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Bioinorganic Chemistry of Alzheimer’s Disease

Chemical reviews, 2012-10, Vol.112 (10), p.5193-5239

Kepp, Kasper P

2012

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Alzheimer's disease due to loss of function: A new synthesis of the available data

Progress in neurobiology, 2016-08, Vol.143, p.36-60

Kepp, Kasper P

2016

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Towards a “Golden Standard” for computing globin stability: Stability and structure sensitivity of myoglobin mutants

Biochimica et biophysica acta, 2015-10, Vol.1854 (10), p.1239-1248

Kepp, Kasper P.

2015

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Superoxide dismutase 1 is positively selected to minimize protein aggregation in great apes

Cellular and molecular life sciences : CMLS, 2017-08, Vol.74 (16), p.3023-3037

2017

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Unfolding simulations of holomyoglobin from four mammals: identification of intermediates and β-sheet formation from partially unfolded states

PloS one, 2013-12, Vol.8 (12), p.e80308-e80308

2013

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Positively selected sites in cetacean myoglobins contribute to protein stability

PLoS computational biology, 2013-03, Vol.9 (3), p.e1002929-e1002929

2013

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Common mechanism of thermostability in small α‐ and β‐proteins studied by molecular dynamics

Proteins, structure, function, and bioinformatics, 2020-09, Vol.88 (9), p.1233-1250

2020

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Evolution of endemism on a young tropical mountain

Nature (London), 2015-08, Vol.524 (7565), p.347-350

2015

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Tracking evolution of myoglobin stability in cetaceans using experimentally calibrated computational methods that account for generic protein relaxation

Biochimica et biophysica acta, 2016-07, Vol.1864 (7), p.825-834

2016

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Modeling the Aggregation Propensity and Toxicity of Amyloid-β Variants

Journal of Alzheimer's disease, 2015-01, Vol.47 (1), p.215-229

2015

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Bridging the gap between chemistry, physiology, and evolution: Quantifying the functionality of sperm whale myoglobin mutants

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2012, Vol.161 (1), p.9-17

2012

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Aerobic dive limits of seals with mutant myoglobin using combined thermochemical and physiological data

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2013-01, Vol.164 (1), p.119-128

2013

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Summary of major conclusions from the 4th IWGT, San Francisco, 9–10 September, 2005

Mutation research, 2007-02, Vol.627 (1), p.5-9

2007

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Summary of major conclusions from the 5th IWGT, Basel, Switzerland, 17–19 August 2009

Mutation research, 2011-08, Vol.723 (2), p.73-76

2011

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Human biological relevance and the use of threshold-arguments in regulatory genotoxicity assessment: experience with pharmaceuticals

Mutation research, 2000-01, Vol.464 (1), p.19-34

2000

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Experimentally calibrated computational chemistry of tryptophan hydroxylase: trans influence, hydrogen-bonding, and 18-electron rule govern O2-activation

Journal of inorganic biochemistry, 2010-02, Vol.104 (2), p.136-145

2010

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Relevance and follow-up of positive results in in vitro genetic toxicity assays: An ILSI-HESI initiative

Mutation research, 2007-10, Vol.633 (2), p.67-79

2007

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The International Workshops on Genotoxicity Testing (IWGT): History and achievements

Mutation research, 2007-02, Vol.627 (1), p.1-4

2007

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The application of the micronucleus test in Chinese hamster V79 cells to detect drug-induced photogenotoxicity

Mutation research, 1999-09, Vol.445 (1), p.55-71

1999

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Follow-up testing of rodent carcinogens not positive in the standard genotoxicity testing battery: IWGT workgroup report

Mutation research, 2007-02, Vol.627 (1), p.106-116

2007

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Recommended lists of genotoxic and non-genotoxic chemicals for assessment of the performance of new or improved genotoxicity tests: A follow-up to an ECVAM workshop

Mutation research, 2008-05, Vol.653 (1), p.99-108

2008

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A critical appraisal of the sensitivity of in vivo genotoxicity assays in detecting human carcinogens

Mutagenesis, 2018-04, Vol.33 (2), p.179-193

2018

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Use of the photo-micronucleus assay in Chinese hamster V79 cells to study photochemical genotoxicity

Mutation research, 2002-08, Vol.519 (1-2), p.49-66

2002

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Strategy for genotoxicity testing and stratification of genotoxicity test results—report on initial activities of the IWGT Expert Group

Mutation research, 2003-10, Vol.540 (2), p.177-181

2003

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Bioinorganic Chemistry of Alzheimer’s Disease

Alzheimer's disease due to loss of function: A new synthesis of the available data

Towards a “Golden Standard” for computing globin stability: Stability and structure sensitivity of myoglobin mutants

Superoxide dismutase 1 is positively selected to minimize protein aggregation in great apes

Unfolding simulations of holomyoglobin from four mammals: identification of intermediates and β-sheet formation from partially unfolded states

Positively selected sites in cetacean myoglobins contribute to protein stability

Common mechanism of thermostability in small α‐ and β‐proteins studied by molecular dynamics

Evolution of endemism on a young tropical mountain

Tracking evolution of myoglobin stability in cetaceans using experimentally calibrated computational methods that account for generic protein relaxation

Modeling the Aggregation Propensity and Toxicity of Amyloid-β Variants

How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop

Bridging the gap between chemistry, physiology, and evolution: Quantifying the functionality of sperm whale myoglobin mutants

Aerobic dive limits of seals with mutant myoglobin using combined thermochemical and physiological data

Summary of major conclusions from the 4th IWGT, San Francisco, 9–10 September, 2005

Summary of major conclusions from the 5th IWGT, Basel, Switzerland, 17–19 August 2009

Human biological relevance and the use of threshold-arguments in regulatory genotoxicity assessment: experience with pharmaceuticals

Experimentally calibrated computational chemistry of tryptophan hydroxylase: trans influence, hydrogen-bonding, and 18-electron rule govern O2-activation

Relevance and follow-up of positive results in in vitro genetic toxicity assays: An ILSI-HESI initiative

The International Workshops on Genotoxicity Testing (IWGT): History and achievements

The application of the micronucleus test in Chinese hamster V79 cells to detect drug-induced photogenotoxicity

Follow-up testing of rodent carcinogens not positive in the standard genotoxicity testing battery: IWGT workgroup report

Recommended lists of genotoxic and non-genotoxic chemicals for assessment of the performance of new or improved genotoxicity tests: A follow-up to an ECVAM workshop

A critical appraisal of the sensitivity of in vivo genotoxicity assays in detecting human carcinogens

Use of the photo-micronucleus assay in Chinese hamster V79 cells to study photochemical genotoxicity

Strategy for genotoxicity testing and stratification of genotoxicity test results—report on initial activities of the IWGT Expert Group

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