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Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies

Blood, 2018-01, Vol.131 (3), p.328-341

2018

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The genetics of uveal melanoma: an emerging framework for targeted therapy

Pigment cell and melanoma research, 2012-03, Vol.25 (2), p.171-181

Harbour, J. William

2012

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BAP1 deficiency causes loss of melanocytic cell identity in uveal melanoma

BMC cancer, 2013-08, Vol.13 (1), p.371-371, Article 371

2013

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Primary Vitreoretinal Lymphoma: A Report from an International Primary Central Nervous System Lymphoma Collaborative Group Symposium

The oncologist (Dayton, Ohio), 2011-11, Vol.16 (11), p.1589-1599

2011

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Impaired Cholesterol Efflux in Senescent Macrophages Promotes Age-Related Macular Degeneration

Cell metabolism, 2013-04, Vol.17 (4), p.549-561

2013

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GNAQ/11 Mutations in Uveal Melanoma: Is YAP the Key to Targeted Therapy?

Cancer cell, 2014-06, Vol.25 (6), p.714-715

2014

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ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma

Cancer cell, 2016-06, Vol.29 (6), p.889-904

2016

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Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma

Clinical cancer research, 2012-01, Vol.18 (2), p.408-416

2012

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MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A

The Journal of cell biology, 2005-01, Vol.168 (1), p.35-40

2005

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Combined PKC and MEK inhibition for treating metastatic uveal melanoma

Oncogene, 2014-09, Vol.33 (39), p.4722-4723

2014

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BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers

Science advances, 2019-09, Vol.5 (9), p.eaax1738-eaax1738

2019

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Reduced BAP1 activity prevents ASXL1 truncation-driven myeloid malignancy in vivo

Leukemia, 2018-08, Vol.32 (8), p.1834-1837

2018

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Activation of NFAT by HGF and IGF-1 via ARF6 and its effector ASAP1 promotes uveal melanoma metastasis

Oncogene, 2023-08, Vol.42 (35), p.2629-2640

2023

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BAP1 is required prenatally for differentiation and maintenance of postnatal murine enteric nervous system

The Journal of clinical investigation, 2024-05, Vol.134 (9), p.1-17

2024

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Notch Signaling Promotes Growth and Invasion in Uveal Melanoma

Clinical cancer research, 2012-02, Vol.18 (3), p.654-665

2012

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Functional gene expression analysis uncovers phenotypic switch in aggressive uveal melanomas

Cancer research (Chicago, Ill.), 2006-05, Vol.66 (9), p.4602-4609

2006

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Decitabine limits escape from MEK inhibition in uveal melanoma

Pigment cell and melanoma research, 2020-05, Vol.33 (3), p.507-514

2020

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Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase

Molecular cancer research, 2021-07, Vol.19 (7), p.1099-1112

2021

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Rb at the interface between cell cycle and apoptotic decisions

Current molecular medicine, 2006-11, Vol.6 (7), p.713-718

2006

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Emerging insights into the molecular pathogenesis of uveal melanoma

Future oncology (London, England), 2008-10, Vol.4 (5), p.629-636

2008

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ABCB1 identifies a subpopulation of uveal melanoma cells with high metastatic propensity

Pigment cell and melanoma research, 2011-06, Vol.24 (3), p.430-437

2011

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ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis

Science advances, 2017-01, Vol.3 (1), p.e1601602-e1601602

2017

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Chromatin remodeling and Rb activity

Current Opinion in Cell Biology, 2000-12, Vol.12 (6), p.685-689

2000

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Preclinical Acute Ocular Safety Study of Combined Intravitreal Carboplatin and Etoposide Phosphate for Retinoblastoma

Ophthalmic surgery, lasers & imaging retina, 2017-02, Vol.48 (2), p.151-159

2017

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Distinct Mechanisms for Regulating the Tumor Suppressor and Antiapoptotic Functions of Rb

The Journal of biological chemistry, 2003-05, Vol.278 (21), p.19358-19366

2003

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Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies

The genetics of uveal melanoma: an emerging framework for targeted therapy

BAP1 deficiency causes loss of melanocytic cell identity in uveal melanoma

Primary Vitreoretinal Lymphoma: A Report from an International Primary Central Nervous System Lymphoma Collaborative Group Symposium

Impaired Cholesterol Efflux in Senescent Macrophages Promotes Age-Related Macular Degeneration

GNAQ/11 Mutations in Uveal Melanoma: Is YAP the Key to Targeted Therapy?

ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma

Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma

MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A

Combined PKC and MEK inhibition for treating metastatic uveal melanoma

BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers

Reduced BAP1 activity prevents ASXL1 truncation-driven myeloid malignancy in vivo

Activation of NFAT by HGF and IGF-1 via ARF6 and its effector ASAP1 promotes uveal melanoma metastasis

BAP1 is required prenatally for differentiation and maintenance of postnatal murine enteric nervous system

Notch Signaling Promotes Growth and Invasion in Uveal Melanoma

Functional gene expression analysis uncovers phenotypic switch in aggressive uveal melanomas

Decitabine limits escape from MEK inhibition in uveal melanoma

Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase

Rb at the interface between cell cycle and apoptotic decisions

Emerging insights into the molecular pathogenesis of uveal melanoma

ABCB1 identifies a subpopulation of uveal melanoma cells with high metastatic propensity

ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis

Chromatin remodeling and Rb activity

Preclinical Acute Ocular Safety Study of Combined Intravitreal Carboplatin and Etoposide Phosphate for Retinoblastoma

Distinct Mechanisms for Regulating the Tumor Suppressor and Antiapoptotic Functions of Rb

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