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Control of misincorporation of serine for asparagine during antibody production using CHO cells

Biotechnology and bioengineering, 2010-09, Vol.107 (1), p.116-123

2010

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Discovery and Investigation of Misincorporation of Serine at Asparagine Positions in Recombinant Proteins Expressed in Chinese Hamster Ovary Cells

The Journal of biological chemistry, 2009-11, Vol.284 (47), p.32686-32694

2009

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Selectivity of BAFF/BLyS and APRIL for Binding to the TNF Family Receptors BAFFR/BR3 and BCMA

Biochemistry (Easton), 2005-02, Vol.44 (6), p.1919-1931

2005

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Identification of a Palmitic Acid-modified Form of Human Sonic hedgehog

The Journal of biological chemistry, 1998-05, Vol.273 (22), p.14037-14045

1998

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Growth Factor Induction of Cripto-1 Shedding by Glycosylphosphatidylinositol-Phospholipase D and Enhancement of Endothelial Cell Migration

The Journal of biological chemistry, 2007-10, Vol.282 (43), p.31643-31655

2007

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Production of a PEGylated Fab′ of the anti-LINGO-1 Li33 Antibody and Assessment of Its Biochemical and Functional Properties in Vitro and in a Rat Model of Remyelination

Bioconjugate chemistry, 2011-02, Vol.22 (2), p.200-210

2011

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Resolution of disulfide heterogeneity in Nogo receptor I fusion proteins by molecular engineering

Biotechnology and applied biochemistry, 2010-09, Vol.57 (1), p.31-45

2010

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Long‐acting forms of Sonic hedgehog with improved pharmacokinetic and pharmacodynamic properties are efficacious in a nerve injury model

Journal of pharmaceutical sciences, 2002-02, Vol.91 (2), p.371-387

2002

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A Prodomain Fragment from the Proteolytic Activation of Growth Differentiation Factor 11 Remains Associated with the Mature Growth Factor and Keeps It Soluble

Biochemistry (Easton), 2017-08, Vol.56 (33), p.4405-4418

2017

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Characterization of trisulfide modification in antibodies

Analytical biochemistry, 2010-05, Vol.400 (1), p.89-98

2010

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Determination of the Disulfide Structure of Murine Meteorin, a Neurotrophic Factor, by LC–MS and Electron Transfer Dissociation-High-Energy Collisional Dissociation Analysis of Proteolytic Fragments

Analytical chemistry (Washington), 2017-04, Vol.89 (7), p.4021-4030

2017

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Discovery and Investigation of O‑Xylosylation in Engineered Proteins Containing a (GGGGS) n Linker

Analytical chemistry (Washington), 2013-05, Vol.85 (9), p.4805-4812

2013

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Expression of Sonic hedgehog-Fc fusion protein in Pichia pastoris. Identification and control of post-translational, chemical, and proteolytic modifications

Protein expression and purification, 2003-06, Vol.29 (2), p.272-283

2003

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Picomole-level mapping of protein disulfides by mass spectrometry following partial reduction and alkylation

Analytical biochemistry, 2008-06, Vol.377 (1), p.95-104

2008

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N-terminally PEGylated human interferon-beta-1a with improved pharmacokinetic properties and in vivo efficacy in a melanoma angiogenesis model

Bioconjugate chemistry, 2006-01, Vol.17 (1), p.179-188

2006

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Engineering potent long-acting variants of the Wnt inhibitor DKK2

Protein engineering, design and selection, 2017-05, Vol.30 (5), p.359-372

2017

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Structure-function relationships in an antifreeze polypeptide. The role of neutral, polar amino acids

The Journal of biological chemistry, 1992-07, Vol.267 (20), p.14102-14108

1992

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An antibody–cytotoxic conjugate, BIIB015, is a new targeted therapy for Cripto positive tumours

European journal of cancer (1990), 2011-07, Vol.47 (11), p.1736-1746

2011

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A d-antifreeze polypeptide displays the same activity as its natural l-enantiomer

FEBS letters, 1993-02, Vol.317 (1), p.31-34

1993

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Enhanced Potency of Human Sonic Hedgehog by Hydrophobic Modification

Biochemistry (Easton), 2001-04, Vol.40 (14), p.4359-4371

2001

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Nonequilibrium Antifreeze Peptides and the Recrystallization of Ice

Cryobiology, 1995-02, Vol.32 (1), p.23-34

1995

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A model for binding of an antifreeze polypeptide to ice

Biophysical journal, 1992-12, Vol.63 (6), p.1659-1662

1992

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Expression, purification, and characterization of rat interferon-β, and preparation of an N-terminally PEGylated form with improved pharmacokinetic parameters

Protein expression and purification, 2004-04, Vol.34 (2), p.229-242

2004

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The Plasma and Cytoplasmic Forms of Human Gelsolin Differ in Disulfide Structure

Biochemistry (Easton), 1996-07, Vol.35 (30), p.9700-9709

1996

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Zinc-Dependent Structural Stability of Human Sonic Hedgehog

Biochemistry (Easton), 1999-11, Vol.38 (45), p.14868-14880

1999

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Control of misincorporation of serine for asparagine during antibody production using CHO cells

Discovery and Investigation of Misincorporation of Serine at Asparagine Positions in Recombinant Proteins Expressed in Chinese Hamster Ovary Cells

Selectivity of BAFF/BLyS and APRIL for Binding to the TNF Family Receptors BAFFR/BR3 and BCMA

Identification of a Palmitic Acid-modified Form of Human Sonic hedgehog

Growth Factor Induction of Cripto-1 Shedding by Glycosylphosphatidylinositol-Phospholipase D and Enhancement of Endothelial Cell Migration

Production of a PEGylated Fab′ of the anti-LINGO-1 Li33 Antibody and Assessment of Its Biochemical and Functional Properties in Vitro and in a Rat Model of Remyelination

Resolution of disulfide heterogeneity in Nogo receptor I fusion proteins by molecular engineering

Long‐acting forms of Sonic hedgehog with improved pharmacokinetic and pharmacodynamic properties are efficacious in a nerve injury model

A Prodomain Fragment from the Proteolytic Activation of Growth Differentiation Factor 11 Remains Associated with the Mature Growth Factor and Keeps It Soluble

Characterization of trisulfide modification in antibodies

Determination of the Disulfide Structure of Murine Meteorin, a Neurotrophic Factor, by LC–MS and Electron Transfer Dissociation-High-Energy Collisional Dissociation Analysis of Proteolytic Fragments

Discovery and Investigation of O‑Xylosylation in Engineered Proteins Containing a (GGGGS) n Linker

Expression of Sonic hedgehog-Fc fusion protein in Pichia pastoris. Identification and control of post-translational, chemical, and proteolytic modifications

Picomole-level mapping of protein disulfides by mass spectrometry following partial reduction and alkylation

N-terminally PEGylated human interferon-beta-1a with improved pharmacokinetic properties and in vivo efficacy in a melanoma angiogenesis model

Engineering potent long-acting variants of the Wnt inhibitor DKK2

Structure-function relationships in an antifreeze polypeptide. The role of neutral, polar amino acids

An antibody–cytotoxic conjugate, BIIB015, is a new targeted therapy for Cripto positive tumours

A d-antifreeze polypeptide displays the same activity as its natural l-enantiomer

Enhanced Potency of Human Sonic Hedgehog by Hydrophobic Modification

Nonequilibrium Antifreeze Peptides and the Recrystallization of Ice

A model for binding of an antifreeze polypeptide to ice

Expression, purification, and characterization of rat interferon-β, and preparation of an N-terminally PEGylated form with improved pharmacokinetic parameters

The Plasma and Cytoplasmic Forms of Human Gelsolin Differ in Disulfide Structure

Zinc-Dependent Structural Stability of Human Sonic Hedgehog

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