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Regulation of intestinal permeability: The role of proteases

World journal of gastroenterology : WJG, 2017-03, Vol.23 (12), p.2106-2123

2017

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Newly developed serine protease inhibitors decrease visceral hypersensitivity in a post‐inflammatory rat model for irritable bowel syndrome

British journal of pharmacology, 2018-09, Vol.175 (17), p.3516-3533

2018

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Selective inhibition of carboxypeptidase U may reduce microvascular thrombosis in rat experimental stroke

Journal of thrombosis and haemostasis, 2020-12, Vol.18 (12), p.3325-3335

2020

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Visceral hypersensitivity in inflammatory bowel diseases and irritable bowel syndrome: The role of proteases

World journal of gastroenterology : WJG, 2016-12, Vol.22 (47), p.10275-10286

2016

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Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)

Journal of medicinal chemistry, 2014-04, Vol.57 (7), p.3053-3074

2014

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Translational research on prolyl oligopeptidase inhibitors: the long road ahead

Expert opinion on therapeutic patents, 2011-07, Vol.21 (7), p.977-981

Lambeir, Anne-Marie

2011

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The potential of carboxypeptidase M as a therapeutic target in cancer

Expert opinion on therapeutic targets, 2013-03, Vol.17 (3), p.265-279

2013

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DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages

Life science alliance, 2019-02, Vol.2 (1), p.e201900313

2019

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Importance of biofilm formation and dipeptidyl peptidase IV for the pathogenicity of clinical Porphyromonas gingivalis isolates

Pathogens and disease, 2014-04, Vol.70 (3), p.408-413

2014

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C-terminal clipping of chemokine CCL1/I-309 enhances CCR8-mediated intracellular calcium release and anti-apoptotic activity

PloS one, 2012-03, Vol.7 (3), p.e34199-e34199

2012

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A novel serine protease inhibitor as potential treatment for dry eye syndrome and ocular inflammation

Scientific reports, 2020-10, Vol.10 (1), p.17268-17268, Article 17268

2020

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Prolyl carboxypeptidase purified from human placenta: its characterization and identification as an apelin-cleaving enzyme

Biochimica et biophysica acta, 2016-11, Vol.1864 (11), p.1481-1488

2016

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Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV

Critical reviews in clinical laboratory sciences, 2003-01, Vol.40 (3), p.209-294

2003

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Method comparison of dipeptidyl peptidase IV activity assays and their application in biological samples containing reversible inhibitors

Clinica chimica acta, 2012-02, Vol.413 (3), p.456-462

2012

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In vivo profiling of DPP4 inhibitors reveals alterations in collagen metabolism and accumulation of an amyloid peptide in rat plasma

Biochemical pharmacology, 2009-01, Vol.77 (2), p.228-237

2009

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Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7)

Biochemical journal, 2005-03, Vol.386 (Pt 2), p.315-324

2005

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Prolyl endopeptidase is involved in the degradation of neural cell adhesion molecules in vitro

Journal of cell science, 2016-10, Vol.129 (20), p.3792-3802

2016

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Optimization and validation of an existing, surgical and robust dry eye rat model for the evaluation of therapeutic compounds

Experimental eye research, 2016-05, Vol.146, p.172-178

2016

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Suggested functions for prolyl oligopeptidase: A puzzling paradox

Clinica chimica acta, 2007-02, Vol.377 (1-2), p.50-61

2007

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Prolyl oligopeptidase stimulates the aggregation of α-synuclein

Peptides (New York, N.Y. : 1980), 2008-09, Vol.29 (9), p.1472-1478

2008

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Validation of a specific prolylcarboxypeptidase activity assay and its suitability for plasma and serum measurements

Analytical biochemistry, 2013-12, Vol.443 (2), p.232-239

2013

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Small, Potent, and Selective Diaryl Phosphonate Inhibitors for Urokinase-Type Plasminogen Activator with In Vivo Antimetastatic Properties

Journal of medicinal chemistry, 2007-12, Vol.50 (26), p.6638-6646

2007

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Dipeptidyl peptidase 9 (DPP9) from bovine testes: Identification and characterization as the short form by mass spectrometry

Biochimica et biophysica acta, 2010-04, Vol.1804 (4), p.781-788

2010

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In situ prolyl oligopeptidase activity assay in neural cell cultures

Journal of neuroscience methods, 2012-02, Vol.204 (1), p.104-110

2012

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Enzyme Activity and Immunohistochemical Localization of Dipeptidyl Peptidase 8 and 9 in Male Reproductive Tissues

The journal of histochemistry and cytochemistry, 2009-06, Vol.57 (6), p.531-541

2009

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Regulation of intestinal permeability: The role of proteases

Newly developed serine protease inhibitors decrease visceral hypersensitivity in a post‐inflammatory rat model for irritable bowel syndrome

Selective inhibition of carboxypeptidase U may reduce microvascular thrombosis in rat experimental stroke

Visceral hypersensitivity in inflammatory bowel diseases and irritable bowel syndrome: The role of proteases

Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)

Translational research on prolyl oligopeptidase inhibitors: the long road ahead

The potential of carboxypeptidase M as a therapeutic target in cancer

DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages

Importance of biofilm formation and dipeptidyl peptidase IV for the pathogenicity of clinical Porphyromonas gingivalis isolates

C-terminal clipping of chemokine CCL1/I-309 enhances CCR8-mediated intracellular calcium release and anti-apoptotic activity

A novel serine protease inhibitor as potential treatment for dry eye syndrome and ocular inflammation

Prolyl carboxypeptidase purified from human placenta: its characterization and identification as an apelin-cleaving enzyme

Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV

Method comparison of dipeptidyl peptidase IV activity assays and their application in biological samples containing reversible inhibitors

In vivo profiling of DPP4 inhibitors reveals alterations in collagen metabolism and accumulation of an amyloid peptide in rat plasma

Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7)

Prolyl endopeptidase is involved in the degradation of neural cell adhesion molecules in vitro

Optimization and validation of an existing, surgical and robust dry eye rat model for the evaluation of therapeutic compounds

Suggested functions for prolyl oligopeptidase: A puzzling paradox

Prolyl oligopeptidase stimulates the aggregation of α-synuclein

Validation of a specific prolylcarboxypeptidase activity assay and its suitability for plasma and serum measurements

Small, Potent, and Selective Diaryl Phosphonate Inhibitors for Urokinase-Type Plasminogen Activator with In Vivo Antimetastatic Properties

Dipeptidyl peptidase 9 (DPP9) from bovine testes: Identification and characterization as the short form by mass spectrometry

In situ prolyl oligopeptidase activity assay in neural cell cultures

Enzyme Activity and Immunohistochemical Localization of Dipeptidyl Peptidase 8 and 9 in Male Reproductive Tissues

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