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Crystal structure of the ligand-free G-protein-coupled receptor opsin

Nature, 2008-07, Vol.454 (7201), p.183-187

2008

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Precision vs Flexibility in GPCR signaling

Journal of the American Chemical Society, 2013-08, Vol.135 (33), p.12305-12312

2013

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Crystal structure of opsin in its G-protein-interacting conformation

Nature, 2008-09, Vol.455 (7212), p.497-502

2008

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High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation

Proceedings of the National Academy of Sciences - PNAS, 2008-05, Vol.105 (21), p.7439-7444

2008

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Crystal structure of a common GPCR-binding interface for G protein and arrestin

Nature communications, 2014-09, Vol.5 (1), p.4801-4801, Article 4801

2014

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Position of Transmembrane Helix 6 Determines Receptor G Protein Coupling Specificity

Journal of the American Chemical Society, 2014-08, Vol.136 (32), p.11244-11247

2014

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Sequence of Late Molecular Events in the Activation of Rhodopsin

Proceedings of the National Academy of Sciences - PNAS, 2007-12, Vol.104 (51), p.20290-20295

2007

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Hydrocortisone preserves the vascular barrier by protecting the endothelial glycocalyx

Anesthesiology (Philadelphia), 2007-11, Vol.107 (5), p.776-784

2007

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Rhodopsin, light-sensor of vision

Progress in retinal and eye research, 2023-03, Vol.93, p.101116-101116, Article 101116

2023

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Activation of rhodopsin: new insights from structural and biochemical studies

Trends in Biochemical Sciences, 2001-05, Vol.26 (5), p.318-324

2001

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Role of the Conserved NPxxY(x)5,6F Motif in the Rhodopsin Ground State and during Activation

Proceedings of the National Academy of Sciences - PNAS, 2003-03, Vol.100 (5), p.2290-2295

2003

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It takes two transducins to activate the cGMP-phosphodiesterase 6 in retinal rods

Open biology, 2018-08, Vol.8 (8)

2018

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Spatial and Temporal Aspects of Signaling by G-Protein-Coupled Receptors

Molecular pharmacology, 2015-09, Vol.88 (3), p.572-578

2015

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Micropatterned immobilization of a G protein-coupled receptor and direct detection of G protein activation

Nature biotechnology, 1999-11, Vol.17 (11), p.1105-1108

1999

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Retinol Dehydrogenase (RDH12) Protects Photoreceptors from Light-induced Degeneration in Mice

The Journal of biological chemistry, 2006-12, Vol.281 (49), p.37697-37704

2006

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Calcium-Dependent Assembly of Centrin-G-Protein Complex in Photoreceptor Cells

Molecular and Cellular Biology, 2002-04, Vol.22 (7), p.2194-2203

2002

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Crystal structure of pre-activated arrestin p44

Nature (London), 2013-05, Vol.497 (7447), p.142-146

2013

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A G protein-coupled receptor at work: the rhodopsin model

Trends in biochemical sciences (Amsterdam. Regular ed.), 2009-11, Vol.34 (11), p.540-552

2009

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Sequence of Interactions in Receptor-G Protein Coupling

The Journal of biological chemistry, 2004-06, Vol.279 (23), p.24283-24290

2004

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Differential Expression and Interaction with the Visual G-protein Transducin of Centrin Isoforms in Mammalian Photoreceptor Cells

The Journal of biological chemistry, 2004-12, Vol.279 (49), p.51472-51481

2004

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Distinct loops in arrestin differentially regulate ligand binding within the GPCR opsin

Nature communications, 2012, Vol.3 (1), p.995, Article 995

2012

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Transition of Rhodopsin into the Active Metarhodopsin II State Opens a New Light-induced Pathway Linked to Schiff Base Isomerization

The Journal of biological chemistry, 2004-11, Vol.279 (46), p.48102-48111

2004

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Signal Transfer from Rhodopsin to the G-Protein: Evidence for a Two-Site Sequential Fit Mechanism

Proceedings of the National Academy of Sciences - PNAS, 1999-04, Vol.96 (9), p.4898-4903

1999

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Rhodopsin Mutants that Bind but Fail to Activate Transducin

Science (American Association for the Advancement of Science), 1990-10, Vol.250 (4977), p.123-125

1990

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Diffusible Ligand All-trans-retinal Activates Opsin via a Palmitoylation-dependent Mechanism

The Journal of biological chemistry, 2000-03, Vol.275 (9), p.6189-6194

2000

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Crystal structure of the ligand-free G-protein-coupled receptor opsin

Precision vs Flexibility in GPCR signaling

Crystal structure of opsin in its G-protein-interacting conformation

High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation

Crystal structure of a common GPCR-binding interface for G protein and arrestin

Position of Transmembrane Helix 6 Determines Receptor G Protein Coupling Specificity

Sequence of Late Molecular Events in the Activation of Rhodopsin

Hydrocortisone preserves the vascular barrier by protecting the endothelial glycocalyx

Rhodopsin, light-sensor of vision

Activation of rhodopsin: new insights from structural and biochemical studies

Role of the Conserved NPxxY(x)5,6F Motif in the Rhodopsin Ground State and during Activation

It takes two transducins to activate the cGMP-phosphodiesterase 6 in retinal rods

Spatial and Temporal Aspects of Signaling by G-Protein-Coupled Receptors

Micropatterned immobilization of a G protein-coupled receptor and direct detection of G protein activation

Retinol Dehydrogenase (RDH12) Protects Photoreceptors from Light-induced Degeneration in Mice

Calcium-Dependent Assembly of Centrin-G-Protein Complex in Photoreceptor Cells

Crystal structure of pre-activated arrestin p44

A G protein-coupled receptor at work: the rhodopsin model

Sequence of Interactions in Receptor-G Protein Coupling

Differential Expression and Interaction with the Visual G-protein Transducin of Centrin Isoforms in Mammalian Photoreceptor Cells

Distinct loops in arrestin differentially regulate ligand binding within the GPCR opsin

Transition of Rhodopsin into the Active Metarhodopsin II State Opens a New Light-induced Pathway Linked to Schiff Base Isomerization

Signal Transfer from Rhodopsin to the G-Protein: Evidence for a Two-Site Sequential Fit Mechanism

Rhodopsin Mutants that Bind but Fail to Activate Transducin

Diffusible Ligand All-trans-retinal Activates Opsin via a Palmitoylation-dependent Mechanism

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