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Potent antileukemic activity of curaxin CBL0137 against MLL‐rearranged leukemia

International journal of cancer, 2020-04, Vol.146 (7), p.1902-1916

2020

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Effective targeting of the P53-MDM2 axis in preclinical models of infant MLL-rearranged acute lymphoblastic leukemia

Clinical cancer research, 2015-03, Vol.21 (6), p.1395-1405

2015

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Connective tissue growth factor is expressed in bone marrow stromal cells and promotes interleukin-7-dependent B lymphopoiesis

Haematologica (Roma), 2014-07, Vol.99 (7), p.1149-1156

2014

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Silencing of TESTIN by dense biallelic promoter methylation is the most common molecular event in childhood acute lymphoblastic leukaemia

Molecular cancer, 2010-06, Vol.9 (1), p.163-163

2010

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Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin

British journal of cancer, 2021-07, Vol.125 (1), p.55-64

2021

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The bone marrow microenvironment of pre-B acute lymphoblastic leukemia at single-cell resolution

Scientific reports, 2020-11, Vol.10 (1), p.19173-19173, Article 19173

2020

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Validation of a mouse xenograft model system for gene expression analysis of human acute lymphoblastic leukaemia

BMC genomics, 2010-04, Vol.11 (1), p.256-256, Article 256

2010

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Divergent mechanisms of glucocorticoid resistance in experimental models of pediatric acute lymphoblastic leukemia

Cancer research (Chicago, Ill.), 2007-05, Vol.67 (9), p.4482-4490

2007

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Heterogeneity in mechanisms of emergent resistance in pediatric T-cell acute lymphoblastic leukemia

Oncotarget, 2016-09, Vol.7 (37), p.58728-58742

2016

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Macrophage-Derived Nitric Oxide Regulates T Cell Activation via Reversible Disruption of the Jak3/STAT5 Signaling Pathway

The Journal of immunology (1950), 1998-06, Vol.160 (12), p.5729-5734

1998

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Transcriptional regulation of FHL1 by TLX1/HOX11 is dosage, cell-type and promoter context-dependent

Biochemical and biophysical research communications, 2008-03, Vol.367 (3), p.707-713

2008

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Overexpression of stem cell associated ALDH1A1 , a target of the leukemogenic transcription factor TLX1/HOX11, inhibits lymphopoiesis and promotes myelopoiesis in murine hematopoietic progenitors

Leukemia research, 2008-06, Vol.32 (6), p.873-883

2008

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Cell lines from MYCN transgenic murine tumours reflect the molecular and biological characteristics of human neuroblastoma

European journal of cancer (1990), 2007-06, Vol.43 (9), p.1467-1475

2007

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TLX1/HOX11 transcription factor inhibits differentiation and promotes a non‐haemopoietic phenotype in murine bone marrow cells

British journal of haematology, 2007-07, Vol.138 (1), p.54-67

2007

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A xenograft model of infant leukaemia reveals a complex MLL translocation

British journal of haematology, 2008-03, Vol.140 (6), p.716-719

2008

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Enforced expression of HOX11 is associated with an immature phenotype in J2E erythroid cells

British journal of haematology, 2002-09, Vol.118 (3), p.909-917

2002

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Regions syntenic to human 17q are gained in mouse and rat neuroblastoma

Genes chromosomes & cancer, 2004-06, Vol.40 (2), p.158-163

2004

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Multiple negative elements contribute to repression of the HOX11 proto-oncogene

Oncogene, 1998-10, Vol.17 (14), p.1787-1795

1998

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Medulloblastoma/primitive neuroectodermal tumour studied as a Matrigel enhanced subcutaneous xenograft model

Journal of clinical neuroscience, 2001-03, Vol.8 (2), p.151-156

2001

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Incomplete Tolerance to MHC Antigens in Irradiation Chimeras: Implications for MHC Restriction and Self Tolerance

Immunological reviews, 1981-01, Vol.58 (1), p.25-36

1981

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A single genetic element in H-2K affects mouse T-cell antiviral function in poxvirus infection

The Journal of experimental medicine, 1976-02, Vol.143 (2), p.450-455

1976

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Cytotoxic T-cell responses show more restricted specificity for self than for non-self H-2D-coded antigens

The Journal of experimental medicine, 1978-06, Vol.147 (6), p.1661-1670

1978

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In vitro primary induction of cytotoxic T cells against virus-infected syngeneic cells

Journal of immunological methods, 1977, Vol.16 (1), p.73-89

1977

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Potent antileukemic activity of curaxin CBL0137 against MLL‐rearranged leukemia

Effective targeting of the P53-MDM2 axis in preclinical models of infant MLL-rearranged acute lymphoblastic leukemia

Connective tissue growth factor is expressed in bone marrow stromal cells and promotes interleukin-7-dependent B lymphopoiesis

Silencing of TESTIN by dense biallelic promoter methylation is the most common molecular event in childhood acute lymphoblastic leukaemia

Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin

The bone marrow microenvironment of pre-B acute lymphoblastic leukemia at single-cell resolution

Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia

Validation of a mouse xenograft model system for gene expression analysis of human acute lymphoblastic leukaemia

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

Divergent mechanisms of glucocorticoid resistance in experimental models of pediatric acute lymphoblastic leukemia

Heterogeneity in mechanisms of emergent resistance in pediatric T-cell acute lymphoblastic leukemia

Macrophage-Derived Nitric Oxide Regulates T Cell Activation via Reversible Disruption of the Jak3/STAT5 Signaling Pathway

Transcriptional regulation of FHL1 by TLX1/HOX11 is dosage, cell-type and promoter context-dependent

Overexpression of stem cell associated ALDH1A1 , a target of the leukemogenic transcription factor TLX1/HOX11, inhibits lymphopoiesis and promotes myelopoiesis in murine hematopoietic progenitors

Cell lines from MYCN transgenic murine tumours reflect the molecular and biological characteristics of human neuroblastoma

TLX1/HOX11 transcription factor inhibits differentiation and promotes a non‐haemopoietic phenotype in murine bone marrow cells

A xenograft model of infant leukaemia reveals a complex MLL translocation

Enforced expression of HOX11 is associated with an immature phenotype in J2E erythroid cells

Regions syntenic to human 17q are gained in mouse and rat neuroblastoma

Multiple negative elements contribute to repression of the HOX11 proto-oncogene

Medulloblastoma/primitive neuroectodermal tumour studied as a Matrigel enhanced subcutaneous xenograft model

Incomplete Tolerance to MHC Antigens in Irradiation Chimeras: Implications for MHC Restriction and Self Tolerance

A single genetic element in H-2K affects mouse T-cell antiviral function in poxvirus infection

Cytotoxic T-cell responses show more restricted specificity for self than for non-self H-2D-coded antigens

In vitro primary induction of cytotoxic T cells against virus-infected syngeneic cells

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