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Identification and characterization of Cardiac Glycosides as senolytic compounds

Nature communications, 2019-10, Vol.10 (1), p.4731-4731, Article 4731

2019

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5-HT2 receptor binding, functional activity and selectivity in N-benzyltryptamines

PloS one, 2019-01, Vol.14 (1), p.e0209804-e0209804

2019

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Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy

EBioMedicine, 2019-07, Vol.45, p.588-605

2019

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Lentiviral Vectors for the Treatment and Prevention of Cystic Fibrosis Lung Disease

Genes, 2019-03, Vol.10 (3), p.218

2019

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Gamma-decanolactone: Preliminary evaluation as potential antiparkinsonian drug

European journal of pharmacology, 2021-09, Vol.906, p.174276, Article 174276

2021

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Discovery of V‑0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide‑1 Receptor toward Oral Treatment for “Diabesity”

Journal of medicinal chemistry, 2022-04, Vol.65 (7), p.5449-5461

2022

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The PI3Kδ Inhibitor Idelalisib Diminishes Platelet Function and Shows Antithrombotic Potential

International journal of molecular sciences, 2021-03, Vol.22 (7), p.3304

2021

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Exploring the Effect of Halogenation in a Series of Potent and Selective A 2B Adenosine Receptor Antagonists

Journal of medicinal chemistry, 2023-01, Vol.66 (1), p.890-912

2023

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Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model

European journal of medicinal chemistry, 2012, Vol.47 (1), p.175-185

2012

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Reelin influences the expression and function of dopamine D2 and serotonin 5-HT2A receptors: A comparative study

Neuroscience, 2015-04, Vol.290, p.165-174

2015

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Cytocompatibility and P‑glycoprotein Inhibition of Block Copolymers: Structure–Activity Relationship

Molecular pharmaceutics, 2013-08, Vol.10 (8), p.3232-3241

2013

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Chitosan–hyaluronic acid nanoparticles loaded with heparin for the treatment of asthma

International journal of pharmaceutics, 2009-11, Vol.381 (2), p.122-129

2009

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Synthesis and binding affinity of potential atypical antipsychotics with the tetrahydroquinazolinone motif

Bioorganic & medicinal chemistry letters, 2009-11, Vol.19 (21), p.6059-6062

2009

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Synthesis, pharmacological and structural studies of 5-substituted-3-(1-arylmethyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as multi-target ligands of aminergic GPCRs

European journal of medicinal chemistry, 2019-10, Vol.180, p.673-689

2019

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Nitrogen-Walk Approach to Explore Bioisosteric Replacements in a Series of Potent A 2B Adenosine Receptor Antagonists

Journal of medicinal chemistry, 2020-07, Vol.63 (14), p.7721-7739

2020

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Discovery of novel arylpiperazine-based DA/5-HT modulators as potential antipsychotic agents – Design, synthesis, structural studies and pharmacological profiling

European journal of medicinal chemistry, 2023-04, Vol.252, p.115285-115285, Article 115285

2023

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Doxorubicin-loaded micelles of reverse poly(butylene oxide)–poly(ethylene oxide)–poly(butylene oxide) block copolymers as efficient “active” chemotherapeutic agents

International journal of pharmaceutics, 2013-03, Vol.445 (1-2), p.47-57

2013

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Effect of Nitrogen Atom Substitution in A 3 Adenosine Receptor Binding: N-(4,6-Diarylpyridin-2-yl)acetamides as Potent and Selective Antagonists

Journal of medicinal chemistry, 2017-09, Vol.60 (17), p.7502-7511

2017

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A Positive Allosteric Modulator of the Serotonin 5-HT 2C Receptor for Obesity

Journal of medicinal chemistry, 2017-12, Vol.60 (23), p.9575-9584

2017

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A Potential Nanomedicine Consisting of Heparin-Loaded Polysaccharide Nanocarriers for the Treatment of Asthma

Macromolecular bioscience, 2012-02, Vol.12 (2), p.176-183

2012

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Serotonin 2A receptor disulfide bridge integrity is crucial for ligand binding to different signalling states but not for its homodimerization

European journal of pharmacology, 2017-11, Vol.815, p.138-146

2017

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Docking Screens for Dual Inhibitors of Disparate Drug Targets for Parkinson’s Disease

Journal of medicinal chemistry, 2018-06, Vol.61 (12), p.5269-5278

2018

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Study of the mechanism of the relaxant action of (+)‐glaucine in rat vas deferens

British journal of pharmacology, 1993-11, Vol.110 (3), p.943-948

1993

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Multiple conformations of native and recombinant human 5-hydroxytryptamine(2a) receptors are labeled by agonists and discriminated by antagonists

Molecular pharmacology, 2001-10, Vol.60 (4), p.690-699

2001

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Identification and characterization of Cardiac Glycosides as senolytic compounds

5-HT2 receptor binding, functional activity and selectivity in N-benzyltryptamines

Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy

Lentiviral Vectors for the Treatment and Prevention of Cystic Fibrosis Lung Disease

Gamma-decanolactone: Preliminary evaluation as potential antiparkinsonian drug

Discovery of V‑0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide‑1 Receptor toward Oral Treatment for “Diabesity”

The PI3Kδ Inhibitor Idelalisib Diminishes Platelet Function and Shows Antithrombotic Potential

Exploring the Effect of Halogenation in a Series of Potent and Selective A 2B Adenosine Receptor Antagonists

Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model

Reelin influences the expression and function of dopamine D2 and serotonin 5-HT2A receptors: A comparative study

Cytocompatibility and P‑glycoprotein Inhibition of Block Copolymers: Structure–Activity Relationship

Chitosan–hyaluronic acid nanoparticles loaded with heparin for the treatment of asthma

Synthesis and binding affinity of potential atypical antipsychotics with the tetrahydroquinazolinone motif

Synthesis, pharmacological and structural studies of 5-substituted-3-(1-arylmethyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as multi-target ligands of aminergic GPCRs

Nitrogen-Walk Approach to Explore Bioisosteric Replacements in a Series of Potent A 2B Adenosine Receptor Antagonists

Discovery of novel arylpiperazine-based DA/5-HT modulators as potential antipsychotic agents – Design, synthesis, structural studies and pharmacological profiling

Doxorubicin-loaded micelles of reverse poly(butylene oxide)–poly(ethylene oxide)–poly(butylene oxide) block copolymers as efficient “active” chemotherapeutic agents

3,4-Dihydropyrimidin-2(1 H )-ones as Antagonists of the Human A 2B Adenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific Recognition

Effect of Nitrogen Atom Substitution in A 3 Adenosine Receptor Binding: N-(4,6-Diarylpyridin-2-yl)acetamides as Potent and Selective Antagonists

A Positive Allosteric Modulator of the Serotonin 5-HT 2C Receptor for Obesity

A Potential Nanomedicine Consisting of Heparin-Loaded Polysaccharide Nanocarriers for the Treatment of Asthma

Serotonin 2A receptor disulfide bridge integrity is crucial for ligand binding to different signalling states but not for its homodimerization

Docking Screens for Dual Inhibitors of Disparate Drug Targets for Parkinson’s Disease

Study of the mechanism of the relaxant action of (+)‐glaucine in rat vas deferens

Multiple conformations of native and recombinant human 5-hydroxytryptamine(2a) receptors are labeled by agonists and discriminated by antagonists

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