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Transporters and drug-drug interactions: important determinants of drug disposition and effects

Pharmacological reviews, 2013-07, Vol.65 (3), p.944-966

2013

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Thermal effects of Ho:YAG laser lithotripsy during retrograde intrarenal surgery and percutaneous nephrolithotomy in an ex vivo porcine kidney model

World journal of urology, 2020-03, Vol.38 (3), p.753-760

2020

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Genomic distribution and inter-sample variation of non-CpG methylation across human cell types

PLoS genetics, 2011-12, Vol.7 (12), p.e1002389-e1002389

2011

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First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy

ACS chemical biology, 2022-02, Vol.17 (2), p.361-375

2022

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Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development

Genome medicine, 2018-04, Vol.10 (1), p.27-27, Article 27

2018

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Contribution of MATE1 to Renal Secretion of the NMDA Receptor Antagonist Memantine

Molecular pharmaceutics, 2017-09, Vol.14 (9), p.2991-2998

2017

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A comprehensive analysis of 195 DNA methylomes reveals shared and cell-specific features of partially methylated domains

Genome Biology, 2018-09, Vol.19 (1), p.150-150, Article 150

2018

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Role of organic cation transporter OCT2 and multidrug and toxin extrusion proteins MATE1 and MATE2-K for transport and drug interactions of the antiviral lamivudine

Biochemical pharmacology, 2013-09, Vol.86 (6), p.808-815

2013

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Importance of OCT2 and MATE1 for the Cimetidine–Metformin Interaction: Insights from Investigations of Polarized Transport in Single- And Double-Transfected MDCK Cells with a Focus on Perpetrator Disposition

Molecular pharmaceutics, 2018-08, Vol.15 (8), p.3425-3433

2018

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Influence of non-steroidal anti-inflammatory drugs on organic anion transporting polypeptide (OATP) 1B1- and OATP1B3-mediated drug transport

Drug metabolism and disposition, 2011-06, Vol.39 (6), p.1047-1053

2011

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Targeted inhibition of protein synthesis renders cancer cells vulnerable to apoptosis by unfolded protein response

Cell death & disease, 2023-08, Vol.14 (8), p.561-13, Article 561

2023

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The Nonmetabolized β‑Blocker Nadolol Is a Substrate of OCT1, OCT2, MATE1, MATE2-K, and P‑Glycoprotein, but Not of OATP1B1 and OATP1B3

Molecular pharmaceutics, 2016-02, Vol.13 (2), p.512-519

2016

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Molecular Mechanism of Renal Tubular Secretion of the Antimalarial Drug Chloroquine

Antimicrobial Agents and Chemotherapy, 2011-07, Vol.55 (7), p.3091-3098

2011

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Synergistic immunotoxin-paclitaxel combination against lymphoma

Aging (Albany, NY.), 2017-06, Vol.9 (6), p.1471-1472

Müller, Fabian

2017

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Evaluation of high-resolution In Vivo MRI for longitudinal analysis of endochondral fracture healing in mice

PloS one, 2017-03, Vol.12 (3), p.e0174283-e0174283

2017

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Biomarkers for In Vivo Assessment of Transporter Function

Pharmacological reviews, 2018-04, Vol.70 (2), p.246-277

2018

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Identification of a second glycoform of the clinically prevalent O1 antigen from Klebsiella pneumoniae

Proceedings of the National Academy of Sciences - PNAS, 2023-07, Vol.120 (29), p.e2301302120-e2301302120

2023

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Orientation and depth dependent mechanical properties of the porcine cornea: Experiments and parameter identification

Experimental eye research, 2022-11, Vol.224, p.109266-109266, Article 109266

2022

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Protein Kinase Inhibitor H89 Enhances the Activity of Pseudomonas Exotoxin A-Based Immunotoxins

Molecular cancer therapeutics, 2016-05, Vol.15 (5), p.1053-1062

2016

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Paclitaxel synergizes with exposure time adjusted CD22-targeting immunotoxins against B-cell malignancies

Oncotarget, 2017-05, Vol.8 (19), p.30644-30655

2017

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The EMT transcription factor ZEB1 blocks osteoblastic differentiation in bone development and osteosarcoma

The Journal of pathology, 2021-06, Vol.254 (2), p.199-211

2021

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Emtricitabine is a substrate of MATE1 but not of OCT1, OCT2, P-gp, BCRP or MRP2 transporters

Xenobiotica, 2017-01, Vol.47 (1), p.77-85

2017

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CAR T-Cell Therapy in Autoimmune Disease

The New England journal of medicine, 2024-05, Vol.390 (17), p.1628-1632

2024

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Clinical relevance of drug efflux pumps in the gut

Current opinion in pharmacology, 2013-12, Vol.13 (6), p.847-852

2013

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Multifaceted role for p53 in pancreatic cancer suppression

Proceedings of the National Academy of Sciences - PNAS, 2023-03, Vol.120 (10), p.e2211937120-e2211937120

2023

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Transporters and drug-drug interactions: important determinants of drug disposition and effects

Thermal effects of Ho:YAG laser lithotripsy during retrograde intrarenal surgery and percutaneous nephrolithotomy in an ex vivo porcine kidney model

Genomic distribution and inter-sample variation of non-CpG methylation across human cell types

First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy

Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development

Contribution of MATE1 to Renal Secretion of the NMDA Receptor Antagonist Memantine

A comprehensive analysis of 195 DNA methylomes reveals shared and cell-specific features of partially methylated domains

Role of organic cation transporter OCT2 and multidrug and toxin extrusion proteins MATE1 and MATE2-K for transport and drug interactions of the antiviral lamivudine

Importance of OCT2 and MATE1 for the Cimetidine–Metformin Interaction: Insights from Investigations of Polarized Transport in Single- And Double-Transfected MDCK Cells with a Focus on Perpetrator Disposition

Influence of non-steroidal anti-inflammatory drugs on organic anion transporting polypeptide (OATP) 1B1- and OATP1B3-mediated drug transport

Targeted inhibition of protein synthesis renders cancer cells vulnerable to apoptosis by unfolded protein response

The Nonmetabolized β‑Blocker Nadolol Is a Substrate of OCT1, OCT2, MATE1, MATE2-K, and P‑Glycoprotein, but Not of OATP1B1 and OATP1B3

Molecular Mechanism of Renal Tubular Secretion of the Antimalarial Drug Chloroquine

Synergistic immunotoxin-paclitaxel combination against lymphoma

Evaluation of high-resolution In Vivo MRI for longitudinal analysis of endochondral fracture healing in mice

Biomarkers for In Vivo Assessment of Transporter Function

Identification of a second glycoform of the clinically prevalent O1 antigen from Klebsiella pneumoniae

Orientation and depth dependent mechanical properties of the porcine cornea: Experiments and parameter identification

Protein Kinase Inhibitor H89 Enhances the Activity of Pseudomonas Exotoxin A-Based Immunotoxins

Paclitaxel synergizes with exposure time adjusted CD22-targeting immunotoxins against B-cell malignancies

The EMT transcription factor ZEB1 blocks osteoblastic differentiation in bone development and osteosarcoma

Emtricitabine is a substrate of MATE1 but not of OCT1, OCT2, P-gp, BCRP or MRP2 transporters

CAR T-Cell Therapy in Autoimmune Disease

Clinical relevance of drug efflux pumps in the gut

Multifaceted role for p53 in pancreatic cancer suppression

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