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Cell death in chronic inflammation: breaking the cycle to treat rheumatic disease

Nature reviews. Rheumatology, 2020-09, Vol.16 (9), p.496-513

2020

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Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma

Nature immunology, 2021-07, Vol.22 (7), p.851

2021

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TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells

Cell reports (Cambridge), 2020-04, Vol.31 (1), p.107492, Article 107492

2020

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RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

Nature communications, 2015-02, Vol.6 (1), p.6282-6282, Article 6282

2015

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NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS

The Journal of experimental medicine, 2020-05, Vol.217 (5)

2020

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Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies

Nature communications, 2022-01, Vol.13 (1), p.166-166, Article 166

2022

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TNF and IL-1 Play Essential but Temporally Distinct Roles in Driving Cardiac Inflammation in a Murine Model of Kawasaki Disease

The Journal of immunology (1950), 2019-06, Vol.202 (11), p.3151-3160

2019

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GM-CSF primes cardiac inflammation in a mouse model of Kawasaki disease

The Journal of experimental medicine, 2016-09, Vol.213 (10), p.1983-1998

2016

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Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis

European heart journal, 2018-06, Vol.39 (23), p.2158-2167

2018

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Post-infectious group A streptococcal autoimmune syndromes and the heart

Autoimmunity reviews, 2015-08, Vol.14 (8), p.710-725

2015

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Different cross-presentation pathways in steady-state and inflammatory dendritic cells

Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (48), p.20377-20381

2009

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G-CSF and GM-CSF as therapeutic targets in rheumatoid arthritis

Nature reviews. Rheumatology, 2009-10, Vol.5 (10), p.554-559

2009

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GM-CSF as a therapeutic target in inflammatory diseases

Molecular immunology, 2013-12, Vol.56 (4), p.675-682

2013

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Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis

The Journal of immunology (1950), 2016-12, Vol.197 (11), p.4392-4402

2016

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Mechanistic Target of Rapamycin Inhibition Prevents Coronary Artery Remodeling in a Murine Model of Kawasaki Disease

Arthritis & rheumatology (Hoboken, N.J.), 2023-02, Vol.75 (2), p.305-317

2023

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Interleukin-6 in rheumatoid arthritis - from the laboratory to the bedside

Current pharmaceutical design, 2015-01, Vol.21 (17), p.2187

2015

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GM‐CSF increases cross‐presentation and CD103 expression by mouse CD8+ spleen dendritic cells

European journal of immunology, 2011-09, Vol.41 (9), p.2585-2595

2011

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A key role for G-CSF–induced neutrophil production and trafficking during inflammatory arthritis

Blood, 2008-12, Vol.112 (13), p.5193-5201

2008

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Granulocyte colony-stimulating factor and neutrophils-forgotten mediators of inflammatory disease

Nature clinical practice. Rheumatology, 2006-09, Vol.2 (9), p.500-510

2006

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Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia

Blood, 2007-10, Vol.110 (7), p.2371-2380

2007

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Severe inflammatory arthritis and lymphadenopathy in the absence of TNF

The Journal of clinical investigation, 2001-06, Vol.107 (12), p.1519-1527

2001

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The Pyroptotic Cell Death Effector Gasdermin D Is Activated by Gout-Associated Uric Acid Crystals but Is Dispensable for Cell Death and IL-1β Release

The Journal of immunology (1950), 2019-08, Vol.203 (3), p.736-748

2019

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Critical Role for Granulocyte Colony-Stimulating Factor in Inflammatory Arthritis

Proceedings of the National Academy of Sciences - PNAS, 2004-08, Vol.101 (31), p.11398-11403

2004

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Collagen‐induced arthritis in C57BL/6 (H‐2b) mice: new insights into an important disease model of rheumatoid arthritis

European journal of immunology, 2000-06, Vol.30 (6), p.1568-1575

2000

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Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation

The Journal of experimental medicine, 2001-07, Vol.194 (2), p.189-204

2001

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Cell death in chronic inflammation: breaking the cycle to treat rheumatic disease

Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma

TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS

Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies

TNF and IL-1 Play Essential but Temporally Distinct Roles in Driving Cardiac Inflammation in a Murine Model of Kawasaki Disease

GM-CSF primes cardiac inflammation in a mouse model of Kawasaki disease

Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis

Post-infectious group A streptococcal autoimmune syndromes and the heart

Different cross-presentation pathways in steady-state and inflammatory dendritic cells

G-CSF and GM-CSF as therapeutic targets in rheumatoid arthritis

GM-CSF as a therapeutic target in inflammatory diseases

Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis

Mechanistic Target of Rapamycin Inhibition Prevents Coronary Artery Remodeling in a Murine Model of Kawasaki Disease

Interleukin-6 in rheumatoid arthritis - from the laboratory to the bedside

GM‐CSF increases cross‐presentation and CD103 expression by mouse CD8+ spleen dendritic cells

A key role for G-CSF–induced neutrophil production and trafficking during inflammatory arthritis

Granulocyte colony-stimulating factor and neutrophils-forgotten mediators of inflammatory disease

Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia

Severe inflammatory arthritis and lymphadenopathy in the absence of TNF

The Pyroptotic Cell Death Effector Gasdermin D Is Activated by Gout-Associated Uric Acid Crystals but Is Dispensable for Cell Death and IL-1β Release

Critical Role for Granulocyte Colony-Stimulating Factor in Inflammatory Arthritis

Collagen‐induced arthritis in C57BL/6 (H‐2b) mice: new insights into an important disease model of rheumatoid arthritis

Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation

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