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BiTEs: bispecific antibody constructs with unique anti-tumor activity

Drug discovery today, 2005-09, Vol.10 (18), p.1237-1244

2005

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Nuclear factor kappa B, a mediator of lipopolysaccharide effects

Immunobiology (1979), 1993-04, Vol.187 (3-5), p.233-256

1993

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NF-κB: Ten Years After

Cell, 1996-10, Vol.87 (1), p.13-20

1996

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Function and activation of NF-κB in the immune system

Annual review of immunology, 1994, Vol.12, p.141-179

1994

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MT110: A novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors

Molecular Immunology, 2006-03, Vol.43 (8), p.1129-1143

2006

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Extremely potent, rapid and costimulation‐independent cytotoxic T‐cell response against lymphoma cells catalyzed by a single‐chain bispecific antibody

International journal of cancer, 2002-08, Vol.100 (6), p.690-697

2002

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Cellular and complement-dependent cytotoxicity of Ep-CAM-specific monoclonal antibody MT201 against breast cancer cell lines

British journal of cancer, 2005-01, Vol.92 (2), p.342-349

2005

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T Cell Costimulus-Independent and Very Efficacious Inhibition of Tumor Growth in Mice Bearing Subcutaneous or Leukemic Human B Cell Lymphoma Xenografts by a CD19-/CD3- Bispecific Single-Chain Antibody Construct

The Journal of immunology (1950), 2003-04, Vol.170 (8), p.4397-4402

2003

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NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules

Advances in immunology, 1997, Vol.65, p.111-137

1997

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Eradication of tumors from a human colon cancer cell line and from ovarian cancer metastases in immunodeficient mice by a single-chain Ep-CAM-/CD3-bispecific antibody construct

Cancer research (Chicago, Ill.), 2005-04, Vol.65 (7), p.2882-2889

2005

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A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF‐kappa B

The EMBO journal, 1995-06, Vol.14 (11), p.2580-2588

1995

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The ER-overload response: activation of NF-κB

Trends in Biochemical Sciences, 1997-02, Vol.22 (2), p.63-67

1997

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Role of nuclear factor-kappa B in atherogenesis

Experimental physiology, 1997-03, Vol.82 (2), p.297-304

1997

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T-cell activation and B-cell depletion in chimpanzees treated with a bispecific anti-CD19/anti-CD3 single-chain antibody construct

Cancer Immunology, Immunotherapy, 2006-05, Vol.55 (5), p.503-514

2006

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Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion

The Journal of clinical investigation, 1996-04, Vol.97 (7), p.1715-1722

1996

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Molecular Mechanisms in Down-Regulation of Tumor Necrosis Factor Expression

Proceedings of the National Academy of Sciences - PNAS, 1990-12, Vol.87 (24), p.9563-9567

1990

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Selective Activation of NF-κB by Nerve Growth Factor Through the Neurotrophin Receptor p75

Science (American Association for the Advancement of Science), 1996-04, Vol.272 (5261), p.542-545

1996

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The inducible transcription activator NF-κB: regulation by distinct protein subunits

Biochimica et biophysica acta, 1991-04, Vol.1072 (1), p.63-80

Baeuerle, Patrick A.

1991

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Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis

Nature (London), 1995-05, Vol.375 (6526), p.81-83

1995

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The p65 subunit is responsible for the strong transcription activating potential of NF‐kappa B

The EMBO journal, 1991-12, Vol.10 (12), p.3805-3817

1991

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The inducible transcription factor NF-κB : structure-function relationship of its protein subunits

Biochemical journal, 1993-03, Vol.290 (2), p.297-308

1993

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Stimulation of Ionotropic Glutamate Receptors Activates Transcription Factor NF-κB in Primary Neurons

Proceedings of the National Academy of Sciences - PNAS, 1995-10, Vol.92 (21), p.9618-9622

1995

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Constitutive NF-kappa B activity in neurons

Molecular and Cellular Biology, 1994-06, Vol.14 (6), p.3981-3992

1994

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Redox signalling by transcription factors NF-κB and AP-1 in lymphocytes

Biochemical pharmacology, 1995-09, Vol.50 (6), p.735-741

1995

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In vitro and in vivo activity of MT201, a fully human monoclonal antibody for pancarcinoma treatment

International journal of cancer, 2002-07, Vol.100 (1), p.101-110

2002

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BiTEs: bispecific antibody constructs with unique anti-tumor activity

Nuclear factor kappa B, a mediator of lipopolysaccharide effects

NF-κB: Ten Years After

Function and activation of NF-κB in the immune system

MT110: A novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors

Extremely potent, rapid and costimulation‐independent cytotoxic T‐cell response against lymphoma cells catalyzed by a single‐chain bispecific antibody

Cellular and complement-dependent cytotoxicity of Ep-CAM-specific monoclonal antibody MT201 against breast cancer cell lines

T Cell Costimulus-Independent and Very Efficacious Inhibition of Tumor Growth in Mice Bearing Subcutaneous or Leukemic Human B Cell Lymphoma Xenografts by a CD19-/CD3- Bispecific Single-Chain Antibody Construct

NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules

Eradication of tumors from a human colon cancer cell line and from ovarian cancer metastases in immunodeficient mice by a single-chain Ep-CAM-/CD3-bispecific antibody construct

A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF‐kappa B

The ER-overload response: activation of NF-κB

Role of nuclear factor-kappa B in atherogenesis

T-cell activation and B-cell depletion in chimpanzees treated with a bispecific anti-CD19/anti-CD3 single-chain antibody construct

Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion

Molecular Mechanisms in Down-Regulation of Tumor Necrosis Factor Expression

Selective Activation of NF-κB by Nerve Growth Factor Through the Neurotrophin Receptor p75

The inducible transcription activator NF-κB: regulation by distinct protein subunits

Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis

The p65 subunit is responsible for the strong transcription activating potential of NF‐kappa B

The inducible transcription factor NF-κB : structure-function relationship of its protein subunits

Stimulation of Ionotropic Glutamate Receptors Activates Transcription Factor NF-κB in Primary Neurons

Constitutive NF-kappa B activity in neurons

Redox signalling by transcription factors NF-κB and AP-1 in lymphocytes

In vitro and in vivo activity of MT201, a fully human monoclonal antibody for pancarcinoma treatment

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