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The podoplanin-CLEC-2 interaction promotes platelet-mediated melanoma pulmonary metastasis

BMC cancer, 2024-04, Vol.24 (1), p.399-399, Article 399

2024

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Core 1-derived mucin-type O-glycosylation protects against spontaneous gastritis and gastric cancer

The Journal of experimental medicine, 2020-01, Vol.217 (1)

2020

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Dclk1 in tuft cells promotes inflammation-driven epithelial restitution and mitigates chronic colitis

Cell death and differentiation, 2019-09, Vol.26 (9), p.1656-1669

2019

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The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture

Nature immunology, 2015-01, Vol.16 (1), p.75-84

2015

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Sialylation on O-glycans protects platelets from clearance by liver Kupffer cells

Proceedings of the National Academy of Sciences - PNAS, 2017-08, Vol.114 (31), p.8360-8365

2017

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Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice

Gastroenterology (New York, N.Y. 1943), 2016-07, Vol.151 (1), p.152-164.e11

2016

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Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3

Nature communications, 2016-04, Vol.7 (1), p.11302-11302, Article 11302

2016

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Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice

The Journal of clinical investigation, 2011-04, Vol.121 (4), p.1657-1666

2011

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Plasma soluble podoplanin is a novel marker for the diagnosis of tumor occurrence and metastasis

Cancer science, 2018-02, Vol.109 (2), p.403-411

2018

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O-glycans direct selectin ligands to lipid rafts on leukocytes

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (28), p.8661-8666

2015

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Loss of mucin-type O-glycans impairs the integrity of the glomerular filtration barrier in the mouse kidney

The Journal of biological chemistry, 2017-10, Vol.292 (40), p.16491-16497

2017

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Core 1-derived O-glycans are essential E-selectin ligands on neutrophils

Proceedings of the National Academy of Sciences - PNAS, 2010-05, Vol.107 (20), p.9204-9209

2010

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Discordance between changes in the gut microbiota and pathogenicity in a mouse model of spontaneous colitis

Gut microbes, 2014-05, Vol.5 (3), p.286-485

2014

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CLEC-2 and podoplanin, partners again

Blood, 2016-03, Vol.127 (13), p.1629-1630

2016

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Lymph flow regulates collecting lymphatic vessel maturation in vivo

The Journal of clinical investigation, 2015-08, Vol.125 (8), p.2995-3007

2015

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Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2

Nature (London), 2013-10, Vol.502 (7469), p.105-109

2013

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Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves

Genes & development, 2016-06, Vol.30 (12), p.1454-1469

2016

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Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life

The Journal of clinical investigation, 2014-01, Vol.124 (1), p.273-284

2014

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Disruption of C1galt1 Gene Promotes Development and Metastasis of Pancreatic Adenocarcinomas in Mice

Gastroenterology (New York, N.Y. 1943), 2018-11, Vol.155 (5), p.1608-1624

2018

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Loss of intestinal O-glycans promotes spontaneous duodenal tumors

American journal of physiology: Gastrointestinal and liver physiology, 2016-07, Vol.311 (1), p.G74-G83

2016

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Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma

Cancer research (Chicago, Ill.), 2013-12, Vol.73 (24), p.7254-7264

2013

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Podoplanin requires sialylated O-glycans for stable expression on lymphatic endothelial cells and for interaction with platelets

Blood, 2014-12, Vol.124 (24), p.3656-3665

2014

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Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice

The Journal of clinical investigation, 2008-11, Vol.118 (11), p.3725-3737

2008

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Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice

The Journal of biological chemistry, 2015-08, Vol.290 (33), p.20159-20166

2015

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Mucin-type O-glycosylation is critical for vascular integrity

Glycobiology (Oxford), 2014-12, Vol.24 (12), p.1237-1241

2014

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The podoplanin-CLEC-2 interaction promotes platelet-mediated melanoma pulmonary metastasis

Core 1-derived mucin-type O-glycosylation protects against spontaneous gastritis and gastric cancer

Dclk1 in tuft cells promotes inflammation-driven epithelial restitution and mitigates chronic colitis

The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture

Sialylation on O-glycans protects platelets from clearance by liver Kupffer cells

Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice

Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3

Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice

Plasma soluble podoplanin is a novel marker for the diagnosis of tumor occurrence and metastasis

O-glycans direct selectin ligands to lipid rafts on leukocytes

Loss of mucin-type O-glycans impairs the integrity of the glomerular filtration barrier in the mouse kidney

Core 1-derived O-glycans are essential E-selectin ligands on neutrophils

Discordance between changes in the gut microbiota and pathogenicity in a mouse model of spontaneous colitis

CLEC-2 and podoplanin, partners again

Lymph flow regulates collecting lymphatic vessel maturation in vivo

Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2

Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves

Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life

Disruption of C1galt1 Gene Promotes Development and Metastasis of Pancreatic Adenocarcinomas in Mice

Loss of intestinal O-glycans promotes spontaneous duodenal tumors

Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma

Podoplanin requires sialylated O-glycans for stable expression on lymphatic endothelial cells and for interaction with platelets

Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice

Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice

Mucin-type O-glycosylation is critical for vascular integrity

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