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αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor

PloS one, 2015-07, Vol.10 (7), p.e0132737-e0132737

2015

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Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with Rin

BMC neuroscience, 2005-08, Vol.6 (1), p.53-53, Article 53

2005

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Reelin and the Cdc42/Rac1 guanine nucleotide exchange factor αPIX/Arhgef6 promote dendritic Golgi translocation in hippocampal neurons

The European journal of neuroscience, 2013-05, Vol.37 (9), p.1404-1412

2013

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Duplication of Glu37 in the switch I region of HRAS impairs effector/GAP binding and underlies Costello syndrome by promoting enhanced growth factor-dependent MAPK and AKT activation

Human molecular genetics, 2010-03, Vol.19 (5), p.790-802

2010

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RASopathy-Associated CBL Germline Mutations Cause Aberrant Ubiquitylation and Trafficking of EGFR

Human mutation, 2014-11, Vol.35 (11), p.1372-1381

2014

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WDR11, a WD Protein that Interacts with Transcription Factor EMX1, Is Mutated in Idiopathic Hypogonadotropic Hypogonadism and Kallmann Syndrome

American journal of human genetics, 2010-10, Vol.87 (4), p.465-479

2010

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Genetic Variants in ARHGEF6 Cause Congenital Anomalies of the Kidneys and Urinary Tract in Humans, Mice, and Frogs

Journal of the American Society of Nephrology, 2023-02, Vol.34 (2), p.273-290

2023

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Dysregulation of Rho GTPases in the αPix/Arhgef6 mouse model of X-linked intellectual disability is paralleled by impaired structural and synaptic plasticity and cognitive deficits

Human molecular genetics, 2012-01, Vol.21 (2), p.268-286

2012

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Functional analysis of a duplication (p.E63_D69dup) in the switch II region of HRAS: new aspects of the molecular pathogenesis underlying Costello syndrome

Human molecular genetics, 2013-04, Vol.22 (8), p.1643-1653

2013

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Mutations of the Mitochondrial Holocytochrome c–Type Synthase in X-Linked Dominant Microphthalmia with Linear Skin Defects Syndrome

American journal of human genetics, 2006-11, Vol.79 (5), p.878-889

2006

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A novel HRAS substitution (c.266C>G; p.S89C) resulting in decreased downstream signaling suggests a new dimension of RAS pathway dysregulation in human development

American journal of medical genetics. Part A, 2012-09, Vol.158A (9), p.2106-2118

2012

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AlphaPIX and betaPIX and their role in focal adhesion formation

European journal of cell biology, 2006-04, Vol.85 (3-4), p.265-274

2006

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Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling

Human molecular genetics, 2003-01, Vol.12 (2), p.155-167

2003

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The MYC dualism in growth and death

Mutation Research-Reviews in Mutation Research, 1999-11, Vol.437 (3), p.205-217

1999

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Red blood cell-derived semaphorin 7A promotes thrombo-inflammation in myocardial ischemia-reperfusion injury through platelet GPIb

Nature communications, 2020-03, Vol.11 (1), p.1315-1315, Article 1315

2020

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Bone marrow-derived human mesenchymal stem cells express cardiomyogenic proteins but do not exhibit functional cardiomyogenic differentiation potential

Stem cells and development, 2012-09, Vol.21 (13), p.2457-2470

2012

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αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor

Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with Rin

Reelin and the Cdc42/Rac1 guanine nucleotide exchange factor αPIX/Arhgef6 promote dendritic Golgi translocation in hippocampal neurons

Duplication of Glu37 in the switch I region of HRAS impairs effector/GAP binding and underlies Costello syndrome by promoting enhanced growth factor-dependent MAPK and AKT activation

RASopathy-Associated CBL Germline Mutations Cause Aberrant Ubiquitylation and Trafficking of EGFR

WDR11, a WD Protein that Interacts with Transcription Factor EMX1, Is Mutated in Idiopathic Hypogonadotropic Hypogonadism and Kallmann Syndrome

Genetic Variants in ARHGEF6 Cause Congenital Anomalies of the Kidneys and Urinary Tract in Humans, Mice, and Frogs

Dysregulation of Rho GTPases in the αPix/Arhgef6 mouse model of X-linked intellectual disability is paralleled by impaired structural and synaptic plasticity and cognitive deficits

Functional analysis of a duplication (p.E63_D69dup) in the switch II region of HRAS: new aspects of the molecular pathogenesis underlying Costello syndrome

Mutations of the Mitochondrial Holocytochrome c–Type Synthase in X-Linked Dominant Microphthalmia with Linear Skin Defects Syndrome

A novel HRAS substitution (c.266C>G; p.S89C) resulting in decreased downstream signaling suggests a new dimension of RAS pathway dysregulation in human development

AlphaPIX and betaPIX and their role in focal adhesion formation

Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling

The MYC dualism in growth and death

Red blood cell-derived semaphorin 7A promotes thrombo-inflammation in myocardial ischemia-reperfusion injury through platelet GPIb

Bone marrow-derived human mesenchymal stem cells express cardiomyogenic proteins but do not exhibit functional cardiomyogenic differentiation potential

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