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‘Pro et contra’ ionic liquid drugs – Challenges and opportunities for pharmaceutical translation

European journal of pharmaceutics and biopharmaceutics, 2015-08, Vol.94, p.291-304

2015

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NMR techniques in biomedical and pharmaceutical analysis

Journal of pharmaceutical and biomedical analysis, 2011-04, Vol.55 (1), p.1-15

2011

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Quaternary Ammonium Salts and Their Antimicrobial Potential: Targets or Nonspecific Interactions?

ChemMedChem, 2012-01, Vol.7 (1), p.22-31

2012

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Bivalent and bitopic ligands of the opioid receptors: The prospects of a dual approach

Medicinal research reviews, 2024-11, Vol.44 (6), p.2545-2599

2024

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Design, synthesis and biological evaluations of quinolone amides against African trypanosomiasis with improved solubility

European journal of medicinal chemistry, 2023-03, Vol.250, p.115176-115176, Article 115176

2023

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Novel Xanomeline-Containing Bitopic Ligands of Muscarinic Acetylcholine Receptors: Design, Synthesis and FRET Investigation

Molecules (Basel, Switzerland), 2023-03, Vol.28 (5), p.2407

2023

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Do we need new drugs against human African trypanosomiasis?

The Lancet infectious diseases, 2013-09, Vol.13 (9), p.733-734

2013

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Natural Products Repertoire of the Red Sea

Marine drugs, 2020-09, Vol.18 (9), p.457

2020

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Rational design of dualsteric GPCR ligands: quests and promise

British journal of pharmacology, 2010-03, Vol.159 (5), p.997-1008

2010

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Targeting Protein Folding: A Novel Approach for the Treatment of Pathogenic Bacteria

Journal of medicinal chemistry, 2020-11, Vol.63 (22), p.13355-13388

2020

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Targeting acetylcholinesterase to treat neurodegeneration

Expert opinion on therapeutic targets, 2007-02, Vol.11 (2), p.161-179

2007

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Cinnamic Acid Bornyl Ester Derivatives from Valeriana wallichii Exhibit Antileishmanial In Vivo Activity in Leishmania major-Infected BALB/c Mice

PloS one, 2015-11, Vol.10 (11), p.e0142386

2015

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Agonists with supraphysiological efficacy at the muscarinic M2 ACh receptor

British journal of pharmacology, 2013-05, Vol.169 (2), p.357-370

2013

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Ligand Binding Ensembles Determine Graded Agonist Efficacies at a G Protein-coupled Receptor

The Journal of biological chemistry, 2016-07, Vol.291 (31), p.16375-16389

2016

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Inhibition of macrophage infectivity potentiator in Burkholderia pseudomallei suppresses pro-inflammatory responses in murine macrophages

Frontiers in cellular and infection microbiology, 2024-03, Vol.14, p.1353682-1353682

2024

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Serjanic Acid Improves Immunometabolic Markers in a Diet-Induced Obesity Mouse Model

Molecules (Basel, Switzerland), 2020-03, Vol.25 (7), p.1486

2020

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Anti-Schistosomal Activity of Cinnamic Acid Esters: Eugenyl and Thymyl Cinnamate Induce Cytoplasmic Vacuoles and Death in Schistosomula of Schistosoma mansoni

Molecules (Basel, Switzerland), 2015-06, Vol.20 (6), p.10873-10883

2015

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Rational Design of Partial Agonists for the Muscarinic M1 Acetylcholine Receptor

Journal of medicinal chemistry, 2015-01, Vol.58 (2), p.560-576

2015

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Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity

The FASEB journal, 2009-02, Vol.23 (2), p.442-450

2009

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Pharmacological, Mechanistic, and Pharmacokinetic Assessment of Novel Melatonin-Tamoxifen Drug Conjugates as Breast Cancer Drugs

Molecular pharmacology, 2019-08, Vol.96 (2), p.272-296

2019

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Mapping the pharmaceutical design space by amorphous ionic liquid strategies

Journal of controlled release, 2017-12, Vol.268, p.314-322

2017

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Acetylcholinesterase Inhibitors with Photoswitchable Inhibition of β‑Amyloid Aggregation

ACS chemical neuroscience, 2014-05, Vol.5 (5), p.377-389

2014

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Bistacrine derivatives as new potent antimalarials

Bioorganic & medicinal chemistry, 2016-08, Vol.24 (16), p.3636-3642

2016

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Allosteric ligands for G protein-coupled receptors: A novel strategy with attractive therapeutic opportunities

Medicinal research reviews, 2010-05, Vol.30 (3), p.463-549

2010

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Comparison of pharmacological activities of three distinct kappa ligands (Salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo

The Journal of pharmacology and experimental therapeutics, 2005-01, Vol.312 (1), p.220-230

2005

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‘Pro et contra’ ionic liquid drugs – Challenges and opportunities for pharmaceutical translation

NMR techniques in biomedical and pharmaceutical analysis

Quaternary Ammonium Salts and Their Antimicrobial Potential: Targets or Nonspecific Interactions?

Bivalent and bitopic ligands of the opioid receptors: The prospects of a dual approach

Design, synthesis and biological evaluations of quinolone amides against African trypanosomiasis with improved solubility

Novel Xanomeline-Containing Bitopic Ligands of Muscarinic Acetylcholine Receptors: Design, Synthesis and FRET Investigation

Do we need new drugs against human African trypanosomiasis?

Natural Products Repertoire of the Red Sea

Rational design of dualsteric GPCR ligands: quests and promise

Targeting Protein Folding: A Novel Approach for the Treatment of Pathogenic Bacteria

Targeting acetylcholinesterase to treat neurodegeneration

Cinnamic Acid Bornyl Ester Derivatives from Valeriana wallichii Exhibit Antileishmanial In Vivo Activity in Leishmania major-Infected BALB/c Mice

Agonists with supraphysiological efficacy at the muscarinic M2 ACh receptor

Ligand Binding Ensembles Determine Graded Agonist Efficacies at a G Protein-coupled Receptor

Inhibition of macrophage infectivity potentiator in Burkholderia pseudomallei suppresses pro-inflammatory responses in murine macrophages

Serjanic Acid Improves Immunometabolic Markers in a Diet-Induced Obesity Mouse Model

Anti-Schistosomal Activity of Cinnamic Acid Esters: Eugenyl and Thymyl Cinnamate Induce Cytoplasmic Vacuoles and Death in Schistosomula of Schistosoma mansoni

Rational Design of Partial Agonists for the Muscarinic M1 Acetylcholine Receptor

Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity

Pharmacological, Mechanistic, and Pharmacokinetic Assessment of Novel Melatonin-Tamoxifen Drug Conjugates as Breast Cancer Drugs

Mapping the pharmaceutical design space by amorphous ionic liquid strategies

Acetylcholinesterase Inhibitors with Photoswitchable Inhibition of β‑Amyloid Aggregation

Bistacrine derivatives as new potent antimalarials

Allosteric ligands for G protein-coupled receptors: A novel strategy with attractive therapeutic opportunities

Comparison of pharmacological activities of three distinct kappa ligands (Salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo

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