human Methylenetetrahydrofolate Reductase

Proceedings of the National Academy of Sciences - PNAS, 2001-12, Vol.98 (26), p.14853-14858

2001

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Elevated Homocysteine Reduces Apolipoprotein A-I Expression in Hyperhomocysteinemic Mice and in Males With Coronary Artery Disease

Circulation research, 2006-03, Vol.98 (4), p.564-571

2006

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Infertility in 5,10-Methylenetetrahydrofolate Reductase (MTHFR)-Deficient Male Mice Is Partially Alleviated by Lifetime Dietary Betaine Supplementation

Biology of reproduction, 2005-03, Vol.72 (3), p.667-677

2005

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Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition

Human molecular genetics, 2001-03, Vol.10 (5), p.433-443

2001

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Effect of Mthfr genotype on diet-induced hyperhomocysteinemia and vascular function in mice

Blood, 2004-04, Vol.103 (7), p.2624-2629

2004

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Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency

Journal of cellular biochemistry, 2008-10, Vol.105 (2), p.467-476

2008

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Maternal methylenetetrahydrofolate reductase deficiency and low dietary folate lead to adverse reproductive outcomes and congenital heart defects in mice

The American journal of clinical nutrition, 2005-07, Vol.82 (1), p.188-195

2005

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Homocysteine‐betaine interactions in a murine model of 5,10‐methylenetetrahydrofolate reductase deficiency

The FASEB journal, 2003-03, Vol.17 (3), p.1-25

2003

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Mice Deficient in Methylenetetrahydrofolate Reductase Exhibit Tissue-Specific Distribution of Folates

The Journal of nutrition, 2004-11, Vol.134 (11), p.2975-2978

2004

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Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR)

Mammalian genome, 1998-08, Vol.9 (8), p.652-656

1998

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Betaine rescue of an animal model with methylenetetrahydrofolate reductase deficiency

Biochemical journal, 2004-09, Vol.382 (Pt 3), p.831-840

2004

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Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification

Nature genetics, 1994-06, Vol.7 (2), p.195-200

1994

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Effect of hyperhomocystinemia and hypertension on endothelial function in methylenetetrahydrofolate reductase-deficient mice

Arteriosclerosis, thrombosis, and vascular biology, 2003-08, Vol.23 (8), p.1352-1357

2003

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Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice

Carcinogenesis (New York), 2002-01, Vol.23 (1), p.61-65

2002

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Postnatal cerebellar defects in mice deficient in methylenetetrahydrofolate reductase

International journal of developmental neuroscience, 2005-08, Vol.23 (5), p.465-474

2005

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Poor Cell Surface Expression of Human Melanocortin-4 Receptor Mutations Associated with Obesity

The Journal of biological chemistry, 2003-06, Vol.278 (25), p.22939-22945

2003

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MTHFR deficiency or reduced intake of folate or choline in pregnant mice results in impaired short-term memory and increased apoptosis in the hippocampus of wild-type offspring

Oncogenic role of PDK4 in human colon cancer cells

A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development

Dietary and genetic compromise in folate availability reduces acetylcholine, cognitive performance and increases aggression: Critical role of S-adenosyl methionine

Molecular genetics of methylenetetrahydrofolate reductase deficiency

Methylenetetrahydrofolate reductase (MTHFR): a novel target for cancer therapy

Betaine supplementation improves the atherogenic risk factor profile in a transgenic mouse model of hyperhomocysteinemia

Methylenetetrahydrofolate reductase (MTHFR) deficiency enhances resistance against cytomegalovirus infection

Mefolinate (5-methyltetrahydrofolate), but not folic acid, decreases mortality in an animal model of severe methylenetetrahydrofolate reductase deficiency

Effects of Common Polymorphisms on the Properties of Recombinant Human Methylenetetrahydrofolate Reductase

Elevated Homocysteine Reduces Apolipoprotein A-I Expression in Hyperhomocysteinemic Mice and in Males With Coronary Artery Disease

Infertility in 5,10-Methylenetetrahydrofolate Reductase (MTHFR)-Deficient Male Mice Is Partially Alleviated by Lifetime Dietary Betaine Supplementation

Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition

Effect of Mthfr genotype on diet-induced hyperhomocysteinemia and vascular function in mice

Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency

Maternal methylenetetrahydrofolate reductase deficiency and low dietary folate lead to adverse reproductive outcomes and congenital heart defects in mice

Homocysteine‐betaine interactions in a murine model of 5,10‐methylenetetrahydrofolate reductase deficiency

Mice Deficient in Methylenetetrahydrofolate Reductase Exhibit Tissue-Specific Distribution of Folates

Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR)

Betaine rescue of an animal model with methylenetetrahydrofolate reductase deficiency

Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification

Effect of hyperhomocystinemia and hypertension on endothelial function in methylenetetrahydrofolate reductase-deficient mice

Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice

Postnatal cerebellar defects in mice deficient in methylenetetrahydrofolate reductase

Poor Cell Surface Expression of Human Melanocortin-4 Receptor Mutations Associated with Obesity

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