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Genetically modified, live attenuated dengue virus type 3 vaccine candidates

The American journal of tropical medicine and hygiene, 2004-12, Vol.71 (6), p.811-821

2004

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Recombinant, Live-Attenuated Tetravalent Dengue Virus Vaccine Formulations Induce a Balanced, Broad, and Protective Neutralizing Antibody Response against Each of the Four Serotypes in Rhesus Monkeys

Journal of Virology, 2005-05, Vol.79 (9), p.5516-5528

2005

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Monkeypox virus infection of rhesus macaques induces massive expansion of natural killer cells but suppresses natural killer cell functions

PloS one, 2013-10, Vol.8 (10), p.e77804

2013

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Prospects for a dengue virus vaccine

Nature reviews. Microbiology, 2007-07, Vol.5 (7), p.518-528

2007

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A Live, Attenuated Dengue Virus Type 1 Vaccine Candidate with a 30-Nucleotide Deletion in the 3′ Untranslated Region Is Highly Attenuated and Immunogenic in Monkeys

Journal of Virology, 2003-01, Vol.77 (2), p.1653-1657

2003

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Inactivated or Live-Attenuated Bivalent Vaccines That Confer Protection against Rabies and Ebola Viruses

Journal of Virology, 2011-10, Vol.85 (20), p.10605-10616

2011

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Comparative Analysis of Monkeypox Virus Infection of Cynomolgus Macaques by the Intravenous or Intrabronchial Inoculation Route

Journal of Virology, 2011-03, Vol.85 (5), p.2112-2125

2011

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Vaccine candidates derived from a novel infectious cDNA clone of an American genotype dengue virus type 2

BMC infectious diseases, 2004-10, Vol.4 (1), p.39-39, Article 39

2004

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Discovery of Potent and Selective Pyrazolopyrimidine Janus Kinase 2 Inhibitors

Journal of medicinal chemistry, 2012-11, Vol.55 (22), p.10090-10107

2012

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Substitution of the structural genes of dengue virus type 4 with those of type 2 results in chimeric vaccine candidates which are attenuated for mosquitoes, mice, and rhesus monkeys

Vaccine, 2003-10, Vol.21 (27), p.4307-4316

2003

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Dengue virus type 3 vaccine candidates generated by introduction of deletions in the 3′ untranslated region (3′-UTR) or by exchange of the DENV-3 3′-UTR with that of DENV-4

Vaccine, 2008-02, Vol.26 (6), p.817-828

2008

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Paired Charge-to-Alanine Mutagenesis of Dengue Virus Type 4 NS5 Generates Mutants with Temperature-Sensitive, Host Range, and Mouse Attenuation Phenotypes

Journal of Virology, 2002-01, Vol.76 (2), p.525-531

2002

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Antiviral activity of the EB peptide against zoonotic poxviruses

Virology journal, 2012-01, Vol.9 (1), p.6-6, Article 6

2012

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[ 18 F]-Fluorodeoxyglucose Uptake in Lymphoid Tissue Serves as a Predictor of Disease Outcome in the Nonhuman Primate Model of Monkeypox Virus Infection

Journal of virology, 2017-11, Vol.91 (21)

2017

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Mutations which enhance the replication of dengue virus type 4 and an antigenic chimeric dengue virus type 2/4 vaccine candidate in Vero cells

Vaccine, 2003-10, Vol.21 (27), p.4317-4327

2003

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Genetic Basis of Attenuation of Dengue Virus Type 4 Small Plaque Mutants with Restricted Replication in Suckling Mice and in SCID Mice Transplanted with Human Liver Cells

Virology (New York, N.Y.), 2002-08, Vol.300 (1), p.125-139

2002

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Discovery of a First-In-Class Small Molecule Antagonist against the Adrenomedullin‑2 Receptor: Structure–Activity Relationships and Optimization

Journal of medicinal chemistry, 2021-03, Vol.64 (6), p.3299-3319

2021

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A trade-off in replication in mosquito versus mammalian systems conferred by a point mutation in the NS4B protein of dengue virus type 4

Virology (New York, N.Y.), 2003-07, Vol.312 (1), p.222-232

2003

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Chemical Mutagenesis of Dengue Virus Type 4 Yields Mutant Viruses Which Are Temperature Sensitive in Vero Cells or Human Liver Cells and Attenuated in Mice

Journal of Virology, 2001-10, Vol.75 (20), p.9731-9740

2001

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Evaluation of Monkeypox Disease Progression by Molecular Imaging

The Journal of infectious diseases, 2011-12, Vol.204 (12), p.1902-1911

2011

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Exposure of rhesus monkeys to cowpox virus Brighton Red by large-particle aerosol droplets results in an upper respiratory tract disease

Journal of general virology, 2016-08, Vol.97 (8), p.1942-1954

2016

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Simian hemorrhagic fever virus infection of rhesus macaques as a model of viral hemorrhagic fever: Clinical characterization and risk factors for severe disease

Virology (New York, N.Y.), 2011-12, Vol.421 (2), p.129-140

2011

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Immunization with a Single Major Histocompatibility Complex Class I-Restricted Cytotoxic T-Lymphocyte Recognition Epitope of Herpes Simplex Virus Type 2 Confers Protective Immunity

Journal of Virology, 1998-12, Vol.72 (12), p.9567-9574

1998

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Introduction of mutations into the non-structural genes or 3′ untranslated region of an attenuated dengue virus type 4 vaccine candidate further decreases replication in rhesus monkeys while retaining protective immunity

Vaccine, 2004-09, Vol.22 (25), p.3440-3448

2004

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Evaluation of St. Louis encephalitis virus/dengue virus type 4 antigenic chimeric viruses in mice and rhesus monkeys

Vaccine, 2008-08, Vol.26 (33), p.4150-4159

2008

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Genetically modified, live attenuated dengue virus type 3 vaccine candidates

Recombinant, Live-Attenuated Tetravalent Dengue Virus Vaccine Formulations Induce a Balanced, Broad, and Protective Neutralizing Antibody Response against Each of the Four Serotypes in Rhesus Monkeys

Monkeypox virus infection of rhesus macaques induces massive expansion of natural killer cells but suppresses natural killer cell functions

Prospects for a dengue virus vaccine

A Live, Attenuated Dengue Virus Type 1 Vaccine Candidate with a 30-Nucleotide Deletion in the 3′ Untranslated Region Is Highly Attenuated and Immunogenic in Monkeys

Inactivated or Live-Attenuated Bivalent Vaccines That Confer Protection against Rabies and Ebola Viruses

Comparative Analysis of Monkeypox Virus Infection of Cynomolgus Macaques by the Intravenous or Intrabronchial Inoculation Route

Vaccine candidates derived from a novel infectious cDNA clone of an American genotype dengue virus type 2

Discovery of Potent and Selective Pyrazolopyrimidine Janus Kinase 2 Inhibitors

Substitution of the structural genes of dengue virus type 4 with those of type 2 results in chimeric vaccine candidates which are attenuated for mosquitoes, mice, and rhesus monkeys

Dengue virus type 3 vaccine candidates generated by introduction of deletions in the 3′ untranslated region (3′-UTR) or by exchange of the DENV-3 3′-UTR with that of DENV-4

Paired Charge-to-Alanine Mutagenesis of Dengue Virus Type 4 NS5 Generates Mutants with Temperature-Sensitive, Host Range, and Mouse Attenuation Phenotypes

Antiviral activity of the EB peptide against zoonotic poxviruses

[ 18 F]-Fluorodeoxyglucose Uptake in Lymphoid Tissue Serves as a Predictor of Disease Outcome in the Nonhuman Primate Model of Monkeypox Virus Infection

Mutations which enhance the replication of dengue virus type 4 and an antigenic chimeric dengue virus type 2/4 vaccine candidate in Vero cells

Genetic Basis of Attenuation of Dengue Virus Type 4 Small Plaque Mutants with Restricted Replication in Suckling Mice and in SCID Mice Transplanted with Human Liver Cells

Discovery of a First-In-Class Small Molecule Antagonist against the Adrenomedullin‑2 Receptor: Structure–Activity Relationships and Optimization

A trade-off in replication in mosquito versus mammalian systems conferred by a point mutation in the NS4B protein of dengue virus type 4

Chemical Mutagenesis of Dengue Virus Type 4 Yields Mutant Viruses Which Are Temperature Sensitive in Vero Cells or Human Liver Cells and Attenuated in Mice

Evaluation of Monkeypox Disease Progression by Molecular Imaging

Exposure of rhesus monkeys to cowpox virus Brighton Red by large-particle aerosol droplets results in an upper respiratory tract disease

Simian hemorrhagic fever virus infection of rhesus macaques as a model of viral hemorrhagic fever: Clinical characterization and risk factors for severe disease

Immunization with a Single Major Histocompatibility Complex Class I-Restricted Cytotoxic T-Lymphocyte Recognition Epitope of Herpes Simplex Virus Type 2 Confers Protective Immunity

Introduction of mutations into the non-structural genes or 3′ untranslated region of an attenuated dengue virus type 4 vaccine candidate further decreases replication in rhesus monkeys while retaining protective immunity

Evaluation of St. Louis encephalitis virus/dengue virus type 4 antigenic chimeric viruses in mice and rhesus monkeys

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