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Harnessing CXCR4 antagonists in stem cell mobilization, HIV infection, ischemic diseases, and oncology

Medicinal research reviews, 2018-07, Vol.38 (4), p.1188-1234

2018

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Optimization of Ligand and Lipophilic Efficiency To Identify an in Vivo Active Furano-Pyrimidine Aurora Kinase Inhibitor

Journal of medicinal chemistry, 2013-07, Vol.56 (13), p.5247-5260

2013

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Discovery of M Protease Inhibitors Encoded by SARS-CoV-2

Antimicrobial agents and chemotherapy, 2020-08, Vol.64 (9)

2020

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3D-QSAR-Assisted Drug Design: Identification of a Potent Quinazoline-Based Aurora Kinase Inhibitor

ChemMedChem, 2013-01, Vol.8 (1), p.136-148

2013

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Discovery of tetrasubstituted thiophenes as Cisd2 activators: A potential novel therapeutic option in nonalcoholic fatty liver disease

European journal of medicinal chemistry, 2023-10, Vol.258, p.115583-115583, Article 115583

2023

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Design, Synthesis, and Evaluation of Thiazolidine-2,4-dione Derivatives as a Novel Class of Glutaminase Inhibitors

Journal of medicinal chemistry, 2017-07, Vol.60 (13), p.5599-5612

2017

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Mapping the naloxone binding sites on the mu-opioid receptor using cell-based photocrosslinkers

Biochimica et biophysica acta. Proteins and proteomics, 2017-03, Vol.1865 (3), p.336-343

2017

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Development of Stem-Cell-Mobilizing Agents Targeting CXCR4 Receptor for Peripheral Blood Stem Cell Transplantation and Beyond

Journal of medicinal chemistry, 2018-02, Vol.61 (3), p.818-833

2018

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Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel opioid receptor agonists

European journal of medicinal chemistry, 2017-01, Vol.126, p.202-217

2017

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Function-Oriented Development of CXCR4 Antagonists as Selective Human Immunodeficiency Virus (HIV)‑1 Entry Inhibitors

Journal of medicinal chemistry, 2015-02, Vol.58 (3), p.1452-1465

2015

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Effects of sleeve gastrectomy plus trunk vagotomy compared with sleeve gastrectomy on glucose metabolism in diabetic rats

World journal of gastroenterology : WJG, 2017-05, Vol.23 (18), p.3269-3278

2017

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Copy number amplification of ENSA promotes the progression of triple-negative breast cancer via cholesterol biosynthesis

Nature communications, 2022-02, Vol.13 (1), p.791-791, Article 791

2022

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CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer

Nature communications, 2019-11, Vol.10 (1), p.5114-5114, Article 5114

2019

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Piceatannol Alleviates Deoxynivalenol-Induced Damage in Intestinal Epithelial Cells via Inhibition of the NF-κB Pathway

Molecules (Basel, Switzerland), 2024-02, Vol.29 (4), p.855

2024

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Hypertonic saline mediates the NLRP3/IL‐1β signaling axis in microglia to alleviate ischemic blood‐brain barrier permeability by downregulating astrocyte‐derived VEGF in rats

CNS neuroscience & therapeutics, 2020-10, Vol.26 (10), p.1045-1057

2020

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Phospholipase D Mediates Glutamine-Induced mTORC1 Activation to Promote Porcine Intestinal Epithelial Cell Proliferation

The Journal of nutrition, 2024-04, Vol.154 (4), p.1119-1129

2024

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Effects of antimicrobial peptides (AMPs) on blood biochemical parameters, antioxidase activity, and immune function in the common carp (Cyprinus carpio)

Fish & shellfish immunology, 2015-11, Vol.47 (1), p.429-434

2015

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Hypertonic saline attenuates expression of Notch signaling and proinflammatory mediators in activated microglia in experimentally induced cerebral ischemia and hypoxic BV-2 microglia

BMC neuroscience, 2017-03, Vol.18 (1), p.32-32, Article 32

2017

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Sutureless Intestinal Anastomosis with a Novel Device of Magnetic Compression Anastomosis

Chinese medical sciences journal, 2011-09, Vol.26 (3), p.182-189

2011

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14-3-3zeta is involved in the anticancer effect of metformin in colorectal carcinoma

Carcinogenesis (New York), 2018-03, Vol.39 (3), p.493-502

2018

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Huperzine A protects sepsis associated encephalopathy by promoting the deficient cholinergic nervous function

Neuroscience letters, 2016-09, Vol.631, p.70-78

2016

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Hypertonic saline alleviates cerebral edema by inhibiting microglia-derived TNF-α and IL-1β-induced Na-K-Cl Cotransporter up-regulation

Journal of neuroinflammation, 2014-06, Vol.11 (1), p.102-102, Article 102

2014

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Hepatocyte growth factor modification enhances the anti-arrhythmic properties of human bone marrow-derived mesenchymal stem cells

PloS one, 2014-10, Vol.9 (10), p.e111246-e111246

2014

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Strawberry Notch 1 (SBNO1) promotes proliferation of spermatogonial stem cells via the noncanonical Wnt pathway in mice

Asian journal of andrology, 2019-07, Vol.21 (4), p.345-350

2019

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Harnessing CXCR4 antagonists in stem cell mobilization, HIV infection, ischemic diseases, and oncology

Optimization of Ligand and Lipophilic Efficiency To Identify an in Vivo Active Furano-Pyrimidine Aurora Kinase Inhibitor

Discovery of M Protease Inhibitors Encoded by SARS-CoV-2

3D-QSAR-Assisted Drug Design: Identification of a Potent Quinazoline-Based Aurora Kinase Inhibitor

Discovery of tetrasubstituted thiophenes as Cisd2 activators: A potential novel therapeutic option in nonalcoholic fatty liver disease

Design, Synthesis, and Evaluation of Thiazolidine-2,4-dione Derivatives as a Novel Class of Glutaminase Inhibitors

Mapping the naloxone binding sites on the mu-opioid receptor using cell-based photocrosslinkers

Development of Stem-Cell-Mobilizing Agents Targeting CXCR4 Receptor for Peripheral Blood Stem Cell Transplantation and Beyond

Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel opioid receptor agonists

Function-Oriented Development of CXCR4 Antagonists as Selective Human Immunodeficiency Virus (HIV)‑1 Entry Inhibitors

Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation

Effects of sleeve gastrectomy plus trunk vagotomy compared with sleeve gastrectomy on glucose metabolism in diabetic rats

Copy number amplification of ENSA promotes the progression of triple-negative breast cancer via cholesterol biosynthesis

CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer

Piceatannol Alleviates Deoxynivalenol-Induced Damage in Intestinal Epithelial Cells via Inhibition of the NF-κB Pathway

Hypertonic saline mediates the NLRP3/IL‐1β signaling axis in microglia to alleviate ischemic blood‐brain barrier permeability by downregulating astrocyte‐derived VEGF in rats

Phospholipase D Mediates Glutamine-Induced mTORC1 Activation to Promote Porcine Intestinal Epithelial Cell Proliferation

Effects of antimicrobial peptides (AMPs) on blood biochemical parameters, antioxidase activity, and immune function in the common carp (Cyprinus carpio)

Hypertonic saline attenuates expression of Notch signaling and proinflammatory mediators in activated microglia in experimentally induced cerebral ischemia and hypoxic BV-2 microglia

Sutureless Intestinal Anastomosis with a Novel Device of Magnetic Compression Anastomosis

14-3-3zeta is involved in the anticancer effect of metformin in colorectal carcinoma

Huperzine A protects sepsis associated encephalopathy by promoting the deficient cholinergic nervous function

Hypertonic saline alleviates cerebral edema by inhibiting microglia-derived TNF-α and IL-1β-induced Na-K-Cl Cotransporter up-regulation

Hepatocyte growth factor modification enhances the anti-arrhythmic properties of human bone marrow-derived mesenchymal stem cells

Strawberry Notch 1 (SBNO1) promotes proliferation of spermatogonial stem cells via the noncanonical Wnt pathway in mice

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