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Acylation Cycle Regulates Localization and Activity of Palmitoylated Ras Isoforms

Science (American Association for the Advancement of Science), 2005-03, Vol.307 (5716), p.1746-1752

2005

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Drug research: from the idea to the product

International journal of clinical pharmacology and therapeutics, 1997-12, Vol.35 (12), p.541

Kuhlmann, J

1997

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Synthesis of palmitoylated Ras-peptides and -proteins

Methods (San Diego, Calif.), 2006-10, Vol.40 (2), p.151-165

2006

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Synthesis of Functional Ras Lipoproteins and Fluorescent Derivatives

Journal of the American Chemical Society, 2001-02, Vol.123 (6), p.1023-1035

2001

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Correlation between insulin resistance and intramyocellular lipid levels in rats

Magnetic resonance in medicine, 2005-06, Vol.53 (6), p.1275-1282

2005

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Optimizing the science of drug development: opportunities for better candidate selection and accelerated evaluation in humans

European journal of pharmaceutical sciences, 2000, Vol.10 (4), p.iv-xiv

2000

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The Cholesterol Membrane Anchor of the Hedgehog Protein Confers Stable Membrane Association to Lipid-Modified Proteins

Proceedings of the National Academy of Sciences - PNAS, 2004-06, Vol.101 (23), p.8531-8536

2004

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Dissecting the Interactions between NTF2, RanGDP, and the Nucleoporin XFXFG Repeats

The Journal of biological chemistry, 2000-02, Vol.275 (8), p.5874-5879

2000

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Bioorganic synthesis of lipid-modified proteins for the study of signal transduction

Nature (London), 2000-01, Vol.403 (6766), p.223-226

2000

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Synthesis and Application of Fluorescence-Labeled Ras-Proteins for Live-Cell Imaging

Angewandte Chemie (International ed.), 2004-05, Vol.43 (20), p.2711-2714

2004

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The applications of biomarkers in early clinical drug development to improve decision-making processes

Ernst Schering Research Foundation workshop, 2007 (59), p.29

Kuhlmann, J

2007

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Associations of B- and C-Raf with cholesterol, phosphatidylserine, and lipid second messengers: preferential binding of Raf to artificial lipid rafts

The Journal of biological chemistry, 2002-07, Vol.277 (27), p.24090-24102

2002

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Evaluation of Time Dependence and Interindividual Differences in Benzo[a]pyrene-Mediated CYP1A1 Induction and Genotoxicity in Porcine Urinary Bladder Cell Cultures

Journal of Toxicology and Environmental Health, Part A, 2008-01, Vol.71 (13-14), p.969-975

2008

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The adenomatous polyposis coli-protein (APC) interacts with the protein tyrosine phosphatase PTP-BL via an alternatively spliced PDZ domain

Oncogene, 2000-08, Vol.19 (34), p.3894-3901

2000

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Hands and feet of prosimians primates. Attempts of morphologic characterization

Morphologie, 2008-08, Vol.92 (297), p.68-77

Kuhlmann, J N

2008

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The first ray of the hand and the foot in the primates (II). Functional anatomy

Morphologie, 2008-08, Vol.92 (297), p.55-67

Kuhlmann, J-N

2008

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Synthesis and Biological Activity of Photoactivatable N-Ras Peptides and Proteins

Journal of the American Chemical Society, 2003-10, Vol.125 (42), p.12749-12758

2003

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Synthesis and Application of Fluorescent Ras Proteins for Live-Cell Imaging

Chembiochem : a European journal of chemical biology, 2005-01, Vol.6 (1), p.86-94

2005

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Miniaturization of Primary Porcine Urinary Bladder Epithelial Cell Cultures and Application for Gene Expression Studies after Exposure to Benzo[a]Pyrene

Journal of Toxicology and Environmental Health, Part A, 2008-01, Vol.71 (13-14), p.915-922

2008

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Pharmacokinetics of the controlled-release nisoldipine coat-core tablet formulation

International journal of clinical pharmacology and therapeutics, 1997-08, Vol.35 (8), p.341

1997

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Development and Biological Evaluation of Acyl Protein Thioesterase 1 (APT1) Inhibitors

Angewandte Chemie (International ed.), 2005-08, Vol.44 (31), p.4975-4980

2005

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The effect of benzo( a)pyrene on porcine urinary bladder epithelial cells analyzed for the expression of selected genes and cellular toxicological endpoints

Toxicology (Amsterdam), 2005-02, Vol.207 (2), p.255-269

2005

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Muscle type-specific fatty acid metabolism in insulin resistance: an integrated in vivo study in Zucker diabetic fatty rats

American journal of physiology: endocrinology and metabolism, 2006-05, Vol.290 (5), p.E989-E997

2006

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Hands and feet of Simian primates: an attempt at morphological characterization

Morphologie, 2005-06, Vol.89 (285), p.102

Kuhlmann, J N

2005

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Rat Adjuvant Arthritis: Imaging with Technetium-99m-Anti-CD4 Fab' Fragments

The Journal of nuclear medicine (1978), 1995-12, Vol.36 (12), p.2268-2275

1995

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Acylation Cycle Regulates Localization and Activity of Palmitoylated Ras Isoforms

Drug research: from the idea to the product

Synthesis of palmitoylated Ras-peptides and -proteins

Synthesis of Functional Ras Lipoproteins and Fluorescent Derivatives

Correlation between insulin resistance and intramyocellular lipid levels in rats

Optimizing the science of drug development: opportunities for better candidate selection and accelerated evaluation in humans

The Cholesterol Membrane Anchor of the Hedgehog Protein Confers Stable Membrane Association to Lipid-Modified Proteins

Dissecting the Interactions between NTF2, RanGDP, and the Nucleoporin XFXFG Repeats

Bioorganic synthesis of lipid-modified proteins for the study of signal transduction

Synthesis and Application of Fluorescence-Labeled Ras-Proteins for Live-Cell Imaging

The applications of biomarkers in early clinical drug development to improve decision-making processes

Associations of B- and C-Raf with cholesterol, phosphatidylserine, and lipid second messengers: preferential binding of Raf to artificial lipid rafts

Evaluation of Time Dependence and Interindividual Differences in Benzo[a]pyrene-Mediated CYP1A1 Induction and Genotoxicity in Porcine Urinary Bladder Cell Cultures

The adenomatous polyposis coli-protein (APC) interacts with the protein tyrosine phosphatase PTP-BL via an alternatively spliced PDZ domain

Hands and feet of prosimians primates. Attempts of morphologic characterization

The first ray of the hand and the foot in the primates (II). Functional anatomy

Synthesis and Biological Activity of Photoactivatable N-Ras Peptides and Proteins

Synthesis and Application of Fluorescent Ras Proteins for Live-Cell Imaging

Miniaturization of Primary Porcine Urinary Bladder Epithelial Cell Cultures and Application for Gene Expression Studies after Exposure to Benzo[a]Pyrene

Pharmacokinetics of the controlled-release nisoldipine coat-core tablet formulation

Development and Biological Evaluation of Acyl Protein Thioesterase 1 (APT1) Inhibitors

The effect of benzo( a)pyrene on porcine urinary bladder epithelial cells analyzed for the expression of selected genes and cellular toxicological endpoints

Muscle type-specific fatty acid metabolism in insulin resistance: an integrated in vivo study in Zucker diabetic fatty rats

Hands and feet of Simian primates: an attempt at morphological characterization

Rat Adjuvant Arthritis: Imaging with Technetium-99m-Anti-CD4 Fab' Fragments

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